Expertise

Areas of Specialty:

  • Iron acquisition by active transport through the cell envelopes of bacteria
  • Immunological approaches to bacterial pathogenesis
  • Biophysical analyses of bacterial membrane transport in living cells

We are researching one such complex of proteins (TonB-dependent iron transport systems) in Gram-negative cells, and another network of cell envelope proteins (sortase-dependent and independent heme/hemoglobin transporters) in Gram-positive cells.

Our research focuses on the importance of iron in pathological or pathogenic conditions.


Research:

  • Biochemistry & Molecular Biophysics – Studies iron deprivation as a means of retarding cancer cell growth and as a therapy to block microbial infections in cancer patients

Expertise: Studies active transport, parthenogenesis and membrane transport in bacteria.

Communities
Biochemistry, Biophysics, Cellular Biochemistry, Molecular Biochemistry, Physics
Degrees
PhD, University of California, Berkeley, Biochemistry, 1982
BS, University of Notre Dame, Biology, 1975