Research in the Borchert laboratory explores the regulation of gene expression by noncoding RNAs and G4s. Our main focuses are on microRNAs (miRNAs), microRNA-like sequences excised from other RNAs (e.g., tRNAs and snoRNAs), sRNAs (similarly functioning short noncoding RNAs in prokaryotes), and long noncoding RNAs. Our lab examines the roles noncoding RNAs and G4 structures play during growth and development, infectious disease, how their misregulations contribute to various diseases and oncogenesis, and also how they evolve and contribute to speciation.
Expertise:
- Regulation of gene expression by small RNAs
