My research interests lie in the adaptation of the cardiovascular system to ischemic insult. For example, we are currently investigating the participation of an oxidant-generating enzyme of neutrophils and other cells (NADPH oxidase) in ischemia-reperfusion injury,and the degree to which injury can be limited by inhibition of the NADPH oxidase. Proline-arginine -rich antimicrobial peptides with oxidase blocking activities are agents of particular interest.
My research interests lie in the interaction of the cardiovascular system with innate immune mechanisms. For example, we are currently investigating the participation of an oxidant-generating enzyme (NADPH oxidase) in inflammatory cell injury, and the degree to which injury can be limited by inhibition of the NADPH oxidase by antimicrobial peptides. Other interests include the participation of antimicrobial peptides in protection from bovine pinkeye.
My research interests lie in the adaptation of the cardiovascular system to ischemic insult. For example, we are currently investigating the participation of an oxidant-generating enzyme of neutrophils and other cells (NADPH oxidase) in ischemia-reperfusion injury,and the degree to which injury can be limited by inhibition of the NADPH oxidase. Proline-arginine -rich antimicrobial peptides with oxidase blocking activities are agents of particular interest.
Antimicrobial Peptides, Innate Immunity
