We are interested in 1) how mRNAs are selected by translational system, and how it leads to the progression of the disease. 2) How molecular machine called ribosome makes proteins with astonishing speed and precision, reading 20 codons per second while making less than 1 mistake in 3000 codons, virtually insuring that no error is ever made.
We are interested in mechanisms and regulation of translation. We are using biochemical and single-molecule methods to understand how ribosomes synthesize proteins and how they are regulated by mRNA, factors, and small molecules.
