54 Publications (Page 1 of 3)
2021
Arginine glycosylation enhances methylglyoxal detoxification
El Qaidi, SamirScott, Nichollas EScott, Nichollas EHardwidge, Philip R and Hardwidge, Philip R
Scientific Reports (Nature Publisher Group), vol. 11, (no. 1), 2021. | Journal Article
 
The Role of Innate Immunity in Pulmonary Infections
Zhang, HuihuiHe, FangPan, LiHardwidge, Philip RLi, Nengzhang and Peng, Yuanyi
BioMed Research International, vol. 2021, 2021. | Journal Article
2020
An intra-bacterial activity for a T3SS effector
El Qaidi, SamirScott, Nichollas EScott, Nichollas EScott, Nichollas EHays, Michael PHays, Michael PHays, Michael PGeisbrecht, Brian VGeisbrecht, Brian VGeisbrecht, Brian VWatkins, ShelbyWatkins, ShelbyWatkins, ShelbyHardwidge, Philip RHardwidge, Philip R and Hardwidge, Philip R
Scientific Reports (Nature Publisher Group), vol. 10, (no. 1), 2020. | Journal Article
2018
Isolation and Characterization of N-acyl Homoserine Lactone-Producing Bacteria From Cattle Rumen and Swine Intestines.
Yang, YangZhou, MingxuHardwidge, Philip RCui, Hengmi and Zhu, Guoqiang
Frontiers in cellular and infection microbiology, vol. 8, pp. 155, 2018. | Journal Article
2016
Construction and sequencing of an infectious clone of the goose embryo-adapted Muscovy duck parvovirus vaccine strain FZ91-30
Wang, JianyeWang, JianyeHuang, YuHuang, YuZhou, MingxuZhou, MingxuHardwidge, Philip RHardwidge, Philip RZhu, Guoqiang and Zhu, Guoqiang
Virology Journal, vol. 13, 2016. | Journal Article
2015
More than a locomotive organelle: flagella in Escherichia coli
Zhou, MingxuYang, YangChen, PanlinHu, HuijieHardwidge, Philip R and Zhu, Guoqiang
(pp. 8883-8890). Nov 2015
 
Protective Enterotoxigenic Escherichia coli Antigens in a Murine Intranasal Challenge Model.
Kumar, AmitHays, MikeLim, FrancisFoster, Leonard JZhou, MingxuZhu, GuoqiangMiesner, Tracy and Hardwidge, Philip R
PLoS neglected tropical diseases, vol. 9, (no. 8), pp. e0003924, 2015. | Journal Article
2014
'Drugs from bugs': bacterial effector proteins as promising biological (immune-) therapeutics.
Rüter, Christian and Hardwidge, Philip R
FEMS microbiology letters, vol. 351, (no. 2), pp. 126-132, February 2014. | Journal Article
 
Enterotoxigenic Escherichia coli infection induces intestinal epithelial cell autophagy.
Tang, YulongLi, FengnaTan, BieLiu, GangKong, XiangfengHardwidge, Philip R and Yin, Yulong
Veterinary microbiology, vol. 171, (no. 1-2), pp. 160-4, 2014/Jun/25. | Journal Article
 
Influence of NleH effector expression, host genetics, and inflammation on Citrobacter rodentium colonization of mice.
Feuerbacher, Leigh Ann and Hardwidge, Philip R
Microbes and infection, vol. 16, (no. 5), pp. 429-433, May 2014. | Journal Article
2013
Escherichia coli virulence protein NleH1 interaction with the v-Crk sarcoma virus CT10 oncogene-like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/nuclear factor κB (NF-κB) pathway.
Pham, Thanh HGao, XiaofeiSingh, Gyanendra and Hardwidge, Philip R
The Journal of biological chemistry, vol. 288, (no. 48), pp. 34567-74, 2013/Nov/29. | Journal Article
 
NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NF-κB activation.
Gao, XiaofeiWang, XiaogangPham, Thanh HFeuerbacher, Leigh ALubos, Marie-LuiseHuang, MinzhaoOlsen, RachelMushegian, ArcadySlawson, Chad and Hardwidge, Philip R
Cell host & microbe, vol. 13, (no. 1), pp. 87-99, 2013/Jan/16. | Journal Article
 
