81 Publications (Page 1 of 4)
2023
Extended Exposure Topotecan Significantly Improves Long-Term Drug Sensitivity by Decreasing Malignant Cell Heterogeneity and by Preventing Epithelial–Mesenchymal Transition. International Journal of Molecular Sciences
. | Journal Article
2022
Integrating Pharmacogenomics Data-Driven Computational Drug Prediction with Single-Cell RNAseq to Demonstrate the Efficacy of a NAMPT Inhibitor against Aggressive, Taxane-Resistant, and Stem-like Cells in Lethal Prostate Cancer. Cancers
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Polygenic Ara-C Response Score Identifies Pediatric Patients With Acute Myeloid Leukemia in Need of Chemotherapy AugmentationElsayed, Abdelrahman H.⋅Elsayed, Abdelrahman H⋅Elsayed, Abdelrahman H.⋅Cao, Xueyuan⋅Cao, Xueyuan⋅Cao, Xueyuan⋅Mitra, Amit K.⋅Mitra, Amit K⋅Mitra, Amit K.⋅Wu, Huiyun⋅Wu, Huiyun⋅Wu, Huiyun⋅Raimondi, Susana⋅Raimondi, Susana⋅Raimondi, Susana⋅Cogle, Christopher⋅Cogle, Christopher⋅Cogle, Christopher⋅Al-Mansour, Zeina⋅Al-Mansour, Zeina⋅Al-Mansour, Zeina⋅Ribeiro, Raul C⋅Ribeiro, Raul C.⋅Ribeiro, Raul C.⋅Gamis, Alan⋅Gamis, Alan⋅Gamis, Alan⋅Kolb, Edward Anders⋅Kolb, Edward Anders⋅Kolb, Edward Anders⋅Aplenc, Richard⋅Aplenc, Richard⋅Aplenc, Richard⋅Alonzo, Todd A.⋅Alonzo, Todd A.⋅Alonzo, Todd A⋅Meshinchi, Soheil⋅Meshinchi, Soheil⋅Meshinchi, Soheil⋅Rubnitz, Jeffrey⋅Rubnitz, Jeffrey⋅Rubnitz, Jeffrey⋅Pounds, Stanley⋅Pounds, Stanley⋅Pounds, Stanley⋅Lamba, Jatinder K.⋅Lamba, Jatinder K. and Lamba, Jatinder KJournal of Clinical Oncology.
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Polygenic Ara-C Response Score Identifies Pediatric Patients With Acute Myeloid Leukemia in Need of Chemotherapy Augmentation
Elsayed, Abdelrahman H.⋅Cao, Xueyuan⋅Mitra, Amit K.⋅Wu, Huiyun⋅Raimondi, Susana⋅Cogle, Christopher⋅Al-Mansour, Zeina⋅Ribeiro, Raul C.⋅Gamis, Alan⋅Kolb, Edward Anders⋅Aplenc, Richard⋅Alonzo, Todd A.⋅Meshinchi, Soheil⋅Rubnitz, Jeffrey⋅Pounds, Stanley and Lamba, Jatinder K.
Journal of Clinical Oncology. | Journal Article
Short palate, lung, and nasal epithelial clone 1 (SPLUNC1) level determines steroid-resistant airway inflammation in aging
Jaiswal, Anil Kumar⋅Jaiswal, Anil Kumar⋅Yadav, Jyoti⋅Yadav, Jyoti⋅Makhija, Sangeet⋅Makhija, Sangeet⋅Sandey, Maninder⋅Sandey, Maninder⋅Suryawanshi, Amol⋅Suryawanshi, Amol⋅Mitra, Amit Kumar⋅Mitra, Amit Kumar⋅Mishra, Amarjit and Mishra, Amarjit
American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 322, pp. L102–L115. | Journal Article
2021
Identification and Characterization of Key Differentially Expressed Genes Associated With Metronomic Dosing of Topotecan in Human Prostate CancerGhosh, Taraswi Mitra⋅Mitra Ghosh, Taraswi⋅White, Jason⋅White, Jason⋅Davis, Joshua⋅Davis, Joshua⋅Mazumder, Suman⋅Mazumder, Suman⋅Kansom, Teeratas⋅Kansom, Teeratas⋅Skarupa, Elena⋅Skarupa, Elena⋅Barnett, Grafton S.⋅Barnett, Grafton S.⋅Piazza, Gary A.⋅Piazza, Gary A.⋅Bird, R. Curtis⋅Bird, R. Curtis⋅Mitra, Amit K.⋅Mitra, Amit K.⋅Yates, Clayton⋅Yates, Clayton⋅Cummings, Brian S.⋅Cummings, Brian S.⋅Arnold, Robert D. and Arnold, Robert D.Frontiers in Pharmacology, vol. 12.
