49 Publications (Page 1 of 2)
2013
Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: role of ogg1.
Yuzefovych, Larysa V⋅Schuler, A M⋅Chen, Jemimah⋅Alvarez, Diego F⋅Eide, Lars⋅LeDoux, Susan P⋅Wilson, Glenn L and Rachek, Lyudmila I
Endocrinology, vol. 154, (no. 8), pp. 2640-9, 2013/Aug. | Journal Article
 
Mitochondrial DNA Damage via Augmented Oxidative Stress Regulates Endoplasmic Reticulum Stress and Autophagy: Crosstalk, Links and Signaling.
Yuzefovych, Larysa V⋅Yuzefovych, Larysa V⋅LeDoux, Susan P⋅LeDoux, Susan P⋅Wilson, Glenn L⋅Wilson, Glenn L⋅Rachek, Lyudmila I and Rachek, Lyudmila I
PloS one, vol. 8, (no. 12), pp. e83349, 2013. | Journal Article
2010
The approaches for manipulating mitochondrial proteome.
Shokolenko, Inna N⋅Alexeyev, Mikhail F⋅LeDoux, Susan P and Wilson, Glenn L
Environmental and molecular mutagenesis, vol. 51, (no. 5), pp. 451-61, 2010/Jun. | Journal Article
 
University of South Alabama College of Medicine.
LeDoux, Susan P and Guest, Joyce M
Academic medicine : journal of the Association of American Medical Colleges, vol. 85, (no. 9 Suppl), pp. S74-7, 2010/Sep. | Journal Article
2009
Chapter 15: Targeting Repair Proteins to the Mitochondria of Mammalian Cells Through Stable Transfection, Transient Transfection, Viral Transduction, and TAT-Mediated Protein Transduction
Koczor, CA⋅Snyder, JW⋅Shokolenko, IN⋅Dobson, Allison W⋅Wilson, Glenn L and LeDoux, Susan P
Methods in Molecular Biology, vol. 554, pp. 233-249, 2009. | Journal Article
 
Mitochondrial DNA Damage Initiates a Cell Cycle Arrest by a Chk2-associated Mechanism in Mammalian Cells
Koczor, Christopher A⋅Shokolenko, Inna N⋅Boyd, Amy K⋅Balk, Shawn P⋅Wilson, Glenn L and LeDoux, Susan P
Journal of Biological Chemistry, vol. 284, (no. 52), pp. 36191-36201, 2009. | Journal Article
 
Targeting repair proteins to the mitochondria of mammalian cells through stable transfection, transient transfection, viral transduction, and TAT-mediated protein transduction.
Koczor, Christopher A⋅Snyder, Janet W⋅Shokolenko, Inna N⋅Dobson, Allison W⋅Wilson, Glenn L and LeDoux, Susan P
Methods in molecular biology (Clifton, N.J.), vol. 554, pp. 233-49, 2009. | Journal Article
 
Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes.
Rachek, Lyudmila I⋅Yuzefovych, Larysa V⋅LeDoux, Susan P⋅Julie, Neil L and Wilson, Glenn L
Toxicology and applied pharmacology, vol. 240, (no. 3), pp. 348-54, 2009/Nov/1. | Journal Article
2008
Mitochondrial DNA repair in aging and disease
Druzhyna, Nadiya M⋅Wilson, Glenn L and LeDoux, Susan P
Mechanisms of Ageing and Development, vol. 129, (no. 7-8), pp. 383-390, 2008. | Journal Article
2007
Altering DNA base excision repair: Use of nuclear and mitochondrial-targeted N-methylpurine DNA glycosylase to sensitize astroglia to chemotherapeutic agents
Harrison, Jason F⋅Rinne, Mikael L⋅Kelley, Mark R⋅Druzhyna, Nadiya M⋅Wilson, Glenn L⋅LeDoux, Susan P and Ledoux, Susan P
Glia, vol. 55, (no. 14), pp. 1416-1425, 2007. | Journal Article
 
Mitochondrial DNA repair: a critical player in the response of cells of the CNS to genotoxic insults.
LeDoux, Susan P⋅Druzhyna, N M⋅Hollensworth, S B⋅Harrison, J F and Wilson, Glenn L
Neuroscience, vol. 145, (no. 4), pp. 1249-59, 2007/Apr/14. | Journal Article
 
Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress
Ho, Renee⋅Rachek, Lyudmila I⋅Xu, Yi⋅Kelley, Mark R⋅LeDoux, Susan P and Wilson, Glenn L
Journal of Neurochemistry, vol. 102, (no. 1), pp. 13-24, Jul 2007. | Journal Article
 
