118 Publications (Page 1 of 5)
2018
Permeability and calcium signaling in lung endothelium: unpack the box…
Townsley, Mary I
Pulmonary Circulation, vol. 8, (no. 1), Jan 2018. | Journal Article
2016
Endothelial hyperpermeability in severe pulmonary arterial hypertension: role of store-operated calcium entry
Zhou, Chun⋅Townsley, Mary I⋅Alexeyev, Mikhail⋅Voelkel, Norbert F and Stevens, Troy
American Journal of Physiology. Lung Cellular and Molecular Physiology, vol. 311, (no. 3), pp. L560-L569, Sep 1, 2016. | Journal Article
 
Endothelial SK3 channel-associated Ca2+ microdomains modulate blood pressure
Yap, Fui C⋅Yap, Fui C⋅Weber, David S⋅Weber, David S⋅Taylor, Mark S⋅Taylor, Mark S⋅Townsley, Mary I⋅Townsley, Mary I⋅Comer, Brian S⋅Comer, Brian S⋅Maylie, James⋅Maylie, James⋅Adelman, John P⋅Adelman, John P⋅Lin, Mike T and Lin, Mike T
American Journal of Physiology. Heart and Circulatory Physiology, vol. 310, (no. 9), pp. H1151-H1163, May 1, 2016. | Journal Article
 
In Memoriam: Aubrey E. Taylor (1933-2015)
Granger, D N and Townsley, Mary I
The Physiologist, vol. 59, (no. 2), pp. 117-118, Mar 2016. | Journal Article
2015
Functional coupling of TRPV4, IK, and SK channels contributes to Ca2+-dependent endothelial injury in mouse lung
Lin, M.T.⋅Jian, M.Y.⋅Taylor, M.S.⋅Cioffi, D.L.⋅Liedtke, W. and Townsley, M.I.
Pulmonary Circulation, vol. 5, pp. 279-290, 2015. | Journal Article
 
Lung Endothelium
Townsley, Mary I and Stevens, T.
San Francisco: Morgan & Claypool Publishers. 2015. Colloquium series on integrated physiology. | Book
 
The effects of mitochondrial complex I blockade on ATP and permeability in rat pulmonary microvascular endothelial cells in culture (PMVEC) are overcome by coenzyme Q1 (CoQ1)
Bongard, Robert D⋅Townsley, Mary I and Merker, Marilyn P
Free Radical Biology & Medicine, vol. 79, pp. 69-77, Feb 2015. | Journal Article
 
Potential therapeutic applications for TRPV4 antagonists in lung disease.
Townsley, M.I. and Parker, J.C.
In TRP channels as therapeutic targets: from basic science to clinical use. (pp. 221-238). Elsevier. 2015. | Book Chapter
2014
Role of MMP2 and MMP9 in TRPV4-induced lung injury
Villalta, Patricia C⋅Rocic, Petra and Townsley, Mary I
American Journal of Physiology. Lung Cellular and Molecular Physiology, vol. 307, (no. 8), pp. L652-L659, Oct 15, 2014. | Journal Article
2013
Depleted energy charge and increased pulmonary endothelial permeability induced by mitochondrial complex I inhibition are mitigated by coenzyme Q1 in the isolated perfused rat lung.
Bongard, Robert D⋅Yan, Ke⋅Hoffmann, Raymond G⋅Audi, Said H⋅Zhang, Xiao⋅Lindemer, Brian J⋅Townsley, Mary I and Merker, Marilyn P
Free radical biology & medicine, vol. 65, pp. 1455-63, 2013/Dec. | Journal Article
 
Transient receptor potential channels and regulation of lung endothelial permeability
Villalta, P.C. and Townsley, M.I.
Pulmonary Circulation, vol. 3, (no. 4), pp. 802-815, 2013. | Journal Article
 
TRPV4 calcium entry and surface expression attenuated by inhibition of myosin light chain kinase in rat pulmonary microvascular endothelial cells.
Parker, James C⋅Hashizumi, Masahiro⋅Kelly, Sarah V⋅Francis, Michael⋅Mouner, Marc⋅Meyer, Angela L⋅Townsley, Mary I⋅Wu, Songwei⋅Cioffi, Donna L and Taylor, Mark S
Physiological reports, vol. 1, (no. 5), pp. e00121, 2013/Oct. | Journal Article
2012
An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure
Thorneloe, Kevin S⋅Cheung, Mui⋅Bao, Weike⋅Alsaid, Hasan⋅Lenhard, Stephen⋅Jian, Ming-Yuan⋅Costell, Melissa⋅Maniscalco-Hauk, Kristeen⋅Krawiec, John A⋅Olzinski, Alan⋅Gordon, Earl⋅Lozinskaya, Irina⋅Elefante, Lou⋅Qin, Pu⋅Matasic, Daniel S⋅James, Chris⋅Tunstead, James⋅Donovan, Brian⋅Kallal, Lorena⋅Waszkiewicz, Anna⋅Vaidya, Kalindi⋅Davenport, Elizabeth A⋅Larkin, Jonathan⋅Burgert, Mark⋅Casillas, Linda N⋅Marquis, Robert W⋅Ye, Guosen⋅Eidam, Hilary S⋅Goodman, Krista B⋅Toomey, John R⋅Roethke, Theresa J⋅Jucker, Beat M⋅Schnackenberg, Christine G⋅Townsley, Mary I⋅Lepore, John J and Willette, Robert N
Science Translational Medicine, vol. 4, (no. 159), pp. 159ra148, Nov 7, 2012. | Journal Article
 