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Irg1/itaconate metabolic pathway is a crucial determinant of dendritic cells immune-priming function and contributes to resolute allergen-induced airway inflammation
Jaiswal, Anil Kumar⋅Yadav, Jyoti⋅Makhija, Sangeet⋅Mazumder, Suman⋅Mitra, Amit Kumar⋅Suryawanshi, Amol⋅Sandey, Maninder and Mishra, Amarjit
Mucosal Immunology. | Journal Article
Outcomes of COVID-19 in Patients With Cancer: Report From the National COVID Cohort Collaborative (N3C).Sharafeldin, Noha⋅Sharafeldin, Noha⋅Sharafeldin, Noha⋅Bates, Benjamin⋅Bates, Benjamin⋅Bates, Benjamin⋅Song, Qianqian⋅Song, Qianqian⋅Song, Qianqian⋅Madhira, Vithal⋅Madhira, Vithal⋅Madhira, Vithal⋅Yan, Yao⋅Yan, Yao⋅Yan, Yao⋅Dong, Sharlene⋅Dong, Sharlene⋅Dong, Sharlene⋅Lee, Eileen⋅Lee, Eileen⋅Lee, Eileen⋅Kuhrt, Nathaniel⋅Kuhrt, Nathaniel⋅Kuhrt, Nathaniel⋅Shao, Yu Raymond⋅Shao, Yu Raymond⋅Shao, Yu Raymond⋅Liu, Feifan⋅Liu, Feifan⋅Liu, Feifan⋅Bergquist, Timothy⋅Bergquist, Timothy⋅Bergquist, Timothy⋅Guinney, Justin⋅Guinney, Justin⋅Guinney, Justin⋅Su, Jing⋅Su, Jing⋅Su, Jing⋅Topaloglu, Umit⋅Topaloglu, Umit and Topaloglu, UmitJournal of clinical oncology : official journal of the American Society of Clinical Oncology.
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The Andrographolide analogue 3A.1 synergizes with Taxane derivatives in aggressive metastatic prostate cancers by upregulation of Heat Shock proteins and downregulation of MAT2A-mediated cell migration and invasionGhosh, Taraswi Mitra⋅Mitra Ghosh, Taraswi⋅Kansom, Teeratas⋅Kansom, Teeratas⋅Mazumder, Suman⋅Mazumder, Suman⋅Davis, Joshua⋅Davis, Joshua⋅Alnaim, Ahmed S⋅Alnaim, Ahmed S⋅Jasper, Shanese L⋅Jasper, Shanese L⋅Zhang, Chu⋅Zhang, Chu⋅Bird, Aedan⋅Bird, Aedan⋅Opanasopit, Praneet⋅Opanasopit, Praneet⋅Mitra, Amit Kumar⋅Mitra, Amit Kumar⋅Arnold, Robert D and Arnold, Robert DJournal of Pharmacology and Experimental Therapeutics, pp. JPET–AR–2021–000898.
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2020
In vitro and ex vivo gene expression profiling reveals differential kinetic response of HSPs and UPR genes is associated with PI resistance in multiple myeloma.Mitra, Amit K⋅Mitra, Amit K⋅Mitra, Amit Kumar⋅Kumar, Harish⋅Kumar, Harish⋅Kumar, Harish⋅Ramakrishnan, Vijay⋅Chen, Li⋅Chen, Li⋅Chen, Li⋅Baughn, Linda⋅Baughn, Linda⋅Baughn, Linda⋅Kumar, Shaji⋅Kumar, Shaji⋅Kumar, Shaji⋅Vincent, Rajkumar S⋅Vincent, Rajkumar S⋅Rajkumar, S Vincent⋅Van Ness, Brian G⋅ and Blood cancer journal, vol. 10, pp. 78.
