Profile - Publications | Scholars@Auburn

22 Publications

2016

AAV-mediated gene delivery attenuates neuroinflammation in feline Sandhoff disease.
Bradbury, Allison M⋅Bradbury, Allison⋅Bradbury, Allison⋅Bradbury, Allison⋅Peterson, Tiffany⋅Peterson, Tiffany A⋅Peterson, Tiffany⋅Peterson, Tiffany⋅Gross, Amanda⋅Gross, Amanda⋅Gross, Amanda ...more »
Neuroscience, October 26, 2016. | Journal Article

2015

AAV-mediated gene delivery in a feline model of Sandhoff disease corrects lysosomal storage in the central nervous system.
Rockwell, Hannah E⋅Rockwell, Hannah E⋅McCurdy, Victoria J⋅McCurdy, Victoria J⋅Eaton, Samuel C⋅Eaton, Samuel C⋅Wilson, Diane U⋅Wilson, Diane U⋅Johnson, Aime K⋅Johnson, Aime K⋅Randle, Ashley N ...more »
ASN neuro, vol. 7, (no. 2). | Journal Article

Biomarkers for disease progression and AAV therapeutic efficacy in feline Sandhoff disease.
Bradbury, Allison M⋅Bradbury, Allison M⋅Gray-Edwards, Heather L⋅Gray-Edwards, Heather L⋅Shirley, Jamie L⋅Shirley, Jamie L⋅McCurdy, Victoria J⋅McCurdy, Victoria J⋅Colaco, Alexandria N⋅Colaco, Alexandria N⋅Randle, Ashley N ...more »
Experimental neurology, vol. 263, pp. 102-112, January 2015. | Journal Article

Mucopolysaccharidosis-like phenotype in feline Sandhoff disease and partial correction after AAV gene therapy.
Gray-Edwards, Heather L⋅Gray-Edwards, Heather L⋅Gray-Edwards, Heather L⋅Brunson, Brandon L⋅Brunson, Brandon L⋅Brunson, Brandon L⋅Holland, Merrilee⋅Holland, Merrilee⋅Holland, Merrilee⋅Hespel, Adrien-Maxence⋅Hespel, Adrien Maxence ...more »
Molecular genetics and metabolism, vol. 116, (no. 1-2), pp. 80-87. | Journal Article

2014

Ganglioside storage diseases: on the road to management.
Seyfried, Thomas N⋅Rockwell, Hannah E⋅Heinecke, Karie A⋅Martin, Douglas R and Sena-Esteves, Miguel
Advances in neurobiology, vol. 9, pp. 485-499, 2014. | Journal Article

High resolution MRI anatomy of the cat brain at 3Tesla
Gray-Edwards, Heather L⋅Gray-Edwards, Heather L⋅Salibi, Nouha⋅Salibi, Nouha⋅Josephson, Eleanor M⋅Josephson, Eleanor M⋅Hudson, Judith A⋅Hudson, Judith A⋅Cox, Nancy R⋅Cox, Nancy R⋅Randle, Ashley N ...more »
Journal of Neuroscience Methods, vol. 227, pp. 17, 2014-04-30. | Journal Article

Recent advances in delivery through the blood-brain barrier.
Larsen, Jessica M⋅Martin, Douglas R and Byrne, Mark E
Current topics in medicinal chemistry, vol. 14, (no. 9), pp. 1148-1160, 2014. | Journal Article

Sustained normalization of neurological disease after intracranial gene therapy in a feline model.
McCurdy, Victoria J⋅McCurdy, Victoria J⋅Johnson, Aime K⋅Johnson, Aime K⋅Gray-Edwards, Heather L⋅Gray-Edwards, Heather L⋅Randle, Ashley N⋅Randle, Ashley N⋅Brunson, Brandon L⋅Brunson, Brandon L⋅Morrison, Nancy E ...more »
Science translational medicine, vol. 6, (no. 231), pp. 231ra48, 2014/Apr/9. | Journal Article

2013

Therapeutic response in feline sandhoff disease despite immunity to intracranial gene therapy.
Bradbury, Allison M⋅Bradbury, Allison M⋅Bradbury, Allison M⋅Bradbury, Allison M⋅Cochran, J Nicholas⋅Cochran, J N⋅Cochran, J N⋅Cochran, J N⋅Mccurdy, Victoria J⋅McCurdy, Victoria J⋅McCurdy, Victoria J ...more »
Molecular therapy : the journal of the American Society of Gene Therapy, vol. 21, (no. 7), pp. 1306-15, 2013/Jul. | Journal Article

2012

Evaluation of N-nonyl-deoxygalactonojirimycin as a pharmacological chaperone for human GM1 gangliosidosis leads to identification of a feline model suitable for testing enzyme enhancement therapy
Rigat, Brigitte A⋅Tropak, Michael B⋅Buttner, Justin⋅Crushell, Ellen⋅Benedict, Daphne⋅Callahan, John W⋅Martin, Douglas R and Mahuran, Don J
Molecular Genetics and Metabolism, vol. 107, (no. 1-2), pp. 203-212, 2012. | Journal Article

