176 Publications (Page 4 of 8)
2008
Synthesis and anti-breast cancer activities of substituted quinolinesShi, Aibin⋅Nguyen, Thu A⋅Battina, Srinivas K⋅Rana, Sandeep⋅Takemoto, Dolores J⋅Chiang, Peter K and Hua, Duy HBioorganic and Medicinal Chemistry, vol. 18, (no. 11), pp. 3364-3368, 2008.
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Total syntheses of (+/-)-ovalicin, C4(S *)-isomer, and its C5-analogs and anti-trypanosomal activities.Hua, Duy H⋅Zhao, Huiping⋅Battina, Srinivas K⋅Lou, Kaiyan⋅Jimenez, Ana L⋅Desper, John⋅Perchellet, Elisabeth M⋅Perchellet, Jean Pierre H and Chiang, Peter KBioorganic & medicinal chemistry, vol. 16, (no. 9), pp. 5232-46, 2008/May/1.
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Total syntheses of (+/-)-ovalicin, C4(S super(*))-isomer, and its C5- analogs and anti-trypanosomal activitiesHua, Duy H⋅Zhao, Huiping⋅Battina, Srinivas K⋅Lou, Kaiyan⋅Jimenez, Ana L⋅Desper, John⋅Perchellet, Elisabeth M⋅Perchellet, Jean Pierre H and Chiang, Peter KBioorganic and Medicinal Chemistry, vol. 16, (no. 9), pp. 5232-5246, 2008.
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2007
Antitumor triptycene analogs directly interact with isolated mitochondria to rapidly trigger markers of permeability transition.Perchellet, Elisabeth M⋅Wang, Yang⋅Lou, Kaiyan⋅Zhao, Huiping⋅Battina, Srinivas K⋅Hua, Duy H and Perchellet, Jean Pierre HAnticancer research, vol. 27, (no. 5A), pp. 3259-71, 2007 Sep-Oct.
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Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of A beta oligomer-induced cytotoxicityHong, HS⋅Maezawa, I.⋅Yao, N.⋅Xu, B.⋅Diaz-Avalos, R.⋅Rana, S.⋅Hua, Duy H⋅Cheng, RH⋅Lam, Kit S and Jin, Lee WayBrain Research, vol. 1130, (no. 1), pp. 223-234, 2007.
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Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Abeta oligomer-induced cytotoxicity.Hong, Hyun-Seok⋅Maezawa, Izumi⋅Yao, Nianhuan⋅Xu, Bailing⋅Diaz-Avalos, Ruben⋅Rana, Sandeep⋅Hua, Duy H⋅Cheng, R H⋅Lam, Kit S and Jin, Lee WayBrain research, vol. 1130, (no. 1), pp. 223-34, 2007/Jan/26.
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Novel substituted 1,4-anthracenediones with antitumor activity directly induce permeability transition in isolated mitochondria.Perchellet, Elisabeth M⋅Wang, Yang⋅Lou, Kaiyan⋅Zhao, Huiping⋅Battina, Srinivas K⋅Hua, Duy H and Perchellet, Jean Pierre HInternational journal of oncology, vol. 31, (no. 5), pp. 1231-41, 2007/Nov.
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Structure and function of eritadenine and its 3-deaza analogues: Potent inhibitors of S-adenosylhomocysteine hydrolase and hypocholesterolemic agentsYamada, Taro⋅Yamada, Taro⋅Komoto, Junichi⋅Komoto, Junichi⋅Lou, Kaiyan⋅Lou, Kaiyan⋅Ueki, Akiharu⋅Ueki, Akiharu⋅Hua, Duy H.⋅Hua, Duy H⋅Sugiyama, Kimio⋅Sugiyama, Kimio⋅Takata, Yoshimi⋅Takata, Yoshimi⋅Ogawa, Hirofumi⋅Ogawa, Hirofumi⋅Takusagawa, Fusao and Takusagawa, FusaoBiochemical pharmacology, vol. 73, (no. 7), pp. 989, 2007-04-01.