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2019
Association of Schizophrenia Risk with Disordered Niacin Metabolism in an Indian Genome-wide Association StudyPeriyasamy, S.⋅Periyasamy, S.⋅Periyasamy, Sathish⋅Periyasamy, Sathish⋅Periyasamy, Sathish⋅Periyasamy, S.⋅Periyasamy, Sathish⋅Periyasamy, Sathish⋅John, Sujit⋅John, Sujit⋅John, S.⋅John, Sujit⋅John, S.⋅John, Sujit⋅John, S.⋅John, Sujit⋅Padmavati, Raman⋅Padmavati, Raman⋅Padmavati, R.⋅Padmavati, Raman⋅Padmavati, Raman⋅Padmavati, Raman⋅Padmavati, R.⋅Padmavati, R.⋅Rajendren, Preeti⋅Rajendren, Preeti⋅Rajendren, P.⋅Rajendren, Preeti⋅Rajendren, P.⋅Rajendren, Preeti⋅Rajendren, P.⋅Rajendren, Preeti⋅Thirunavukkarasu, Priyadarshini⋅Thirunavukkarasu, P.⋅Thirunavukkarasu, Priyadarshini⋅Thirunavukkarasu, Priyadarshini⋅Thirunavukkarasu, Priyadarshini⋅Thirunavukkarasu, P.⋅Thirunavukkarasu, P.⋅Thirunavukkarasu, Priyadarshini⋅Gratten, Jake⋅Gratten, Jacob⋅Gratten, Jacob⋅Gratten, Jacob⋅Gratten, Jacob⋅Gratten, J.⋅Gratten, J.⋅Gratten, J.⋅Vinkhuyzen, A.⋅Vinkhuyzen, Anna⋅Vinkhuyzen, Anna⋅Vinkhuyzen, A.⋅Vinkhuyzen, Anna⋅Vinkhuyzen, Anna⋅Vinkhuyzen, A.⋅Vinkhuyzen, Anna⋅McRae, Allan⋅McRae, Allan⋅McRae, A.⋅McRae, A.⋅McRae, Allan⋅Mc Rae, Allan⋅McRae, A.⋅McRae, Allan⋅Holliday, Elizabeth⋅Holliday, E.G.⋅Holliday, E.G.⋅Holliday, Elizabeth G⋅Holliday, Elizabeth G.⋅Holliday, Elizabeth G⋅Holliday, E.G.⋅Nyholt, Dale⋅Nyholt, Dale R.⋅Nyholt, D.R.⋅Nyholt, Dale R⋅Nyholt, D.R.⋅Nyholt, Dale R⋅Nyholt, D.R.⋅Nancarrow, D.⋅Nancarrow, Derek⋅Nancarrow, D.⋅Nancarrow, Derek⋅Nancarrow, Derek⋅Nancarrow, D.⋅Brown, Matt⋅others⋅Bakshi, A.⋅Bakshi, Andrew⋅Bakshi, A.⋅Bakshi, A.⋅Bakshi, Andrew⋅other⋅Bakshi, Andrew⋅Hemani, G.⋅Hemani, Gibran⋅Hemani, G.⋅Hemani, G.⋅Hemani, Gibran⋅Hemani, Gibran⋅Nertney, D.⋅Nertney, Deborah⋅Nertney, Deborah⋅Nertney, D.⋅Nertney, D.⋅Nertney, Deborah⋅Smith, H.⋅Smith, Heather⋅Smith, H.⋅Smith, Heather⋅Smith, H.⋅Smith, Heather⋅Filippich, Cheryl⋅Filippich, C.⋅Filippich, C.⋅Filippich, Cheryl⋅Filippich, C.⋅Filippich, Cheryl⋅Patel, Kalpana⋅Patel, Kalpana⋅Patel, K.⋅Patel, Kalpana⋅Patel, K.⋅Patel, K.⋅Fowdar, Javed⋅Fowdar, Javed⋅Fowdar, J.⋅Fowdar, Javed⋅Fowdar, J.⋅Fowdar, J.⋅McLean, Duncan⋅McLean, D.⋅McLean, D.⋅McLean, Duncan⋅McLean, Duncan⋅McLean, D.⋅Tirupati, Srinivasan⋅Tirupati, S.⋅Tirupati, S.⋅Tirupati, Srinivasan⋅Tirupati, S.⋅Tirupati, Srinivasan⋅Nagasundaram, Arunkumar⋅Nagasundaram, A.⋅Nagasundaram, A.⋅Nagasundaram, A.⋅Nagasundaram, Arunkumar⋅Nagasundaram, Arunkumar⋅Gundugurti, P.R.⋅Gundugurti, Prasad Rao⋅Gundugurti, P.R.⋅Gundugurti, P.R.⋅Gundugurti, Prasad Rao⋅Gundugurti, Prasad Rao⋅Selvaraj, K.⋅Selvaraj, Krishnamurthy⋅Selvaraj, Krishnamurthy⋅Selvaraj, Krishnamurthy⋅Selvaraj, K.⋅Selvaraj, K.⋅Jegadeesan, Jayaprakash⋅Jegadeesan, J.⋅Jegadeesan, Jayaprakash⋅Jegadeesan, Jayaprakash⋅Jegadeesan, J.