I am interested in studying protein structure and function using the variety of biophysical techniques including proteomics analysis, structural analysis, and protein-protein interaction analysis. As Associate Director of the Biotechnology Core facility, I have worked with numerous researchers determing protein/peptide sequence employing with proteomics technologies including 2D gels, MALDI-TOF/TOF MS and ESI-MS instruments. For my own research I focus on the regulation of human pyruvate dehydrogenase complex (PDC) by specific kinases and phosphatases. The PDC is responsible for the regulation of energy and metabolite producing TCA cycle in mitochondria.
- Proteomics
- Peptide/protein characterization
- Protein interaction
- Regulation of protein complex
- am interested in studying protein structure and function using the variety of biophysical techniques including proteomics analysis, structural analysis, and protein-protein interaction analysis. As Associate Director of the Biotechnology Core facility, I have worked with numerous researchers determing protein/peptide sequence employing with proteomics technologies including 2D gels, MALDI-TOF/TOF MS and ESI-MS instruments. For my own research I focus on the regulation of human pyruvate dehydrogenase complex (PDC) by specific kinases and phosphatases. The PDC is responsible for the regulation of energy and metabolite producing TCA cycle in mitochondria.
