54 Publications (Page 1 of 3)
2021
Designing new antitubercular isoniazid derivatives with improved reactivity and membrane trafficking abilities.
de Faria, Catarina FrazãoMoreira, TâniaLopes, PedroCosta, HenriqueKrewall, Jessica RBarton, Callie MSantos, SusanaGoodwin, DouglasMachado, DianaViveiros, MiguelMachuqueiro, Miguel and Martins, Filomena
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, vol. 144, pp. 112362, October 25, 2021. | Journal Article
2018
A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase
Alturki, Mansour SAlturki, M.S.Fuanta, Ngolui ReneFuanta, N.R.Jarrard, Madison AJarrard, M.A.Hobrath, Judith VHobrath, J.V.Goodwin, Douglas CGoodwin, D.C.Rants'o, Thankhoe ARants’o, T.A.Calderón, Angela I and Calderón, A.I.
Bioorganic & Medicinal Chemistry Letters, vol. 28, (no. 4), pp. 808, 2018-02-15. | Journal Article
 
Mechanism of irreversible inhibition of Mycobacterium tuberculosis shikimate kinase by ilimaquinone.
Simithy, JohayraSimithy, J.Fuanta, Ngolui ReneFuanta, N.R.Hobrath, Judith VHobrath, J.V.Kochanowska-Karamyan, AnnaKochanowska-Karamyan, A.Hamann, Mark THamann, M.T.Goodwin, Douglas CGoodwin, D.C.Calderón, Angela I and Calderón, A.I.
Biochimica et biophysica acta, vol. 1866, (no. 5-6), pp. 731-739. | Journal Article
 
Slow-Binding Inhibition of Mycobacterium tuberculosis Shikimate Kinase by Manzamine Alkaloids.
Simithy, JohayraSimithy, J.Fuanta, Ngolui ReneFuanta, N.R.Alturki, MansourAlturki, M.Hobrath, Judith VHobrath, J.V.Wahba, Amir EWahba, A.E.Pina, I.Pina, IvettRath, J.Rath, JnanendraHamann, Mark THamann, M.T.DeRuiter, JackDeruiter, J.Goodwin, Douglas CGoodwin, D.C.Calderón, Angela I and Calderón, A.I.
Biochemistry, July 31, 2018. | Journal Article
2017
A multifaceted approach to identify non-specific enzyme inhibition:Application to Mycobacterium tuberculosis shikimate kinase
Alturki, MansourFuanta, NgoluiJarrard, MadisonHobrath, JudithGoodwin, DouglasRants'o, Thankhoe and Calderón, Angela
2017-12-05. | Journal Article
 
Mutual synergy between catalase and peroxidase activities of the bifunctional enzyme KatG is facilitated by electron hole-hopping within the enzyme
Njuma, Olive JNjuma, Olive JDavis, IanDavis, IanNdontsa, Elizabeth NNdontsa, Elizabeth NKrewall, Jessica RKrewall, Jessica RLiu, AiminLiu, AiminGoodwin, Douglas C and Goodwin, Douglas C
The Journal of biological chemistry, vol. 292, (no. 45), pp. 18421, 2017-11-10. | Journal Article
2015
A role for catalase-peroxidase large loop 2 revealed by deletion mutagenesis: control of active site water and ferric enzyme reactivity.
Kudalkar, Shalley NNjuma, Olive JLi, YongjiangMuldowney, MichelleFuanta, N Rene and Goodwin, Douglas C
Biochemistry, vol. 54, (no. 8), pp. 1648-1662, March 3, 2015. | Journal Article
 
Development of an ESI-LC-MS-based assay for kinetic evaluation of Mycobacterium tuberculosis shikimate kinase activity and inhibition.
Simithy, JohayraSimithy, J.Gill, GobindGill, G.Wang, YuWang, Y.Goodwin, D.C.Goodwin, Douglas CCalderón, Angela I and Calderón, A.I.
Analytical chemistry, vol. 87, (no. 4), pp. 2129-2136, February 17, 2015. | Journal Article
 
Inactivation of myeloperoxidase by benzoic acid hydrazide
Huang, JianshengHuang, JianshengHuang, JianshengSmith, ForrestSmith, ForrestSmith, ForrestPanizzi, Jennifer RPanizzi, Jennifer R.Panizzi, PeterPanizzi, Jennifer RPanizzi, PeterGoodwin, Douglas CGoodwin, Douglas CGoodwin, Douglas C. and Panizzi, Peter
Archives of Biochemistry and Biophysics, vol. 570, pp. 14--22. | Journal Article
 
Plasmodium falciparum Thioredoxin Reductase (PfTrxR) and Its Role as a Target for New Antimalarial Discovery.
McCarty, Sara EMcCarty, S.E.Schellenberger, AmandaSchellenberger, A.Goodwin, Douglas CGoodwin, D.C.Fuanta, Ngolui ReneFuanta, N.R.Tekwani, Babu LTekwani, B.L.Calderón, Angela I and Calderón, A.I.
Molecules (Basel, Switzerland), vol. 20, (no. 6), pp. 11459-11473, 2015. | Journal Article
 
