My laboratory is interested in the genetic regulation of inositol metabolism during growth and development of eukaryotes.
Using unicellular and multicellular model organisms, we will: (1) delineate mechanisms by which inositol biosynthesis is compartmentalized, (2) question the generality and compartmentalization of inositol biosynthesis in animal cells (neurons in particular), and (3) eventually ask if there are disease states associated with the decompartmentalization/deregulation of inositol phosphate biosynthesis.
