83 Publications (Page 1 of 4)
2024
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation.
Nguyen, Bao VĂ–zden, CanDong, KairongTorres-Ocampo, Ana PDziedzic, NoelleFlaherty, DanielHuang, JianSankura, SakethAbromson, Nikki LynTomchick, Diana RChen, JianhanGarman, Scott C and Stratton, Margaret M
bioRxiv : the preprint server for biology, March 27, 2024. | Journal Article
 
Structural basis for hyperpolarization-dependent opening of human HCN1 channel
Burtscher, VerenaMount, JonathanHuang, JianCowgill, JohnChang, YongchangBickel, KathleenChen, JianhanYuan, Peng and Chanda, Baron
Nature communications, vol. 15, (no. 1), pp. 5216, Jun 18, 2024. | Journal Article
 
Targeting TRP channels: recent advances in structure, ligand binding, and molecular mechanisms
Huang, JianKorsunsky, AronYazdani, Mahdieh and Chen, Jianhan
Frontiers in Molecular Neuroscience, Jan 11, 2024. | Journal Article
2023
Hydrophobic gating in bundle-crossing ion channels: a case study of TRPV4
Huang, Jian and Chen, Jianhan
Communications Biology, vol. 6, (no. 1), pp. 1094, 2023. | Journal Article
 
Incorporating physics to overcome data scarcity in predictive modeling of protein function: a case study of BK channels.
Nordquist, ErikZhang, GuohuiBarethiya, ShrishtiJi, NathanWhite, Kelli MHan, LuJia, ZhiguangShi, JingyiCui, Jianmin and Chen, Jianhan
bioRxiv : the preprint server for biology, June 26, 2023. | Journal Article
 
Incorporating physics to overcome data scarcity in predictive modeling of protein function: A case study of BK channels.
Nordquist, ErikZhang, GuohuiBarethiya, ShrishtiJi, NathanWhite, Kelli MHan, LuJia, ZhiguangShi, JingyiCui, Jianmin and Chen, Jianhan
PLoS computational biology, vol. 19, (no. 9), pp. e1011460, September 2023. | Journal Article
 
Machine Learning Generation of Dynamic Protein Conformational Ensembles
Li-E, ZhengLi-E, ZhengBarethiya, ShrishtiBarethiya, ShrishtiNordquist, ErikChen, Jianhan and Chen, Jianhan
Molecules, vol. 28, (no. 10), 2023. | Journal Article
 
Re-Balancing Replica Exchange with Solute Tempering for Sampling Dynamic Protein Conformations.
Zhang, YumengLiu, Xiaorong and Chen, Jianhan
Journal of chemical theory and computation, February 15, 2023. | Journal Article
 
Targeting TRP channels: recent advances in structure, ligand binding, and molecular mechanisms.
Huang, JianKorsunsky, AronYazdani, Mahdieh and Chen, Jianhan
Frontiers in molecular neuroscience, vol. 16, pp. 1334370, 2023. | Journal Article
 
Toward Accurate Simulation of Coupling between Protein Secondary Structure and Phase Separation.
Zhang, YumengLi, ShanlongGong, Xiping and Chen, Jianhan
Journal of the American Chemical Society, December 19, 2023. | Journal Article
2022
Computationally-Aided Modeling of Hsp70-Client Interactions: Past, Present, and Future.
Nordquist, Erik BClerico, Eugenia MChen, Jianhan and Gierasch, Lila M
The journal of physical chemistry. B, August 30, 2022. | Journal Article
 
Intrinsically disordered N-terminal domain (NTD) of p53 interacts with mitochondrial PTP regulator Cyclophilin D.
Zhao, JingLiu, XinyueBlayney, AlanZhang, YumengGandy, LaurenOlivia Mirsky, PaigeSmith, NathanZhang, FumingLinhardt, Robert JChen, JianhanBaines, ChristopherLoh, Stewart N and Wang, Chunyu
Journal of molecular biology, pp. 167552, March 24, 2022. | Journal Article
 
Toward Accurate Coarse-Grained Simulations of Disordered Proteins and Their Dynamic Interactions.
Zhang, YumengLiu, Xiaorong and Chen, Jianhan
Journal of chemical information and modeling, vol. 62, (no. 18), pp. 4523-4536, September 26, 2022. | Journal Article
 
Using Metadynamics To Explore the Free Energy of Dewetting in Biologically Relevant Nanopores.
Nordquist, Erik BSchultz, Samantha A and Chen, Jianhan
The journal of physical chemistry. B, August 23, 2022. | Journal Article
2021
Advanced Sampling Methods for Multiscale Simulation of Disordered Proteins and Dynamic Interactions
Gong, XipingGong, XipingZhang, YumengZhang, YumengChen, Jianhan and Chen, Jianhan
Biomolecules, vol. 11, (no. 10), 2021. | Journal Article
 