The enterohemorrhagic Escherichia coli effector protein NleF binds mammalian Tmp21.
Olsen, Rachel LEchtenkamp, FrankCheranova, DilyaraDeng, WanyinFinlay, B B and Hardwidge, Philip R
Veterinary microbiology, vol. 164, (no. 1-2), pp. 164-70, 2013/May/31. | Journal Article
2012
Enterotoxigenic Escherichia coli prevents host NF-κB activation by targeting IκBα polyubiquitination.
Wang, Xiaogang and Hardwidge, Philip R
Infection and immunity, vol. 80, (no. 12), pp. 4417-25, 2012/Dec. | Journal Article
 
Functional Differences and Interactions between the Escherichia coli Type III Secretion System Effectors NleH1 and NleH2
Pham, Thanh HPham, Thanh HGao, XiaofeiGao, XiaofeiTsai, KarenTsai, KarenOlsen, RachelOlsen, RachelWan, FengyiWan, FengyiHardwidge, Philip R and Hardwidge, Philip R
Infection and Immunity, vol. 80, (no. 6), pp. 2133-2140, 2012. | Journal Article
 
Heat-labile enterotoxin-induced activation of NF-κB and MAPK pathways in intestinal epithelial cells impacts enterotoxigenic Escherichia coli (ETEC) adherence.
Wang, XiaogangGao, Xiaofei and Hardwidge, Philip R
Cellular microbiology, vol. 14, (no. 8), pp. 1231-41, 2012/Aug. | Journal Article
2011
Application of a split luciferase complementation assay for the detection of viral protein-protein interactions
Deng, QijiWang, DanXiang, XiaoxiaoGao, XiaofeiHardwidge, Philip RKaushik, Radhey SWolff, ThorstenChakravarty, Suvobrata and Li, Feng
Journal of Virological Methods, vol. 176, (no. 1-2), pp. 108-111, 2011. | Journal Article
 
IKK beta phosphorylation regulates RPS3 nuclear translocation and NF- Kappa B function during infection with Escherichia coli strain O157:H7
Wan, FengyiWeaver, AmandaGao, XiaofeiBern, MichaelHardwidge, Philip R and Lenardo, Michael J
Nature Immunology, vol. 12, (no. 4), pp. 335-343, 2011. | Journal Article
 
IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7.
Wan, FengyiWeaver, AmandaGao, XiaofeiBern, MichaelHardwidge, Philip R and Lenardo, Michael J
Nature immunology, vol. 12, (no. 4), pp. 335-43, 2011/Apr. | Journal Article
 
Nuclear localization of influenza B polymerase proteins and their binary complexes
Deng, QijiWang, DanXiang, XiaoxiaoGao, XiaofeiHardwidge, Philip RKaushik, RadheyWolff, ThorstenChakravarty, Suvobrata and Li, Feng
Virus Research, vol. 156, (no. 1-2), pp. 49-53, 2011. | Journal Article
 
Ribosomal protein s3: a multifunctional target of attaching/effacing bacterial pathogens.
Gao, Xiaofei and Hardwidge, Philip R
Frontiers in microbiology, vol. 2, pp. 137, 2011. | Journal Article
2010
Disruption of transepithelial resistance by enterotoxigenic Escherichia coli.
Johnson, Amber MKaushik, Radhey S and Hardwidge, Philip R
Veterinary microbiology, vol. 141, (no. 1-2), pp. 115-9, 2010/Feb/24. | Journal Article
 
Molecular mechanisms of enterotoxigenic Escherichia coli infection.
Fleckenstein, James MHardwidge, Philip RMunson, George PRasko, David ASommerfelt, Halvor and Steinsland, Hans
Microbes and infection / Institut Pasteur, vol. 12, (no. 2), pp. 89-98, 2010/Feb. | Journal Article
 
The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling.
Shames, Stephanie RDeng, WanyinGuttman, Juliande Hoog, Carmen LLi, YulingHardwidge, Philip RSham, Ho PVallance, BruceFoster, Leonard and Finlay, B B
Cellular microbiology, vol. 12, (no. 9), pp. 1322-39, 2010/Sep/1. | Journal Article
2009
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function.
Gao, XiaofeiGao, XiaofeiWan, FengyiWan, FengyiMateo, KristinaMateo, KristinaCallegari, EduardoCallegari, EduardoWang, DanWang, DanDeng, WanyinDeng, WanyinPuente, JosePuente, JoseLi, FengLi, FengChaussee, Michael SChaussee, Michael SFinlay, B BFinlay, B BrettLenardo, Michael JLenardo, Michael JHardwidge, Philip R and Hardwidge, Philip R
PLoS pathogens, vol. 5, (no. 12), pp. e1000708, 2009/Dec. | Journal Article