⋅Jegadeesan, J.⋅Jorde, L.B.⋅Jorde, Lynn B.⋅Jorde, L.B.⋅Jorde, Lynn B⋅Jorde, L.B.⋅Wray, Naomi R⋅Wray, N.R.⋅Wray, N.R.⋅Wray, Naomi R.⋅Wray, N.R.⋅Brown, M.A.⋅Brown, Matthew A⋅Brown, Matthew A.⋅Brown, M.A.⋅Brown, M.A.⋅Suetani, Rachel⋅Suetani, R.⋅Suetani, Rachel⋅Suetani, Rachel⋅Suetani, R.⋅Suetani, R.⋅Giacomotto, Jean⋅Giacomotto, Jean⋅Giacomotto, J.⋅Giacomotto, J.⋅Giacomotto, J.⋅Thara, R.⋅Thara, R.⋅Thara, R.⋅Thara, Rangaswamy⋅Thara, Rangaswamy⋅Thara, Rangaswamy⋅Mowry, Bryan J.⋅Mowry, B.J.⋅Mowry, B.J.⋅Mowry, Bryan J⋅Mowry, B.J.⋅Consortium, I.G.V. and Consortium, I.G.V.JAMA Psychiatry, vol. 76, pp. 1026-1034.
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Identification of a de novo FOXP1 mutation and incidental discovery of inherited genetic variants contributing to a case of autism spectrum disorder and epilepsyJay, Kristy⋅Jay, K.⋅Mitra, Amit⋅Mitra, A.⋅Harding, T.⋅Harding, Taylor⋅Matthes, D.⋅Matthes, David⋅Van Ness, Brian and Van Ness, B.Molecular Genetics and Genomic Medicine, vol. 7.
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Molecular signatures of multiple myeloma progression through single cell RNA-Seq
Jang, J.S.⋅Li, Y.⋅Mitra, A.K.⋅Bi, L.⋅Abyzov, A.⋅Wijnen, A.J.⋅Baughn, L.B.⋅Van Ness, B.⋅Rajkumar, V.⋅Kumar, S. and Jen, J.
Blood Cancer Journal, vol. 9. | Journal Article
TIVAN: Tissue-specific cis-eQTL single nucleotide variant annotation and predictionChen, Li⋅Chen, Li⋅Chen, L.⋅Chen, Li⋅Wang, Ye⋅Wang, Ye⋅Wang, Ye⋅Wang, Y.⋅Yao, Bing⋅Yao, Bing⋅Yao, B.⋅Yao, Bing⋅Mitra, Amit⋅Mitra, Amit⋅Mitra, Amit⋅Mitra, A.⋅Wang, Xu⋅Wang, Xu⋅Wang, X.⋅Wang, Xu⋅Qin, Xiao⋅Qin, Xiao⋅Qin, X. and Qin, XiaoBioinformatics, vol. 35.
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VitiVar: A locus specific database of vitiligo associated genes and variations.
Gene: X. | Journal Article
2018
Corrigendum to ?Single cell sequencing reveals heterogeneity within ovarian cancer epithelium and cancer associated stromal cells? [Gyncol. Oncol. 144 (2017) 598?606] (Gynecologic Oncology (2017) 144(3) (598?606), (S0090825817300598) (10.1016/j.ygyno.2017.01.015))Winterhoff, Boris J.⋅Winterhoff, B.J.⋅Winterhoff, Boris J.⋅Maile, M.⋅Maile, Makayla⋅Maile, Makayla⋅Mitra, Amit Kumar⋅Mitra, A.K.⋅Mitra, Amit Kumar⋅Sebe, Attila⋅Sebe, Attila⋅Sebe, A.⋅Bazzaro, Martina⋅Bazzaro, M.⋅Bazzaro, Martina⋅Geller, Melissa A.⋅Geller, M.A.⋅Geller, Melissa A.⋅Abrahante, Juan E.⋅Abrahante, J.E.⋅Abrahante, Juan E.⋅Klein, Molly⋅Klein, M.⋅Klein, Molly⋅Hellweg, R.⋅Hellweg, Raffaele⋅Hellweg, Raffaele⋅Mullany, Sally A.⋅Mullany, Sally A.⋅Mullany, S.A.⋅Beckman, Kenneth⋅Beckman, Kenneth⋅Beckman, K.⋅Daniel, Jerry⋅Daniel, J.⋅Daniel, Jerry⋅Starr, Timothy K.⋅Starr, Timothy K. and Starr, T.K.Gynecologic Oncology, vol. 151, pp. 182-186.
