49 Publications (Page 1 of 2)
2013
Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: role of ogg1.
Yuzefovych, Larysa VYuzefovych, Larysa VSchuler, A MSchuler, A MChen, JemimahChen, JemimahAlvarez, Diego FAlvarez, Diego FEide, LarsEide, LarsLeDoux, Susan PLeDoux, Susan PWilson, Glenn LWilson, Glenn LRachek, Lyudmila I and Rachek, Lyudmila I
Endocrinology, vol. 154, (no. 8), pp. 2640-9, 2013/Aug. | Journal Article
 
Mitochondrial DNA Damage via Augmented Oxidative Stress Regulates Endoplasmic Reticulum Stress and Autophagy: Crosstalk, Links and Signaling.
Yuzefovych, Larysa VYuzefovych, Larysa VLeDoux, Susan PLeDoux, Susan PWilson, Glenn LWilson, Glenn LRachek, Lyudmila I and Rachek, Lyudmila I
PloS one, vol. 8, (no. 12), pp. e83349, 2013. | Journal Article
2010
The approaches for manipulating mitochondrial proteome.
Shokolenko, Inna NAlexeyev, Mikhail FLeDoux, Susan P and Wilson, Glenn L
Environmental and molecular mutagenesis, vol. 51, (no. 5), pp. 451-61, 2010/Jun. | Journal Article
 
University of South Alabama College of Medicine.
LeDoux, Susan P and Guest, Joyce M
Academic medicine : journal of the Association of American Medical Colleges, vol. 85, (no. 9 Suppl), pp. S74-7, 2010/Sep. | Journal Article
2009
Chapter 15: Targeting Repair Proteins to the Mitochondria of Mammalian Cells Through Stable Transfection, Transient Transfection, Viral Transduction, and TAT-Mediated Protein Transduction
Koczor, CASnyder, JWShokolenko, INDobson, Allison WWilson, Glenn L and LeDoux, Susan P
Methods in Molecular Biology, vol. 554, pp. 233-249, 2009. | Journal Article
 
Mitochondrial DNA Damage Initiates a Cell Cycle Arrest by a Chk2-associated Mechanism in Mammalian Cells
Koczor, Christopher AShokolenko, Inna NBoyd, Amy KBalk, Shawn PWilson, Glenn L and LeDoux, Susan P
Journal of Biological Chemistry, vol. 284, (no. 52), pp. 36191-36201, 2009. | Journal Article
 
Targeting repair proteins to the mitochondria of mammalian cells through stable transfection, transient transfection, viral transduction, and TAT-mediated protein transduction.
Koczor, Christopher ASnyder, Janet WShokolenko, Inna NDobson, Allison WWilson, Glenn L and LeDoux, Susan P
Methods in molecular biology (Clifton, N.J.), vol. 554, pp. 233-49, 2009. | Journal Article
 
Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes.
Rachek, Lyudmila IYuzefovych, Larysa VLeDoux, Susan PJulie, Neil L and Wilson, Glenn L
Toxicology and applied pharmacology, vol. 240, (no. 3), pp. 348-54, 2009/Nov/1. | Journal Article
2008
Mitochondrial DNA repair in aging and disease
Druzhyna, Nadiya MWilson, Glenn L and LeDoux, Susan P
Mechanisms of Ageing and Development, vol. 129, (no. 7-8), pp. 383-390, 2008. | Journal Article
2007
Altering DNA base excision repair: Use of nuclear and mitochondrial-targeted N-methylpurine DNA glycosylase to sensitize astroglia to chemotherapeutic agents
Harrison, Jason FRinne, Mikael LKelley, Mark RDruzhyna, Nadiya MWilson, Glenn LLeDoux, Susan P and Ledoux, Susan P
Glia, vol. 55, (no. 14), pp. 1416-1425, 2007. | Journal Article
 
Mitochondrial DNA repair: a critical player in the response of cells of the CNS to genotoxic insults.
LeDoux, Susan PDruzhyna, N MHollensworth, S BHarrison, J F and Wilson, Glenn L
Neuroscience, vol. 145, (no. 4), pp. 1249-59, 2007/Apr/14. | Journal Article
 
Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress
Ho, ReneeRachek, Lyudmila IXu, YiKelley, Mark RLeDoux, Susan P and Wilson, Glenn L
Journal of Neurochemistry, vol. 102, (no. 1), pp. 13-24, Jul 2007. | Journal Article
 
