Area of Expertise:
- Biomechanics
- Neuromuscular control
- Tissue mechanics
- MRI
- Musculoskeletal injury
- Rehabilitation
- ACL
- Osteoarthritis.
Research Intrests:
- Using a multiscale neuromechanics approach, Dr. Lowe aims to characterize knee osteoarthritis progression and identify the relationship between neuromuscular control, and macro-to-tissue biomechanics.
- Characterize intra-tissue properties (e.g., strain and stiffness) in healthy, advanced OA and longitudinally in an ACL reconstruction cohort to identify key timepoints to target for intervention.
- Establish a routine, clinical workflow to relate gait biomechanics to cartilage strain and stiffness and identify functional macro-scale biomarkers of cartilage degeneration and targets for gait retraining.
- Determine the neuromuscular adaptations and their associations with cartilage intratissue properties and identify neuromuscular targets for retraining.
Currently, his primary focus involves translating macro-to-tissue biomechanics and understanding the direct transfer of mechanical load from human motion to cartilage and related joint tissues.
He is very interested in imaging techniques to predict the progression of osteoarthritis, the clinical translation of new imaging methods to study cartilage health and leveraging these into new multiscale interventions to alleviate long-term impairment and enhance quality of life.
Biomechanics, Neuromuscular Control, MRI
