Dr. Smith’s current work focuses on understanding the molecular cascades involved in DMD and developing next-generation oncolytic viral vectors for a variety of cancers.
Of particular interest is understanding and subsequently addressing the cardiac defects seen in this disease.
Dr. Smith’s research program in muscular dystrophies is currently focused on identifying canine models of these diseases and applying novel genetic therapies to their treatment.
Dr. Smith’s current research focuses in two areas of genetic therapy, gene therapies for inherited muscular dystrophies, and genetic approaches to therapy for cancer.
Among the tumors of interest to the laboratory are osteosarcoma, hemangiosarcoma, lymphoma, melanoma, and mammary cancer.
