28 Publications (Page 1 of 2)
2018
Spectral imaging of FRET-based sensors reveals sustained cAMP gradients in three spatial dimensions.
Annamdevula, Naga S⋅Sweat, Rachel⋅Griswold, John R⋅Trinh, Kenny⋅Hoffman, Chase⋅West, Savannah⋅Deal, Joshua⋅Britain, Andrea L⋅Jalink, Kees⋅Rich, Thomas C and Leavesley, Silas J
Cytometry. Part A : the journal of the International Society for Analytical Cytology, September 3, 2018. | Journal Article
2014
Excitation-scanning hyperspectral imaging microscope.
Favreau, Peter F⋅Hernandez, Clarissa⋅Heaster, Tiffany⋅Alvarez, Diego F⋅Rich, Thomas C⋅Prabhat, Prashant and Leavesley, Silas J
Journal of biomedical optics, vol. 19, (no. 4), pp. 46010, 2014/Apr/1. | Journal Article
2013
An approach for characterizing and comparing hyperspectral microscopy systems.
Annamdevula, Naga S⋅Sweat, Brenner⋅Favreau, Peter⋅Lindsey, Ashley S⋅Alvarez, Diego F⋅Rich, Thomas C and Leavesley, Silas J
Sensors (Basel, Switzerland), vol. 13, (no. 7), pp. 9267-93, 2013. | Journal Article
 
Hyperspectral imaging of FRET-based cGMP probes.
Rich, Thomas C⋅Britain, Andrea L⋅Stedman, Tiffany and Leavesley, Silas J
Methods in molecular biology (Clifton, N.J.), vol. 1020, pp. 73-88, 2013. | Journal Article
2012
Assessment of cellular mechanisms contributing to cAMP compartmentalization in pulmonary microvascular endothelial cells
Feinstein, Wei P⋅Zhu, Bing⋅Leavesley, Silas J⋅Sayner, Sarah L and Rich, Thomas C
American Journal of Physiology, vol. 302, (no. 6), Mar 2012. | Journal Article
 
Calcineurin regulates homologous desensitization of natriuretic peptide receptor-A and inhibits ANP-induced testosterone production in MA-10 cells.
Henesy, Michelle B⋅Britain, Andrea L⋅Zhu, Bing⋅Amable, Lauren⋅Honkanen, Richard E⋅Corbin, Jackie D⋅Francis, Sharron H and Rich, Thomas C
PloS one, vol. 7, (no. 8), pp. e41711, 2012. | Journal Article
 
Hyperspectral imaging microscopy for identification and quantitative analysis of fluorescently-labeled cells in highly autofluorescent tissue.
Leavesley, Silas J⋅Annamdevula, Naga⋅Boni, John⋅Stocker, Samantha⋅Grant, Kristin⋅Troyanovsky, Boris⋅Rich, Thomas C and Alvarez, Diego F
Journal of biophotonics, vol. 5, (no. 1), pp. 67-84, 2012/Jan. | Journal Article
2011
Inactivation of multidrug resistance proteins disrupts both cellular extrusion and intracellular degradation of cAMP.
Xie, Moses⋅Rich, Thomas C⋅Scheitrum, Colleen⋅Conti, Marco and Richter, Wito
Molecular pharmacology, vol. 80, (no. 2), pp. 281-93, 2011/Aug. | Journal Article
 
PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblasts.
Blackman, Brigitte E⋅Horner, Kathleen⋅Heidmann, Julia⋅Wang, Dan⋅Richter, Wito⋅Rich, Thomas C and Conti, Marco
The Journal of biological chemistry, vol. 286, (no. 14), pp. 12590-601, 2011/Apr/8. | Journal Article
2010
Quantitative modeling of GRK-mediated beta2AR regulation.
Vayttaden, Sharat J⋅Vayttaden, Sharat J⋅Friedman, Jacqueline⋅Friedman, Jacqueline⋅Tran, Tuan M⋅Tran, Tuan M⋅Rich, Thomas C⋅Rich, Thomas C⋅Dessauer, Carmen W⋅Dessauer, Carmen W⋅Clark, Richard B and Clark, Richard B
PLoS computational biology, vol. 6, (no. 1), pp. e1000647, 2010/Jan. | Journal Article
2009
Receptor reserve reflects differential intrinsic efficacy associated with opioid diastereomers
Carliss, RDS⋅Keefer, JF⋅Perschke, S.⋅Welch, S.⋅Rich, Thomas C and Weissman, AD
Pharmacology Biochemistry and Behavior, vol. 92, (no. 3), pp. 495-502, 2009. | Journal Article
2008
Roles of GRK and PDE4 activities in the regulation of beta2 adrenergic signaling.
Xin, Wenkuan⋅Tran, Tuan M⋅Richter, Wito⋅Clark, Richard B and Rich, Thomas C
The Journal of general physiology, vol. 131, (no. 4), pp. 349-64, 2008/Apr. | Journal Article
2007
Cellular mechanisms underlying prostaglandin-induced transient cAMP signals near the plasma membrane of HEK-293 cells.
Rich, Thomas C⋅Xin, Wenkuan⋅Mehats, Celine⋅Hassell, Kathryn A⋅Piggott, Leslie A⋅Le, Xuan⋅Karpen, Jeffrey W and Conti, Marco
American journal of physiology. Cell physiology, vol. 292, (no. 1), pp. C319-31, 2007/Jan. | Journal Article
2006
Natriuretic Peptides and Nitric Oxide Stimulate cGMP Synthesis in Different Cellular Compartments
Piggott, Leslie A⋅Hassell, Kathryn A⋅Berkova, Zuzana⋅Morris, Andrew P⋅Silberbach, Michael and Rich, Thomas C
Journal of General Physiology, vol. 128, (no. 1), pp. 3-14, 2006. | Journal Article
2005
High-throughput screening of phosphodiesterase activity in living cells.
Rich, Thomas C and Karpen, Jeffrey W
Methods in molecular biology (Clifton, N.J.), vol. 307, pp. 45-61, 2005. | Journal Article
2004
Functional role of lipid raft microdomains in cyclic nucleotide-gated channel activation.
Brady, J. D.⋅Brady, James D⋅Brady, J.D.⋅Rich, Thomas C⋅Rich, T. C.⋅Rich, T.C.⋅Le, Xuan⋅Le, X.⋅Stafford, K.⋅Stafford, Kimberlee⋅Fowler, C.J.⋅Fowler, Cedar J⋅Lynch, Leatha⋅Lynch, L.⋅Karpen, Jeffrey W⋅Karpen, J.W.⋅Brown, R.L.⋅Brown, R L⋅Martens, Jeff and Martens, J.R.
Molecular pharmacology, vol. 65, (no. 3), pp. 503-11, 2004/Mar. | Journal Article
2003
Probing the roles of protein kinases in g-protein-coupled receptor desensitization.
Clark, Richard B and Rich, Thomas C
Molecular pharmacology, vol. 64, (no. 5), pp. 1015-7, 2003/Nov. | Journal Article
2002
Mutations throughout the S6 region of the hKv1.5 channel alter the stability of the activation gate.
Rich, Thomas C⋅Yeola, Sarita W⋅Tamkun, Michael M and Snyders, Dirk J
American journal of physiology. Cell physiology, vol. 282, (no. 1), pp. C161-71, 2002/Jan. | Journal Article
 
Review Article: Cyclic AMP Sensors in Living Cells: What Signals Can They Actually Measure?
Rich, Thomas C and Karpen, Jeffrey W
Annals of Biomedical Engineering, vol. 30, (no. 8), pp. 1088-1099, 2002. | Journal Article
2001
A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell.
Rich, Thomas C⋅Fagan, K A⋅Tse, T E⋅Schaack, J⋅Cooper, Dermot and Karpen, Jeffrey W
Proceedings of the National Academy of Sciences of the United States of America, vol. 98, (no. 23), pp. 13049-54, 2001/Nov/6. | Journal Article
 
In vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors.
Rich, Thomas C⋅Tse, T E⋅Rohan, J G⋅Schaack, J and Karpen, Jeffrey W
The Journal of general physiology, vol. 118, (no. 1), pp. 63-78, 2001/Jul. | Journal Article
 
The fourth dimension in cellular signaling.
Karpen, Jeffrey W and Rich, Thomas C
Science, vol. 293, (no. 5538), pp. 2204-5, 2001/Sep/21. | Journal Article
2000
Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion.
Rich, Thomas C⋅Fagan, K A⋅Nakata, H⋅Schaack, J⋅Cooper, Dermot and Karpen, Jeffrey W
The Journal of General Physiology, vol. 116, (no. 2), pp. 147-61, 2000/Aug. | Journal Article
1999
Adenovirus-mediated expression of an olfactory cyclic nucleotide-gated channel regulates the endogenous Ca2+-inhibitable adenylyl cyclase in C6-2B glioma cells.
Fagan, K A⋅Rich, Thomas C⋅Tolman, S⋅Schaack, J⋅Karpen, J W and Cooper, D M
The Journal of biological chemistry, vol. 274, (no. 18), pp. 12445-53, 1999/Apr/30. | Journal Article
1998
Evidence for multiple open and inactivated states of the hKv1.5 delayed rectifier.
Rich, Thomas C and Snyders, D J
Biophysical journal, vol. 75, (no. 1), pp. 183-95, 1998/Jul. | Journal Article