48 Publications (Page 1 of 2)
2024
Coordinated in confined migration: crosstalk between the nucleus and ion channel-mediated mechanosensation. Trends in Cell Biology
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Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion
The impact of tumor microenvironment: unraveling the role of physical cues in breast cancer progression. Cancer metastasis reviews
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2023
Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement.Law, Robert A⋅Kiepas, Alexander⋅Desta, Habben E⋅Perez Ipiña, Emiliano⋅Parlani, Maria⋅Lee, Se Jong⋅Yankaskas, Christopher L⋅Zhao, Runchen⋅Mistriotis, Panagiotis⋅Wang, Nianchao⋅Gu, Zhizhan⋅Kalab, Petr⋅Friedl, Peter⋅Camley, Brian A and Konstantopoulos, KonstantinosScience advances, vol. 9, (no. 2), pp. eabq6480, January 13, 2023.
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Data from A Procarcinogenic Colon Microbe Promotes Breast Tumorigenesis and Metastatic Progression and Concomitantly Activates Notch and β-Catenin Axes
Data from A Procarcinogenic Colon Microbe Promotes Breast Tumorigenesis and Metastatic Progression and Concomitantly Activates Notch and β-Catenin Axes
Downregulation of YAP Activity Restricts P53 Hyperactivation to Promote Cell Survival in Confinement.Hemmati, Farnaz⋅Hemmati, Farnaz⋅Akinpelu, Ayuba⋅Akinpelu, Ayuba⋅Song, Jiyeon⋅Song, Jiyeon⋅Amiri, Farshad⋅Amiri, Farshad⋅McDaniel, Anya⋅McDaniel, Anya⋅McMurray, Collins⋅McMurray, Collins⋅Afthinos, Alexandros⋅Afthinos, Alexandros⋅Andreadis, Stelios T⋅Andreadis, Stelios T⋅Aitken, Andrew V⋅Aitken, Andrew V⋅Biancardi, Vinicia C⋅Biancardi, Vinicia C⋅Gerecht, Sharon⋅Gerecht, Sharon⋅Mistriotis, Panagiotis and Mistriotis, PanagiotisAdvanced science (Weinheim, Baden-Wurttemberg, Germany), pp. e2302228, June 2, 2023.
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Metronomic Administration of Topotecan Alone and in Combination with Docetaxel Inhibits Epithelial-mesenchymal Transition in Aggressive Variant Prostate Cancers.Mitra Ghosh, Taraswi⋅Mazumder, Suman⋅Davis, Joshua⋅Yadav, Jyoti⋅Akinpelu, Ayuba⋅Alnaim, Ahmed⋅Kumar, Harish⋅Waliagha, Razan⋅Church Bird, Allison E⋅Rais-Bahrami, Soroush⋅Bird, R Curtis⋅Mistriotis, Panagiotis⋅Mishra, Amarjit⋅Yates, Clayton C⋅Mitra, Amit K and Arnold, Robert DCancer research communications, vol. 3, (no. 7), pp. 1286-1311, July 2023.
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Metronomic Administration of Topotecan Alone and in Combination with Docetaxel Inhibits Epithelial-mesenchymal Transition in Aggressive Variant Prostate Cancers. Cancer research communications
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Supplementary Data from A Procarcinogenic Colon Microbe Promotes Breast Tumorigenesis and Metastatic Progression and Concomitantly Activates Notch and β-Catenin Axes
Supplementary Data from A Procarcinogenic Colon Microbe Promotes Breast Tumorigenesis and Metastatic Progression and Concomitantly Activates Notch and β-Catenin Axes
2022
