Expertise:
- Role of mitochondrial DNA integrity in lung cell survival
My research interest concentrates on both - damaging and signaling - sides of free radical's action in cells. Current topics include:
- Oxidative stress and its influence on genome stability
- Mitochondrial DNA as a sentinel molecule, severity and persistence of damage to which determines the cell viability
- Oxidative mitochondrial DNA damage and its role in initiation of endothelial cell apoptosis caused by oxidative stress
- Role of controlled ROS-mediated oxidative DNA damage and repair in normal transcriptional regulation
- Effective biomarkers of oxidative stress
