13 Publications
2005
Synthesis of 1,2,3,12a,12b‐Hexahydrocyclopropa‐[1,2‐d]benzo[f]pyrrolo[1,2‐b]isoquinolin‐5,7‐dione related to duocarmycins and anthramycin
Venkatram, Atigadda⋅Venkatram, Atigadda⋅Colley, Tara⋅Colley, Tara⋅Deruiter, Jack⋅Deruiter, Jack⋅Smith, Forrest and Smith, Forrest
Journal of Heterocyclic Chemistry, vol. 42, (no. 2), pp. 301, March 2005. | Journal Article
 
Synthesis of 1,2,3,12a,12b‐Hexahydrocyclopropa[1,2‐d]benzo[f]pyrrolo [1,2‐b]isoquinolin‐5,7‐dione Related to Duocarmycins and Anthramycin
Venkatram, Atigadda⋅Venkatram, Atigadda⋅Colley, Tara⋅Colley, Tara⋅DeRuiter, Jack⋅De Ruiter, Jack⋅Smith, Forrest and Smith, Forrest
ChemInform, vol. 36, (no. 33), pp. no, August 16, 2005. | Journal Article
2004
Systemic and ocular pharmacokinetics ofN-4-benzoylaminophenylsulfonylglycine (BAPSG), a novel aldose reductase inhibitor
Sunkara, Gangadhar⋅Ayalasomayajula, Surya P⋅Rao, Cheruku S⋅Vennerstrom, Jonathan L⋅Kompella, Uday B and De Ruiter, Jack
Journal of Pharmacy and Pharmacology, vol. 56, (no. 3), pp. 358, 2004-03-00. | Journal Article
2002
A Biodegradable Injectable Implant Sustains Systemic and Ocular Delivery of an Aldose Reductase Inhibitor and Ameliorates Biochemical Changes in a Galactose-Fed Rat Model for Diabetic Complications
Aukunuru, Jithan V⋅Aukunuru, Jithan⋅Sunkara, Gangadhar⋅Sunkara, Gangadhar⋅Ayalasomayajula, Surya P⋅Ayalasomayajula, Surya⋅De Ruiter, Jack⋅DeRuiter, Jack⋅Clark, Randall C⋅Clark, Randall⋅Kompella, Uday and Kompella, Uday B
Pharmaceutical Research, vol. 19, (no. 3), pp. 285, 20020300. | Journal Article
2000
In-vitro Hydrolysis, Permeability, and Ocular Uptake of Prodrugs ofN-[4-(Benzoylamino)phenylsulfonyl]glycine, a Novel Aldose Reductase Inhibitor
SUNKARA, GANGADHAR⋅De Ruiter, Jack⋅CLARK, C. RANDALL and KOMPELLA, UDAY B
Journal of Pharmacy and Pharmacology, vol. 52, (no. 9), pp. 1122, 2000-09-00. | Journal Article
1993
Studies on Aldose Reductase Inhibitors from Fungi. II. Moniliformin and Small Ring Analogues
Deruiter, Jack⋅Jacyno, John M⋅Cutler, H. G and Davis, R. Alan
Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 7, (no. 4), pp. 256, 19930000. | Journal Article
1992
Studies on Aldose Reductase Inhibitors from Fungi. I. Citrinin and Related Benzopyran Derivatives
Deruiter, Jack⋅Jacyno, John M⋅Davis, R. Alan and Cutler, Horace G
Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 6, (no. 3), pp. 210, 19920000. | Journal Article
1991
Relative structure-inhibition analyses of the N-benzoyl and N-(phenylsulfonyl) amino acid aldose reductase inhibitors
De Ruiter, Jack⋅Davis, R. Alan⋅Wandrekar, Vinay G and Mayfield, Charles A
Journal of Medicinal Chemistry, vol. 34, (no. 7), pp. 2126, 19910701. | Journal Article
1990
Inhibitory activity and mechanism of inhibition of the N-[[4-benzoylamino)phenyl]sulfonyl]amino acid aldose reductase inhibitors
De Ruiter, Jack and Mayfield, Charles A
Biochemical Pharmacology, vol. 40, (no. 10), pp. 2226, 1990. | Journal Article
1989
Studies of the inhibition of aldose reductase: Evidence for multiple site inhibitor binding
Mayfield, Charles A and Deruiter, Jack
International Journal of Biochemistry, vol. 21, (no. 11), pp. 1285, 1989. | Journal Article
1987
Novel inhibitors of rat lens aldose reductase: N-[[(substituted amino)phenyl]sulfonyl]glycines
Mayfield, Charles A and De Ruiter, Jack
Journal of Medicinal Chemistry, vol. 30, (no. 9), pp. 1598, 19870901. | Journal Article
1986
Design and synthesis of 2-(arylamino)-4(3H)-quinazolinones as novel inhibitors of rat lens aldose reductase
De Ruiter, Jack⋅Brubaker, Abram N⋅Millen, Jane and Riley, Thomas N
Journal of Medicinal Chemistry, vol. 29, (no. 5), pp. 629, 19860501. | Journal Article
 
Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives
De Ruiter, Jack⋅Brubaker, Abram N⋅Whitmer, William L and Stein, James L
Journal of Medicinal Chemistry, vol. 29, (no. 10), pp. 2028, 19861001. | Journal Article