Cancer-Associated Mutations Perturb the Disordered Ensemble and Interactions of the Intrinsically Disordered p53 Transactivation Domain.
Schrag, Lynn GSchrag, Lynn GLiu, XiaorongLiu, XiaorongThevarajan, IndhujahThevarajan, IndhujahPrakash, OmPrakash, OmZolkiewski, MichalZolkiewski, MichalChen, Jianhan and Chen, Jianhan
Journal of molecular biology, pp. 167048, May 10, 2021. | Journal Article
 
EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction
Zhao, JingZhao, JingZhao, JingZhao, JingBlayney, AlanBlayney, AlanBlayney, AlanBlayney, AlanLiu, XiaorongLiu, XiaorongLiu, XiaorongLiu, XiaorongGandy, LaurenGandy, LaurenGandy, LaurenGandy, LaurenJin, WeihuaJin, WeihuaJin, WeihuaJin, WeihuaLufeng, YanLufeng, YanLufeng, YanLufeng, YanCanning, Ashley JCanning, Ashley JCanning, Ashley JCanning, Ashley JConnelly, MichaelConnelly, MichaelConnelly, MichaelConnelly, MichaelYang, ChaoYang, ChaoYang, ChaoYang, ChaoCosgrove, Michael SCosgrove, Michael SCosgrove, Michael SCosgrove, Michael SSolmaz, Sozanne RSolmaz, Sozanne RSolmaz, Sozanne RSolmaz, Sozanne RBan, DavidBan, DavidBan, DavidBan, DavidChen, JianhanChen, JianhanChen, JianhanChen, JianhanLoh, Stewart NLoh, Stewart NLoh, Stewart NLoh, Stewart NWang, ChunyuWang, ChunyuWang, Chunyu and Wang, Chunyu
Nature Communications, vol. 12, (no. 1), 2021. | Journal Article
 
Physics-based modeling provides predictive understanding of selectively promiscuous substrate binding by Hsp70 chaperones.
Nordquist, Erik BEnglish, Charles AClerico, Eugenia MSherman, WoodyGierasch, Lila MGierasch, Lila M and Chen, Jianhan
PLoS computational biology, vol. 17, (no. 11), pp. e1009567, November 2021. | Journal Article
 
Specific PIP2 binding promotes calcium activation of TMEM16A chloride channels.
Jia, Zhiguang and Chen, Jianhan
Communications biology, vol. 4, (no. 1), pp. 259, February 26, 2021. | Journal Article
2020
Accelerating atomistic simulations of proteins using multiscale enhanced sampling with independent tempering.
Liu, XiaorongGong, Xiping and Chen, Jianhan
Journal of computational chemistry, December 10, 2020. | Journal Article
 
Bioinspired bio-voltage memristors
Liu, XiaomengWard, Joy ELiu, XiaorongYin, BingYe, ZhuoJoshua, Yang JChen, Jianhan and Yao, Jun
Nature Communications, vol. 11, (no. 1), 2020. | Journal Article
 
Bioinspired bio-voltage memristors.
Fu, TiandaLiu, XiaomengGao, HongyanWard, Joy ELiu, XiaorongYin, BingWang, ZhongruiZhuo, YeWalker, David J FJoshua Yang, JChen, JianhanLovley, Derek R and Yao, Jun
Nature communications, vol. 11, (no. 1), pp. 1861, April 20, 2020. | Journal Article
 
Different Anomeric Sugar Bound States of Maltose Binding Protein Resolved by a Cytolysin A Nanopore Tweezer.
Li, XinLee, Kuo HaoShorkey, SpencerChen, Jianhan and Chen, Min
ACS nano, vol. 14, (no. 2), pp. 1727-1737, February 25, 2020. | Journal Article
 
Modulation of p53 Transactivation Domain Conformations by Ligand Binding and Cancer-Associated Mutations.
Liu, Xiaorong and Chen, Jianhan
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, vol. 25, pp. 195-206, 2020. | Journal Article
 
Power generation from ambient humidity using protein nanowires
Liu, XiaomengGao, HongyanWard, Joy ELiu, XiaorongYin, BingFu, TiandaChen, JianhanLovley, Derek R and Yao, Jun
Nature, vol. 578, (no. 7796), pp. 550-554,554A-554B, Feb 27, 2020. | Journal Article