Extracellular fluid viscosity enhances cell migration and cancer disseminationBera, Kaustav⋅Bera, Kaustav⋅Bera, Kaustav⋅Kiepas, Alexander⋅Kiepas, Alexander⋅Kiepas, Alexander⋅Godet, Inês⋅Godet, Inês⋅Godet, Inês⋅Li, Yizeng⋅Li, Yizeng⋅Li, Yizeng⋅Mehta, Pranav⋅Mehta, Pranav⋅Mehta, Pranav⋅Ifemembi, Brent⋅Ifemembi, Brent⋅Ifemembi, Brent⋅Paul, Colin D⋅Paul, Colin D⋅Paul, Colin D⋅Sen, Anindya⋅Sen, Anindya⋅Sen, Anindya⋅Serra, Selma A⋅Serra, Selma A⋅Serra, Selma A⋅Stoletov, Konstantin⋅Stoletov, Konstantin⋅Stoletov, Konstantin⋅Tao, Jiaxiang⋅Tao, Jiaxiang⋅Tao, Jiaxiang⋅Shatkin, Gabriel⋅Shatkin, Gabriel⋅Shatkin, Gabriel⋅Lee, Se J⋅Lee, Se J⋅Lee, Se J⋅Zhang, Yuqi⋅Zhang, Yuqi⋅Zhang, Yuqi⋅Boen, Adrianna⋅Boen, Adrianna⋅Boen, Adrianna⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Gilkes, Daniele M⋅Gilkes, Daniele M⋅Gilkes, Daniele M⋅Lewis, John D⋅Lewis, John D⋅Lewis, John D⋅Fan, Chen-Ming⋅Fan, Chen-Ming⋅Fan, Chen-Ming⋅Feinberg, Andrew P⋅Feinberg, Andrew P⋅Feinberg, Andrew P⋅Valverde, Miguel A⋅Valverde, Miguel A⋅Valverde, Miguel A⋅Sun, Sean X⋅Sun, Sean X⋅Sun, Sean X⋅Konstantopoulos, Konstantinos⋅Konstantopoulos, Konstantinos and Konstantopoulos, KonstantinosNature, vol. 611, (no. 7935), pp. 365-4,373A-373Y, Nov 10, 2022.
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Integrating Pharmacogenomics Data-Driven Computational Drug Prediction with Single-Cell RNAseq to Demonstrate the Efficacy of a NAMPT Inhibitor against Aggressive, Taxane-Resistant, and Stem-like Cells in Lethal Prostate Cancer. Cancers
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Kidney epithelial cells are active mechano-biological fluid pumps. Nature CommunicationsChoudhury, Mohammad Ikbal⋅Li, Yizeng⋅Mistriotis, Panagiotis⋅Vasconcelos, Ana Carina N⋅Dixon, Eryn E⋅Yang, Jing⋅Benson, Morgan⋅Maity, Debonil⋅Walker, Rebecca⋅Martin, Leigha⋅Koroma, Fatima⋅Qian, Feng⋅Konstantopoulos, Konstantinos⋅Woodward, Owen M and Sun, Sean X
Migration and 3D Traction Force Measurements inside Compliant Microchannels.Afthinos, Alexandros⋅Afthinos, Alexandros⋅Bera, Kaustav⋅Bera, Kaustav⋅Chen, Junjie⋅Chen, Junjie⋅Ozcelikkale, Altug⋅Ozcelikkale, Altug⋅Amitrano, Alice⋅Amitrano, Alice⋅Choudhury, Mohammad Ikbal⋅Choudhury, Mohammad Ikbal⋅Huang, Randy⋅Huang, Randy⋅Pachidis, Pavlos⋅Pachidis, Pavlos⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Chen, Yun⋅Chen, Yun⋅Konstantopoulos, Konstantinos and Konstantopoulos, KonstantinosNano letters, vol. 22, (no. 18), pp. 7318-7327, September 28, 2022.
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Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasisZhang, Yuqi⋅Zhang, Yuqi⋅Li, Yizeng⋅Li, Yizeng⋅Thompson, Keyata N.⋅Thompson, Keyata N.⋅Stoletov, Konstantin⋅Stoletov, Konstantin⋅Yuan, Qinling⋅Yuan, Qinling⋅Bera, Kaustav⋅Bera, Kaustav⋅Lee, Se Jong⋅Lee, Se Jong⋅Zhao, Runchen⋅Zhao, Runchen⋅Kiepas, Alexander⋅Kiepas, Alexander⋅Wang, Yao⋅Wang, Yao⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Serra, Selma A.⋅Serra, Selma A.⋅Lewis, John D.⋅Lewis, John D.⋅Valverde, Miguel A.⋅Valverde, Miguel A.⋅Martin, Stuart S.⋅Martin, Stuart S.⋅Sun, Sean X.⋅Sun, Sean X.⋅Konstantopoulos, Konstantinos and Konstantopoulos, KonstantinosNature Communications, vol. 13, (no. 1), 2022.