Yeast apurinicapyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress
Ho, ReneeRachek, Lyudmila IXu, YiKelley, Mark RLeDoux, Susan P and Wilson, Glenn L
Journal of Neurochemistry, vol. 102, (no. 1), pp. 13-24, 2007. | Journal Article
2006
Protection of INS-1 Cells From Free Fatty Acid-Induced Apoptosis by Targeting hOGG1 to Mitochondria
Rachek, Lyudmila IThornley, Nancy PGrishko, Valentina ILeDoux, Susan P and Wilson, Glenn L
Diabetes, vol. 55, (no. 4), pp. 1022-8, Apr 2006. | Journal Article
 
Role of nitric oxide-induced mtDNA damage in mitochondrial dysfunction and apoptosis
Rachek, Lyudmila IGrishko, Valentina ILeDoux, Susan P and Wilson, Glenn L
Free Radical Biology and Medicine, vol. 40, (no. 5), pp. 754-762, 2006. | Journal Article
2005
Contribution of Mitochondrial DNA Repair to Cell Resistance from Oxidative Stress
Grishko, Valentina IRachek, Lyudmila ISpitz, Douglas RWilson, Glenn L and LeDoux, Susan P
Journal of Biological Chemistry, vol. 280, (no. 10), pp. 8901-8905, 2005. | Journal Article
 
Cytokines Induce Nitric Oxide-mediated mtDNA Damage and Apoptosis in Oligodendrocytes: Protective Role Of Targeting 8-Oxoguanine Glycosylase To Mitochondria
Druzhyna, Nadiya MMusiyenko, Sergyi IWilson, Glenn L and LeDoux, Susan P
Journal of biological chemistry., vol. 280, (no. 22), pp. 21673-21679, 2005. | Journal Article
 
Free-Fatty Acid-Induced mtDNA Damage in Rat L6 Skeletal Muscle Cells
Rachek, Lyudmila IGrishko, Valentina ILeDoux, Susan P and Wilson, Glenn L
Diabetes, vol. 54, pp. A379-A380, Jun 2005. | Journal Article
 
Involvement of mtDNA damage in free fatty acid-induced apoptosis
Grishko, ValentinaRachek, LyudmilaMusiyenko, SergiyLeDoux, Susan P and Wilson, Glenn L
Free Radical Biology and Medicine, vol. 38, (no. 6), pp. 755-762, 2005. | Journal Article
 
Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells
Ruchko, Mykhaylo VGorodnya, OlenaLeDoux, Susan PAlexeyev, Mikhail F and al, et
American Journal of Physiology, vol. 32, (no. 3), pp. L530-L535, Mar 2005. | Journal Article
 
Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells.
Ruchko, Mykhaylo VGorodnya, OlenaLeDoux, Susan PAlexeyev, Mikhail FAl Mehdi, Abu Bakr and Gillespie, Mark
American journal of physiology. Lung cellular and molecular physiology, vol. 288, (no. 3), pp. L530-5, 2005/Mar. | Journal Article
 
Oxidative stress-induced apoptosis in neurons correlates with mitochondrial DNA base excision repair pathway imbalance
Harrison, Jason FHollensworth, Scott BSpitz, Douglas RCopeland, William CWilson, Glenn L and LeDoux, Susan P
Nucleic Acids Research, vol. 33, (no. 14), pp. 4660-4671, 2005. | Journal Article
 
Protection Against Free Fatty Acid-Induced Apoptosis in [beta]-Cells by Targeting a Recombinant DNA Repair Enzyme to Mitochondria
Rachek, Lyudmila IGrishko, Valentina ILeDoux, Susan P and Wilson, Glenn L
Diabetes, vol. 54, pp. A78, Jun 2005. | Journal Article
 
TAT-mediated protein transduction and targeted delivery of fusion proteins into mitochondria of breast cancer cells.
Shokolenko, Inna NAlexeyev, Mikhail FLeDoux, Susan P and Wilson, Glenn L
DNA repair, vol. 4, (no. 4), pp. 511-8, 2005/Apr/4. | Journal Article
2004
Endonuclease III and endonuclease VIII conditionally targeted into mitochondria enhance mitochondrial DNA repair and cell survival following oxidative stress
Rachek, Lyudmila IGrishko, Valentina IAlexeyev, Mikhail FPastukh, Viktoriya VLeDoux, Susan P and Wilson, Glenn L
Nucleic Acids Research, vol. 32, (no. 10), pp. 3240-7, May 15, 2004. | Journal Article