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2017
A de novo splice site mutation in EHMT1 resulting in Kleefstra syndrome with pharmacogenomics screening and behavior therapy for regressive behaviors
Mitra, A.K.⋅Dodge, J.⋅Van Ness, J.⋅Sokeye, I. and Van Ness, B.
Molecular Genetics and Genomic Medicine, vol. 5, pp. 130-140. | Journal Article
A gene expression signature distinguishes innate response and resistance to proteasome inhibitors in multiple myeloma
Mitra, A.K.⋅Harding, T.⋅Mukherjee, U.K.⋅Jang, J.S.⋅Li, Y.⋅HongZheng, R.⋅Jen, J.⋅Sonneveld, P.⋅Kumar, S.⋅Kuehl, W.M.⋅Rajkumar, V. and Van Ness, B.
Blood cancer journal, vol. 7, pp. e581. | Journal Article
Development of expression-based biomarkers of dasatinib response in hematologic malignancies
Akre, M.K.⋅Mitra, A.⋅Wang, W.⋅Myers, C.L. and Van Ness, B.
Blood Cancer Journal, vol. 7. | Journal Article
Development of expression-based biomarkers of Dasatinib response in hematologic malignanciesAkre, Monica K⋅Mitra, Amit⋅Wang, Wen and Myers, Chad L(pp. 1-5). Dec 2017
Single cell sequencing reveals heterogeneity within ovarian cancer epithelium and cancer associated stromal cellsWinterhoff, B.J.⋅Winterhoff, Boris J⋅Winterhoff, Boris J.⋅Maile, Makayla⋅Maile, Makayla⋅Maile, M.⋅Mitra, Amit Kumar⋅Mitra, A.K.⋅Mitra, Amit Kumar⋅Sebe, Attila⋅Sebe, Attila⋅Sebe, A.⋅Bazzaro, M.⋅Bazzaro, Martina⋅Bazzaro, Martina⋅Geller, Melissa A⋅Geller, M.A.⋅Geller, Melissa A.⋅Abrahante, Juan E⋅Abrahante, Juan E.⋅Abrahante, J.E.⋅Klein, Molly⋅Klein, Molly⋅Klein, M.⋅Hellweg, R.⋅Hellweg, Raffaele⋅Hellweg, Raffaele⋅Mullany, S.A.⋅Mullany, Sally A⋅Mullany, Sally A.⋅Beckman, K.⋅Beckman, Kenneth⋅Beckman, Kenneth⋅Daniel, J.⋅Daniel, Jerry⋅Daniel, Jerry⋅Starr, Timothy K⋅Starr, T.K. and Starr, Timothy K.Gynecologic Oncology, vol. 144.
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2016
Fine-mapping of 18q21.1 locus identifies single nucleotide polymorphisms associated with nonsyndromic cleft lip with or without cleft palate
Mitra, A.K.⋅Stessman, H.A.F.⋅Schaefer, R.J.⋅Wang, W.⋅Myers, C.L.⋅Van Ness, B.G. and Beiraghi, S.
Frontiers in Genetics, vol. 7. | Journal Article
Genetic contribution of CYP1A1 variant on treatment outcome in epilepsy patients: a functional and interethnic perspective.
Talwar, P.⋅Kanojia, N.⋅Mahendru, S.⋅Baghel, R.⋅Grover, S.⋅Arora, G.⋅Grewal, G. K.⋅Parween, S.⋅Srivastava, A.⋅Singh, M.⋅Vig, S.⋅Kushwaha, S.⋅Sharma, S.⋅Bala, K.⋅Kukreti, S. and Kukreti, R.
The pharmacogenomics journal. | Journal Article
Phenotypic and functional characterization of a bortezomib-resistant multiple myeloma cell line by flow and mass cytometry
Baughn, L.B.⋅Sachs, Z.⋅Noble-Orcutt, K.E.⋅Mitra, A.⋅Van Ness, B.G. and Linden, M.A.
Leukemia and Lymphoma. | Journal Article
Single-cell analysis of targeted transcriptome predicts drug sensitivity of single cells within human myeloma tumors
Mitra, A.K.⋅Mukherjee, U.K.⋅Harding, T.⋅Jang, J.S.⋅Stessman, H.⋅Li, Y.⋅Abyzov, A.⋅Jen, J.⋅Kumar, S.⋅Rajkumar, V. and Van Ness, B.
Leukemia, vol. 30, pp. 1094-1102. | Journal Article