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2021
A Procarcinogenic Colon Microbe Promotes Breast Tumorigenesis and Metastatic Progression and Concomitantly Activates Notch and β-Catenin Axes. Cancer Discovery
The fluid shear stress sensor TRPM7 regulates tumor cell intravasation. Science AdvancesYankaskas, Christopher L⋅Bera, Kaustav⋅Stoletov, Konstantin⋅Serra, Selma A⋅Carrillo-Garcia, Julia⋅Tuntithavornwat, Soontorn⋅Mistriotis, Panagiotis⋅Lewis, John D⋅Valverde, Miguel A and Konstantopoulos, Konstantinos
Trans-epithelial Fluid Pumping Performance of Renal Epithelial Cells and Mechanics of Cystic ExpansionChoudhury, Mohammad Ikbal⋅Li, Yizeng⋅Mistriotis, Panagiotis⋅Vasconcelos, Ana⋅Dixson, Eryn⋅Yang, Jing⋅Benson, Morgan⋅Maity, Debonil⋅Walker, Rebecca⋅Martin, Leigha⋅Koroma, Fatima⋅Qian, Feng⋅Konstantopoulos, Konstantinos⋅Woodward, Owen and Sun, SeanResearch Square Platform LLC
2020
Dorsoventral polarity directs cell responses to migration track geometries.Wisniewski, Emily O⋅Wisniewski, Emily O⋅Wisniewski, Emily O⋅Wisniewski, Emily O⋅Wisniewski, Emily O⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Bera, Kaustav⋅Bera, Kaustav⋅Bera, Kaustav⋅Bera, Kaustav⋅Bera, Kaustav⋅Law, Robert A⋅Law, Robert A⋅Law, Robert A⋅Law, Robert A⋅Law, Robert A⋅Zhang, Jitao⋅Zhang, Jitao⋅Zhang, Jitao⋅Zhang, Jitao⋅Zhang, Jitao⋅Nikolic, Milos⋅Nikolic, Milos⋅Nikolic, Milos⋅Nikolic, Milos⋅Nikolic, Milos⋅Weiger, Michael⋅Weiger, Michael⋅Weiger, Michael⋅Weiger, Michael⋅Weiger, Michael⋅Parlani, Maria⋅Parlani, Maria⋅Parlani, Maria⋅Parlani, Maria⋅Parlani, Maria⋅Tuntithavornwat, Soontorn⋅Tuntithavornwat, Soontorn⋅Tuntithavornwat, Soontorn⋅Tuntithavornwat, Soontorn⋅Tuntithavornwat, Soontorn⋅Afthinos, Alexandros⋅Afthinos, Alexandros⋅Afthinos, Alexandros⋅Afthinos, Alexandros⋅Afthinos, Alexandros⋅Zhao, Runchen⋅Zhao, Runchen⋅Zhao, Runchen⋅Zhao, Runchen⋅Zhao, Runchen⋅Wirtz, Denis⋅Wirtz, Denis⋅Wirtz, Denis⋅Wirtz, Denis⋅Wirtz, Denis⋅Kalab, Petr⋅Kalab, Petr⋅Kalab, Petr⋅Kalab, Petr⋅Kalab, Petr⋅Scarcelli, Giuliano⋅Scarcelli, Giuliano⋅Scarcelli, Giuliano⋅Scarcelli, Giuliano⋅Scarcelli, Giuliano⋅Friedl, Peter⋅Friedl, Peter⋅Friedl, Peter⋅Friedl, Peter⋅Friedl, Peter⋅Konstantopoulos, Konstantinos⋅Konstantopoulos, Konstantinos⋅Konstantopoulos, Konstantinos⋅Konstantopoulos, Konstantinos and Konstantopoulos, KonstantinosScience advances, vol. 6, (no. 31), pp. eaba6505, July 2020.
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2019
A Direct Podocalyxin-Dynamin-2 Interaction Regulates Cytoskeletal Dynamics to Promote Migration and Metastasis in Pancreatic Cancer Cells.Wong, Bin Sheng⋅Wong, Bin Sheng⋅Shea, Daniel J⋅Shea, Daniel J⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Tuntithavornwat, Soontorn⋅Tuntithavornwat, Soontorn⋅Law, Robert A⋅Law, Robert A⋅Bieber, Jake M⋅Bieber, Jake M⋅Zheng, Lei⋅Zheng, Lei⋅Konstantopoulos, Konstantinos and Konstantopoulos, KonstantinosCancer research, vol. 79, (no. 11), pp. 2878-2891, June 1, 2019.