Yeast apurinicapyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress
Ho, Renee⋅Rachek, Lyudmila I⋅Xu, Yi⋅Kelley, Mark R⋅LeDoux, Susan P and Wilson, Glenn L
Journal of Neurochemistry, vol. 102, (no. 1), pp. 13-24, 2007. | Journal Article
2006
Protection of INS-1 Cells From Free Fatty Acid-Induced Apoptosis by Targeting hOGG1 to Mitochondria
Rachek, Lyudmila I⋅Thornley, Nancy P⋅Grishko, Valentina I⋅LeDoux, Susan P and Wilson, Glenn L
Diabetes, vol. 55, (no. 4), pp. 1022-8, Apr 2006. | Journal Article
 
Role of nitric oxide-induced mtDNA damage in mitochondrial dysfunction and apoptosis
Rachek, Lyudmila I⋅Grishko, Valentina I⋅LeDoux, Susan P and Wilson, Glenn L
Free Radical Biology and Medicine, vol. 40, (no. 5), pp. 754-762, 2006. | Journal Article
2005
Contribution of Mitochondrial DNA Repair to Cell Resistance from Oxidative Stress
Grishko, Valentina I⋅Rachek, Lyudmila I⋅Spitz, Douglas R⋅Wilson, Glenn L and LeDoux, Susan P
Journal of Biological Chemistry, vol. 280, (no. 10), pp. 8901-8905, 2005. | Journal Article
 
Cytokines Induce Nitric Oxide-mediated mtDNA Damage and Apoptosis in Oligodendrocytes: Protective Role Of Targeting 8-Oxoguanine Glycosylase To Mitochondria
Druzhyna, Nadiya M⋅Musiyenko, Sergyi I⋅Wilson, Glenn L and LeDoux, Susan P
Journal of biological chemistry., vol. 280, (no. 22), pp. 21673-21679, 2005. | Journal Article
 
Free-Fatty Acid-Induced mtDNA Damage in Rat L6 Skeletal Muscle Cells
Rachek, Lyudmila I⋅Grishko, Valentina I⋅LeDoux, Susan P and Wilson, Glenn L
Diabetes, vol. 54, pp. A379-A380, Jun 2005. | Journal Article
 
Involvement of mtDNA damage in free fatty acid-induced apoptosis
Grishko, Valentina⋅Rachek, Lyudmila⋅Musiyenko, Sergiy⋅LeDoux, Susan P and Wilson, Glenn L
Free Radical Biology and Medicine, vol. 38, (no. 6), pp. 755-762, 2005. | Journal Article
 
Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells
Ruchko, Mykhaylo V⋅Gorodnya, Olena⋅LeDoux, Susan P⋅Alexeyev, Mikhail F and al, et
American Journal of Physiology, vol. 32, (no. 3), pp. L530-L535, Mar 2005. | Journal Article
 
Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells.
Ruchko, Mykhaylo V⋅Gorodnya, Olena⋅LeDoux, Susan P⋅Alexeyev, Mikhail F⋅Al Mehdi, Abu Bakr and Gillespie, Mark
American journal of physiology. Lung cellular and molecular physiology, vol. 288, (no. 3), pp. L530-5, 2005/Mar. | Journal Article
 
Oxidative stress-induced apoptosis in neurons correlates with mitochondrial DNA base excision repair pathway imbalance
Harrison, Jason F⋅Hollensworth, Scott B⋅Spitz, Douglas R⋅Copeland, William C⋅Wilson, Glenn L and LeDoux, Susan P
Nucleic Acids Research, vol. 33, (no. 14), pp. 4660-4671, 2005. | Journal Article
 
Protection Against Free Fatty Acid-Induced Apoptosis in [beta]-Cells by Targeting a Recombinant DNA Repair Enzyme to Mitochondria
Rachek, Lyudmila I⋅Grishko, Valentina I⋅LeDoux, Susan P and Wilson, Glenn L
Diabetes, vol. 54, pp. A78, Jun 2005. | Journal Article
 
TAT-mediated protein transduction and targeted delivery of fusion proteins into mitochondria of breast cancer cells.
Shokolenko, Inna N⋅Alexeyev, Mikhail F⋅LeDoux, Susan P and Wilson, Glenn L
DNA repair, vol. 4, (no. 4), pp. 511-8, 2005/Apr/4. | Journal Article
2004
Endonuclease III and endonuclease VIII conditionally targeted into mitochondria enhance mitochondrial DNA repair and cell survival following oxidative stress
Rachek, Lyudmila I⋅Grishko, Valentina I⋅Alexeyev, Mikhail F⋅Pastukh, Viktoriya V⋅LeDoux, Susan P and Wilson, Glenn L
Nucleic Acids Research, vol. 32, (no. 10), pp. 3240-7, May 15, 2004. | Journal Article