Selective Mycobacterium tuberculosis Shikimate Kinase Inhibitors as Potential Antibacterials.
Gordon, SaraGordon, S.Simithy, J.Simithy, JohayraGoodwin, Douglas CGoodwin, D.C.Calderón, Angela I and Calderón, A.I.
Perspectives in medicinal chemistry, vol. 7, pp. 9-20, 2015. | Journal Article
2014
Catalase in peroxidase clothing: Interdependent cooperation of two cofactors in the catalytic versatility of KatG.
Njuma, Olive JNdontsa, Elizabeth N and Goodwin, Douglas C
Archives of biochemistry and biophysics, vol. 544, pp. 27-39, February 15, 2014. | Journal Article
2013
From Contrastive Rhetoric towards Perceptions of Identity: Written Academic English in Central Mexico
Crawford, TroyMora Pablo, IrasemaGoodwin, Douglas and Lengelin, Martha
Colombian Applied Linguistics Journal, vol. 15, (no. 1), pp. 24, 20130601. | Journal Article
 
Integral role of the I'-helix in the function of the "inactive" C-terminal domain of catalase-peroxidase (KatG).
Wang, Yu and Goodwin, Douglas
Biochimica et biophysica acta, vol. 1834, (no. 1), pp. 362-71, 2013/Jan. | Journal Article
2012
Bone Dielectric Property Variation as a Function of Mineralization at Microwave Frequencies
Meaney, Paul MMeaney, PaulZhou, TianZhou, TianGoodwin, DouglasGoodwin, DouglasGolnabi, AmirGolnabi, AmirAttardo, Elia AAttardo, EliaPaulsen, Keith D and Paulsen, Keith
International journal of biomedical imaging, vol. 2012, pp. 9, 2012. | Journal Article
 
Enhancing the peroxidatic activity of KatG by deletion mutagenesis.
Kudalkar, Shalley NCampbell, Robert ALi, YongjiangVarnado, Cornelius LPrescott, Corey and Goodwin, Douglas
Journal of inorganic biochemistry, vol. 116, pp. 106-15, 2012/Nov. | Journal Article
 
Stimulation of KatG catalase activity by peroxidatic electron donors.
Ndontsa, Elizabeth NMoore, Robert L and Goodwin, Douglas
Archives of biochemistry and biophysics, vol. 525, (no. 2), pp. 215-22, 2012/Sep/15. | Journal Article
2011
An Improvised Mechanism for H2O2 Disproportionation Based on an Old Enzyme Scaffold
Ndontsa, Elizabeth N and Goodwin, Douglas C
Free Radical Biology and Medicine, vol. 51, pp. S148, 2011-11-00. | Journal Article
 
Contribution of An “Inactive” Domain To Rapid H2O2Decomposition by KatG
Wang, Yu and Goodwin, Douglas
Free Radical Biology and Medicine, vol. 51, pp. S151, 2011-11-00. | Journal Article
 
Essential Role of Distant Interdomain Interactions in H2O2 Decomposition by Catalase-Peroxidases
Duan, Haijun and Goodwin, Douglas C
Free Radical Biology and Medicine, vol. 51, pp. S144, 2011-11-00. | Journal Article
 
Mesohaem substitution reveals how haem electronic properties can influence the kinetic and catalytic parameters of neuronal NO synthase.
Tejero Bravo, JesusTejero, JesúsBiswas, AshisHaque, Mohammad MWang, Zhi QiangHemann, CraigVarnado, Cornelius LNovince, ZacharyHille, Charles RussellGoodwin, Douglas and Stuehr, Dennis J
The Biochemical journal, vol. 433, (no. 1), pp. 163-74, 2011/Jan/1. | Journal Article
 
Students and Teachers' Reasons for Using the First Language Within the Foreign Language Classroom (French and English) in Central Mexico
Mora Pablo, IrasemaLengeling, M. MarthaRubio Zenil, BuenaventuraCrawford, Troy and Goodwin, Douglas
Profile Issues in Teachers` Professional Development, vol. 13, (no. 2), pp. 129, 20111001. | Journal Article
 
Students and teachers' reasons for using the first language within the foreign language classroom (French and English) in Central Mexico/Razones de alumnos y maestros sobre el uso de la primera lengua en el salon de lenguas extranjeras en el centro de Mexico
Pablo, IrasemaLengeling, M.Zenil, BuenaventuraCrawford, Troy and Goodwin, Douglas
Revista PROFILE Issues in Teachers' Professional Development, vol. 13, (no. 2), pp. 113, 20111001. | Journal Article
2008
Substitution of strictly conserved Y111 in catalase-peroxidases: Impact of remote interdomain contacts on active site structure and catalytic performance.
Moore, Robert LCook, Carma OWilliams, Rachel and Goodwin, Douglas
Journal of inorganic biochemistry, vol. 102, (no. 9), pp. 1819-24, 2008/Sep. | Journal Article
 
The kinetic properties producing the perfunctory pH profiles of catalase-peroxidases.
Moore, Robert LPowell, Luke J and Goodwin, Douglas
Biochimica et biophysica acta, vol. 1784, (no. 6), pp. 900-7, 2008/Jun. | Journal Article