11 Publications
2013
An intact sialoadhesin (Sn/SIGLEC1/CD169) is not required for attachment/internalization of the porcine reproductive and respiratory syndrome virus.
Prather, Randall S⋅Rowland, Raymond R⋅Ewen, Catherine⋅Trible, Benjamin⋅Kerrigan, Maureen⋅Bawa, Bhupinder⋅Teson, Jennifer M⋅Mao, Jiude⋅Lee, Kiho⋅Samuel, Melissa S⋅Whitworth, Kristin M⋅Murphy, Clifton N⋅Egen, Tina and Green, Jonathan A
Journal of virology, vol. 87, (no. 17), pp. 9538-46, 2013/Sep. | Journal Article
 
Granzyme H induces cell death primarily via a Bcl-2-sensitive mitochondrial cell death pathway that does not require direct Bid activation.
Ewen, Catherine⋅Kane, Kevin P and Bleackley, Robert C
Molecular immunology, vol. 54, (no. 3-4), pp. 309-18, 2013/Jul. | Journal Article
2012
A quarter century of granzymes
Ewen, C⋅Kane, K and Bleackley, R
Cell Death and Differentiation, vol. 19, (no. 1), pp. 28-35, Jan 2012. | Journal Article
2011
Programmed death-1 is required for systemic self-tolerance in newly generated T cells during the establishment of immune homeostasis.
Thangavelu, G⋅Parkman, J C⋅Ewen, Catherine⋅Uwiera, R R⋅Baldwin, T A and Anderson, C C
Journal of autoimmunity, vol. 36, (no. 3-4), pp. 301-12, 2011/May. | Journal Article
 
The human cathelicidin, LL-37, induces granzyme-mediated apoptosis in regulatory T cells.
Mader, Jamie S⋅Ewen, Catherine⋅Hancock, Robert E and Bleackley, Robert C
Journal of immunotherapy (Hagerstown, Md. : 1997), vol. 34, (no. 3), pp. 229-35, 2011/Apr. | Journal Article
2009
Granzyme B: Correlates with protection and enhanced CTL response to influenza vaccination in older adults.
Mc Elhaney, Janet E⋅Ewen, Catherine⋅Zhou, Xin⋅Kane, Kevin P⋅Xie, Dongxu⋅Hager, W D⋅Barry, Mary B⋅Kleppinger, Alison⋅Wang, Yazhen and Bleackley, Robert C
Vaccine, vol. 27, (no. 18), pp. 2418-25, 2009/Apr/21. | Journal Article
2006
Evaluating antigen-specific cytotoxic T lymphocyte responses by a novel mouse granzyme B ELISPOT assay
Ewen, Catherine⋅Rong, Jian Hui⋅Kokaji, AI⋅Bleackley, Robert C and Kane, Kevin P
Journal of Immunological Methods, vol. 308, (no. 1-2), pp. 156-166, 2006. | Journal Article
 
T cell responses are better correlates of vaccine protection in the elderly.
Mc Elhaney, Janet E⋅Xie, Dongxu⋅Hager, W D⋅Barry, Mary B⋅Wang, Yazhen⋅Kleppinger, Alison⋅Ewen, Catherine⋅Kane, Kevin P and Bleackley, Robert C
Journal of immunology (Baltimore, Md. : 1950), vol. 176, (no. 10), pp. 6333-9, 2006/May/15. | Journal Article
2005
Impaired Cytolytic Activity in Calreticulin-Deficient CTLs
Sipione, Simonetta⋅Ewen, Catherine⋅Shostak, Irene⋅Michalak, Marek and Bleackley, RChris
Journal of Immunology, vol. 174, (no. 6), pp. 3212-3219, 2005. | Journal Article
2004
Isolation and Characterization of Novel Single-Chain Fv Specific for Human Granzyme B
Rong, Jianhui⋅Xu, Xiaolin⋅Ewen, Catherine⋅Bleackley, Robert C and Kane, Kevin P
Hybridoma and Hybridomics, vol. 23, (no. 4), pp. 219-231, 2004. | Journal Article
2003
A novel cytotoxicity assay to evaluate antigen-specific CTL responses using a colorimetric substrate for Granzyme B
Ewen, Catherine⋅Kane, Kevin P⋅Shostak, I.⋅Griebel, PJ⋅Bertram, EM⋅Watts, Tania H⋅Bleackley, Robert C and Mc Elhaney, Janet E
Journal of Immunological Methods, vol. 276, (no. 1-2), pp. 89-101, 2003. | Journal Article