Structure and composition of pulmonary arteries, capillaries, and veins.
Townsley, Mary I
Comprehensive Physiology, vol. 2, (no. 1), pp. 675-709, 2012/Jan. | Journal Article
2011
Control of TRPV4 and its effect on the lung
Parker, J.C. and Townsley, M.I.
In Mechanosensitivity in cells and tissues. (pp. 239-254). Springer. 2011. | Book Chapter
2010
Impact of epoxyeicosatrienoic acids in lung ischemia-reperfusion injury.
Townsley, Mary I⋅Morisseau, Christophe⋅Hammock, Bruce and King, Judy A
Microcirculation (New York, N.Y. : 1994), vol. 17, (no. 2), pp. 137-46, 2010/Feb. | Journal Article
 
TRPV4 channels augment macrophage activation and ventilator-induced lung injury
Hamanaka, Kazutoshi⋅Jian, Ming-Yuan⋅Townsley, Mary I⋅King, Judy A⋅Liedtke, Wolfgang B⋅Weber, David S⋅Eyal, Fabien G⋅Clapp, Mary M and Parker, James C
American Journal of Physiology, vol. 299, (no. 3), Sep 2010. | Journal Article
 
α1G T-type calcium channel selectively regulates P-selectin surface expression in pulmonary capillary endothelium
Chun Zhou⋅Hairu Chen⋅Judy A. King⋅Hassan Sellak⋅Wolfgang M. Kuebler⋅Jun Yin⋅Mary I. Townsley⋅Hee-Sup Shin and Songwei Wu
American Journal of Physiology - Lung Cellular and Molecular Physiology, vol. 299, (no. 1), pp. 86-97, Jul 1, 2010. | Journal Article
2009
Ca2+ entry via α1G and TRPV4 channels differentially regulates surface expression of P-selectin and barrier integrity in pulmonary capillary endothelium
Songwei Wu⋅Ming-Yuan Jian⋅Yan-Chun Xu⋅Chun Zhou⋅Abu-Bakr Al-Mehdi⋅Wolfgang Liedtke⋅Hee-Sup Shin and Mary I. Townsley
American Journal of Physiology - Lung Cellular and Molecular Physiology, vol. 297, (no. 4), pp. 650-657, Oct 1, 2009. | Journal Article
 
Pulmonary edema
Moore, T.M. and Townsley, M.I.
In Encyclopedia of molecular mechanisms of disease. (pp. 1764-1766). Springer. 2009. | Book Chapter
2008
High Vascular Pressure-Induced Lung Injury Requires P450 Epoxygenase-Dependent Activation of TRPV4
Jian, Ming-Yuan⋅King, Judy A⋅Al Mehdi, Abu Bakr⋅Liedtke, Wolfgang B and Townsley, Mary I
American Journal of Respiratory Cell and Molecular Biology, vol. 38, (no. 4), pp. 386-92, Apr 2008. | Journal Article
 
Physiological determinants of the pulmonary filtration coefficient
Parker, James C and Townsley, Mary I
American Journal of Physiology, vol. 295, (no. 2), Aug 2008. | Journal Article
2007
TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs
Hamanaka, Kazutoshi⋅Jian, Ming-Yuan⋅Weber, David S⋅Alvarez, Diego F⋅Townsley, Mary I⋅Al Mehdi, Abu Bakr⋅King, Judy A⋅Liedtke, Wolfgang B and Parker, James C
American Journal of Physiology: Lung Cellular and Molecular Physiology, vol. 293, (no. 4), pp. L923-L932, 2007. | Journal Article
2006
Ca2+ channels and pulmonary endothelial permeability: insights from study of intact lung and chronic pulmonary hypertension.
Townsley, Mary I⋅King, Judy A and Alvarez, Diego F
Microcirculation (New York, N.Y. : 1994), vol. 13, (no. 8), pp. 725-39, 2006/Dec. | Journal Article
 
Special topics issue of microcirculation: ion channels and pulmonary vascular function.
Townsley, Mary I
Microcirculation (New York, N.Y. : 1994), vol. 13, (no. 8), pp. 611-3, 2006/Dec. | Journal Article