8 Publications
2023
Acute PDE4 Inhibition Induces a Transient Increase in Blood Glucose in Mice
Irelan, Daniel⋅Irelan, Daniel⋅Boyd, Abigail⋅Boyd, Abigail⋅Fiedler, Edward⋅Lochmaier, Peter⋅McDonough, Will⋅Aragon, Ileana V⋅Rachek, Lyudmila⋅Richter, Wito and Richter, Wito
International Journal of Molecular Sciences, vol. 24, (no. 4), 2023. | Journal Article
2022
Non-Selective PDE4 Inhibition Induces a Rapid and Transient Decrease of Serum Potassium in Mice
Boyd, Abigail⋅Boyd, Abigail⋅Lochmaier, Peter⋅Lochmaier, Peter⋅Irelan, Daniel⋅Irelan, Daniel⋅Fiedler, Edward⋅Fouty, Brian⋅Richter, Wito and Richter, Wito
Biology, vol. 11, (no. 11), 2022. | Journal Article
2021
Ablation of PDE4B protects from Pseudomonas aeruginosa-induced acute lung injury in mice by ameliorating the cytostorm and associated hypothermia.
Abou Saleh, Lina⋅Boyd, Abigail⋅Aragon, Ileana V⋅Koloteva, Anna⋅Spadafora, Domenico⋅Mneimneh, Wadad⋅Barrington, Robert A and Richter, Wito
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol. 35, (no. 9), pp. e21797, September 2021. | Journal Article
 
Assessment of PDE4 Inhibitor-Induced Hypothermia as a Correlate of Nausea in Mice.
Boyd, Abigail⋅Aragon, Ileana V⋅Rich, Justin⋅McDonough, Will⋅Oditt, Marianna⋅Irelan, Daniel⋅Fiedler, Edward⋅Abou Saleh, Lina and Richter, Wito
Biology, vol. 10, (no. 12), December 20, 2021. | Journal Article
 
Inhibition of cAMP-phosphodiesterase 4 (PDE4) potentiates the anesthetic effects of Isoflurane in mice.
Aragon, Ileana V⋅Boyd, Abigail⋅Abou Saleh, Lina⋅Rich, Justin⋅McDonough, Will⋅Koloteva, Anna and Richter, Wito
Biochemical pharmacology, pp. 114477, February 17, 2021. | Journal Article
2020
Inhibition of type 4 cAMP-phosphodiesterases (PDE4s) in mice induces hypothermia via effects on behavioral and central autonomous thermoregulation.
McDonough, Will⋅Rich, Justin⋅Aragon, Ileana V⋅Abou Saleh, Lina⋅Boyd, Abigail⋅Richter, Aris⋅Koloteva, Anna and Richter, Wito
Biochemical pharmacology, vol. 180, pp. 114158, October 2020. | Journal Article
 
PAN-selective inhibition of cAMP-phosphodiesterase 4 (PDE4) induces gastroparesis in mice.
McDonough, Will⋅Aragon, Ileana V⋅Rich, Justin⋅Murphy, James M⋅Abou Saleh, Lina⋅Boyd, Abigail⋅Koloteva, Anna and Richter, Wito
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol. 34, (no. 9), pp. 12533-12548, September 2020. | Journal Article
2014
Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes.
Haj Slimane, Zeineb⋅Bedioune, Ibrahim⋅Lechêne, Patrick⋅Varin, Audrey⋅Lefebvre, Florence⋅Mateo, Philippe⋅Domergue-Dupont, Valérie⋅Dewenter, Matthias⋅Richter, Wito⋅Conti, Marco⋅El-Armouche, Ali⋅Zhang, Jin⋅Fischmeister, Rodolphe and Vandecasteele, Grégoire
Cardiovascular research, vol. 102, (no. 1), pp. 97-106, April 1, 2014. | Journal Article