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A Direct Podocalyxin-Dynamin-2 Interaction Regulates Cytoskeletal Dynamics to Promote Migration and Metastasis in Pancreatic Cancer Cells. Cancer research
A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens.Yankaskas, Christopher L⋅Yankaskas, Christopher L⋅Yankaskas, Christopher L⋅Yankaskas, Christopher L⋅Thompson, Keyata N⋅Thompson, Keyata N⋅Thompson, Keyata N⋅Thompson, Keyata N⋅Paul, Colin D⋅Paul, Colin D⋅Paul, Colin D⋅Paul, Colin D⋅Vitolo, Michele I⋅Vitolo, Michele I⋅Vitolo, Michele I⋅Vitolo, Michele I⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅⋅Mahendra, Ankit⋅Mahendra, Ankit⋅Mahendra, Ankit⋅⋅Bajpai, Vivek K⋅Bajpai, Vivek K⋅Bajpai, Vivek K⋅Bajpai, Vivek K⋅Shea, Daniel J⋅Shea, Daniel J⋅Shea, Daniel J⋅Shea, Daniel J⋅Manto, Kristen M⋅Manto, Kristen M⋅Manto, Kristen M⋅Manto, Kristen M⋅Chai, Andreas C⋅Chai, Andreas C⋅Chai, Andreas C⋅Chai, Andreas C⋅Varadarajan, Navin⋅Varadarajan, Navin⋅Varadarajan, Navin⋅Kontrogianni-Konstantopoulos, Aikaterini⋅Kontrogianni-Konstantopoulos, Aikaterini⋅Kontrogianni-Konstantopoulos, Aikaterini⋅Martin, Stuart S⋅Martin, Stuart S⋅Martin, Stuart S⋅Martin, Stuart S⋅Konstantopoulos, Konstantinos⋅⋅Konstantopoulos, Konstantinos and Konstantopoulos, KonstantinosNature biomedical engineering, May 6, 2019.
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Cell sensing and decision-making in confinement: The role of TRPM7 in a tug of war between hydraulic pressure and cross-sectional area.Zhao, Runchen⋅Zhao, Runchen⋅Zhao, Runchen⋅Afthinos, Alexandros⋅Afthinos, Alexandros⋅Afthinos, Alexandros⋅Zhu, Tian⋅Zhu, Tian⋅Zhu, Tian⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Li, Yizeng⋅Li, Yizeng⋅Li, Yizeng⋅Serra, Selma A⋅Serra, Selma A⋅Serra, Selma A⋅Zhang, Yuqi⋅Zhang, Yuqi⋅Zhang, Yuqi⋅Yankaskas, Christopher L⋅Yankaskas, Christopher L⋅Yankaskas, Christopher L⋅He, Shuyu⋅He, Shuyu⋅He, Shuyu⋅Valverde, Miguel A⋅Valverde, Miguel A⋅Valverde, Miguel A⋅Sun, Sean X⋅Sun, Sean X⋅Sun, Sean X⋅Konstantopoulos, Konstantinos⋅Konstantopoulos, Konstantinos and Konstantopoulos, KonstantinosScience advances, vol. 5, (no. 7), pp. eaaw7243, July 2019.
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Confinement hinders motility by inducing RhoA-mediated nuclear influx, volume expansion, and blebbing.Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Mistriotis, Panagiotis⋅Wisniewski, Emily O⋅Wisniewski, Emily O⋅Wisniewski, Emily O⋅Bera, Kaustav⋅Bera, Kaustav⋅Bera, Kaustav⋅Keys, Jeremy⋅Keys, Jeremy⋅Keys, Jeremy⋅Li, Yizeng⋅Li, Yizeng⋅Li, Yizeng⋅Tuntithavornwat, Soontorn⋅Tuntithavornwat, Soontorn⋅Tuntithavornwat, Soontorn⋅Law, Robert A⋅Law, Robert A⋅Law, Robert A⋅Perez-Gonzalez, Nicolas A⋅Perez-Gonzalez, Nicolas A⋅Perez-Gonzalez, Nicolas A⋅Erdogmus, Eda⋅Erdogmus, Eda⋅Erdogmus, Eda⋅Zhang, Yuqi⋅Zhang, Yuqi⋅Zhang, Yuqi⋅Zhao, Runchen⋅Zhao, Runchen⋅Zhao, Runchen⋅Sun, Sean X⋅Sun, Sean X⋅Sun, Sean X⋅Kalab, Petr⋅Kalab, Petr⋅Kalab, Petr⋅Lammerding, Jan⋅Lammerding, Jan⋅Lammerding, Jan⋅Konstantopoulos, Konstantinos⋅Konstantopoulos, Konstantinos and Konstantopoulos, KonstantinosThe Journal of cell biology, November 5, 2019.
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