8 Publications
2016
Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.
Chattopadhyay, Debasish⋅Chattopadhyay, Debasish⋅Chattopadhyay, Debasish⋅Swingle, Mark R⋅Swingle, Mark R⋅Swingle, Mark R⋅Salter, Edward A⋅Salter, Edward A⋅Salter, Edward A⋅Wood, Eric⋅Wood, Eric⋅Wood, Eric⋅D'Arcy, Brandon⋅D'Arcy, Brandon⋅D'Arcy, Brandon⋅Zivanov, Catherine⋅Zivanov, Catherine⋅Zivanov, Catherine⋅Abney, Kevin⋅Abney, Kevin⋅Abney, Kevin⋅Musiyenko, Alla⋅Musiyenko, Alla⋅Musiyenko, Alla⋅Rusin, Scott F⋅Rusin, Scott F⋅Rusin, Scott F⋅Kettenbach, Arminja⋅Kettenbach, Arminja⋅Kettenbach, Arminja⋅Yet, Larry⋅Yet, Larry⋅Yet, Larry⋅Schroeder, Chad E⋅Schroeder, Chad E⋅Schroeder, Chad E⋅Golden, Jennifer E⋅Golden, Jennifer E⋅Golden, Jennifer E⋅Dunham, Wade H⋅Dunham, Wade H⋅Dunham, Wade H⋅Gingras, Anne-Claude⋅Gingras, Anne-Claude⋅Gingras, Anne-Claude⋅Banerjee, Surajit⋅Banerjee, Surajit⋅Banerjee, Surajit⋅Forbes, David⋅Forbes, David⋅Forbes, David⋅Wierzbicki, Andrzej⋅Wierzbicki, Andrzej⋅Wierzbicki, Andrzej⋅Honkanen, Richard E⋅Honkanen, Richard E and Honkanen, Richard E
Biochemical pharmacology, vol. 109, pp. 14-26, June 1, 2016. | Journal Article
2015
Discovery and hit-to-lead optimization of 2,6-diaminopyrimidine inhibitors of interleukin-1 receptor-associated kinase 4.
McElroy, William T⋅Michael Seganish, W⋅Jason Herr, R⋅Harding, James⋅Yang, Jinhai⋅Yet, Larry⋅Komanduri, Venukrishnan⋅Prakash, Koraboina Chandra⋅Lavey, Brian⋅Tulshian, Deen⋅Greenlee, William J⋅Sondey, Christopher⋅Fischmann, Thierry O and Niu, Xiaoda
Bioorganic & medicinal chemistry letters, vol. 25, (no. 9), pp. 1836-1841, May 1, 2015. | Journal Article
 
Initial optimization and series evolution of diaminopyrimidine inhibitors of interleukin-1 receptor associated kinase 4.
Seganish, W Michael⋅McElroy, William T⋅Herr, R Jason⋅Brumfield, Stephanie⋅Greenlee, William J⋅Harding, James⋅Komanduri, Venukrishnan⋅Matasi, Julius⋅Prakash, Koraboina Chandra⋅Tulshian, Deen⋅Yang, Jinhai⋅Yet, Larry⋅Devito, Kristine⋅Fossetta, James⋅Garlisi, Charles G⋅Lundell, Daniel⋅Niu, Xiaoda and Sondey, Christopher
Bioorganic & medicinal chemistry letters, vol. 25, (no. 16), pp. 3203-3207, August 15, 2015. | Journal Article
 
Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity.
Li, N⋅Lee, K⋅Xi, Y⋅Zhu, B⋅Gary, B D⋅Ramírez-Alcántara, V⋅Gurpinar, E⋅Canzoneri, J C⋅Fajardo, A⋅Sigler, S⋅Piazza, J T⋅Chen, X⋅Andrews, J⋅Thomas, M⋅Lu, W⋅Li, Y⋅Laan, D J⋅Moyer, M P⋅Russo, S⋅Eberhardt, B T⋅Yet, L⋅Keeton, A B⋅Grizzle, W E and Piazza, G A
Oncogene, vol. 34, (no. 12), pp. 1499-1509, March 19, 2015. | Journal Article
 
Progress in the development of fatty acid synthase inhibitors as anticancer targets.
Mullen, Genevieve E and Yet, Larry
Bioorganic & medicinal chemistry letters, vol. 25, (no. 20), pp. 4363-4369, October 15, 2015. | Journal Article
2003
Chemistry and biology of salicylihalamide a and related compounds.
Yet, Larry
Chemical reviews, vol. 103, (no. 11), pp. 4283-4306, November 2003. | Journal Article
2001
Recent Developments in Catalytic Asymmetric Strecker-Type Reactions.
Yet, Larry
Angewandte Chemie (International ed. in English), vol. 40, (no. 5), pp. 875-877, March 2, 2001. | Journal Article
2000
Metal-mediated synthesis of medium-sized rings.
Yet, L
Chemical reviews, vol. 100, (no. 8), pp. 2963-3008, August 9, 2000. | Journal Article