2009

Comparative analysis of brain lipids in mice, cats, and humans with Sandhoff disease.
Baek, Rena C⋅Martin, Douglas R⋅Cox, Nancy R and Seyfried, Thomas N
Lipids, vol. 44, (no. 3), pp. 197-205, 2009/Mar. | Journal Article

Neural stem/progenitor cells modulate immune responses by suppressing T lymphocytes with nitric oxide and prostaglandin E2
Wang, Lei⋅Shi, Jishu⋅van Ginkel, Frederik W⋅Lan, Liqiong⋅Niemeyer, Glenn⋅Martin, Douglas R⋅Snyder, Evan Y and Cox, Nancy R
Experimental Neurology, vol. 216, (no. 1), pp. 177-183, 2009. | Journal Article

Neurodegenerative lysosomal storage disease in European Burmese cats with hexosaminidase beta-subunit deficiency.
Bradbury, Allison M⋅Morrison, Nancy E⋅Hwang, Misako⋅Cox, Nancy R⋅Baker, Henry J and Martin, Douglas R
Molecular genetics and metabolism, vol. 97, (no. 1), pp. 53-9, 2009/May. | Journal Article

Neurodegenerative lysosomal storage disease in European Burmese cats with hexosaminidase b-subunit deficiency
Bradbury, Allison M⋅Morrison, Nancy E⋅Hwang, Misako⋅Cox, Nancy R⋅Baker, Henry J and Martin, Douglas R
Molecular Genetics and Metabolism, vol. 97, (no. 1), pp. 53-59, 2009. | Journal Article

2008

Generation and characterization of recombinant feline [beta]-galactosidase for preclinical enzyme replacement therapy studies in GM1 gangliosidosis
Samoylova, Tatiana I⋅Martin, Douglas R⋅Morrison, Nancy E⋅Hwang, Misako⋅Cochran, Anna M⋅Samoylov, Alexandre M⋅Baker, Henry J and Cox, Nancy R
Metabolic Brain Disease, vol. 23, (no. 2), pp. 161-73, Jun 2008. | Journal Article

Generation and characterization of recombinant feline ^b-galactosidase for preclinical enzyme replacement therapy studies in GM1 gangliosidosis
Samoylova, Tatiana I⋅Martin, Douglas R⋅Morrison, Nancy E⋅Hwang, Misako⋅Cochran, Anna M⋅Samoylov, Alexandre M⋅Baker, Henry J and Cox, Nancy R
Metabolic Brain Disease, vol. 23, (no. 2), pp. 161-173, 2008. | Journal Article

Molecular consequences of the pathogenic mutation in feline GM1 gangliosidosis.
Martin, Douglas R⋅Rigat, Brigitte A⋅Foureman, Polly⋅Varadarajan, G S⋅Hwang, Misako⋅Krum, Barbara K⋅Smith, Bruce F⋅Callahan, John W⋅Mahuran, Don J and Baker, Henry J
Molecular genetics and metabolism, vol. 94, (no. 2), pp. 212-21, 2008/Jun. | Journal Article

2007

12 Gene therapy of feline gangliosidosis with AAV vectors
Martin, Douglas R⋅Baker, Henry J⋅Cox, Nancy R⋅Cachon-Gonzalez, Begona and Cox, Timothy M
Molecular Genetics and Metabolism, vol. 92, (no. 4), pp. p. 14, 2007. | Journal Article

Neural progenitor cell transplantation and imaging in a large animal model.
Wang, Lei⋅Martin, Douglas R⋅Baker, Henry J⋅Zinn, Kurt R⋅Kappes, John C⋅Ding, Haitao⋅Gentry, Atoska S⋅Harper, Scarlett⋅Snyder, Evan Y and Cox, Nancy R
Neuroscience research, vol. 59, (no. 3), pp. 327-40, 2007/Nov. | Journal Article

2005

Mutation of the GM2 activator protein in a feline model of GM2 gangliosidosis.
Martin, Douglas R⋅Cox, Nancy R⋅Morrison, Nancy E⋅Kennamer, David M⋅Peck, Stephanie L⋅Dodson, Arlene N⋅Gentry, Atoska S⋅Griffin, Brenda⋅Rolsma, Mark D and Baker, Henry J
Acta neuropathologica, vol. 110, (no. 5), pp. 443-50, 2005/Nov. | Journal Article

2004

An inversion of 25 base pairs causes feline GM2 gangliosidosis variant.
Martin, Douglas R⋅Krum, Barbara K⋅Varadarajan, G S⋅Hathcock, Terri L⋅Smith, Bruce F and Baker, Henry J
Experimental neurology, vol. 187, (no. 1), pp. 30-7, 2004/May. | Journal Article

2002

Isolation and characterization of multipotential mesenchymal stem cells from feline bone marrow.
Martin, Douglas R⋅Cox, Nancy R⋅Hathcock, Terri L⋅Niemeyer, Glenn P and Baker, Henry J
Experimental hematology, vol. 30, (no. 8), pp. 879-86, 2002/Aug. | Journal Article

Douglas R. Martin Professor