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2006
A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid-[beta] oligomeric complexesMaezawa, Izumi⋅Hong, Hyun-Seok⋅Wu, Hui-Chuan⋅Battina, Srinivas K⋅Rana, Sandeep⋅Iwamoto, Takeo⋅Radke, Gary A⋅Pettersson, Erik⋅Martin, George M⋅Hua, Duy H and Jin, Lee WayJournal of Neurochemistry, vol. 98, (no. 1), pp. 57-67, Jul 2006.
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Antitumor triptycene analogs induce a rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria.Wang, Yang⋅Perchellet, Elisabeth M⋅Ward, Mary M⋅Lou, Kaiyan⋅Zhao, Huiping⋅Battina, Srinivas K⋅Wiredu, Bernard⋅Hua, Duy H and Perchellet, Jean Pierre HInternational journal of oncology, vol. 28, (no. 1), pp. 161-72, 2006/Jan.
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Preparation and Characterization of Nanofibrous Perylene-Diimide−Polyelectrolyte Composite Thin FilmsEverett, Thomas A⋅Twite, Amy A⋅Xie, Aifang⋅Battina, Srinivas K⋅Hua, Duy H and Higgins, Daniel AChemistry of materials, vol. 18, (no. 25), pp. 5943, 2006-12-12.
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Syntheses, Molecular Targets and Antitumor Activities of Novel Triptycene Bisquinones and 1,4-Anthracenedione AnalogsHua, Duy H⋅Lou, Kaiyan⋅Battina, Srinivas K⋅Zhao, Huiping⋅Perchellet, Elisabeth M⋅Wang, Yang and Perchellet, Jean Pierre HAnti-Cancer Agents in Medicinal Chemistry, vol. 6, (no. 4), pp. 303-318, 2006.
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2005
Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones.Wang, Yang⋅Perchellet, Elisabeth M⋅Ward, Mary M⋅Lou, Kaiyan⋅Hua, Duy H and Perchellet, Jean Pierre HAnti-cancer drugs, vol. 16, (no. 9), pp. 953-67, 2005/Oct.
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Synthesis and in vitro Antitumor Activity of Substituted Anthracene-1,4-dionesHua, Duy H.⋅Lou, Kaiyan⋅Havens, Josh⋅Perchellet, Elisabeth M.⋅Wang, Yang⋅Perchellet, Jean-Pierre and Iwamoto, TakeoChemInform, vol. 36, (no. 8), pp. no, 2005-02-22.
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Total Syntheses of (+)-Chloropuupehenone (I) and (+)-Chloropuupehenol (II) and Their Analogues and Evaluation of Their BioactivitiesHua, Duy H. and ., et alChemInform, vol. 36, (no. 1), pp. no, 2005-01-04.
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2004
Antitumor triptycene bisquinones induce a caspase-independent release of mitochondrial cytochrome c and a caspase-2-mediated activation of initiator caspase-8 and -9 in HL-60 cells by a mechanism which does not involve Fas signaling.Perchellet, Elisabeth M⋅Wang, Yang⋅Weber, Rebeka L⋅Lou, Kaiyan⋅Hua, Duy H and Perchellet, Jean Pierre HAnti-cancer drugs, vol. 15, (no. 10), pp. 929-46, 2004/Nov.
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Synthesis and in vitro antitumor activity of substituted anthracene-1,4-dionesHua, Duy H.⋅Lou, Kaiyan⋅Havens, Josh⋅Perchellet, Elisabeth M.⋅Wang, Yang⋅Perchellet, Jean-Pierre and Iwamoto, TakeoTetrahedron, vol. 60, (no. 45), pp. 10163, 2004-11-01.
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Synthetic 1,4-anthracenedione analogs induce cytochrome c release, caspase-9, -3, and -8 activities, poly(ADP-ribose) polymerase-1 cleavage and internucleosomal DNA fragmentation in HL-60 cells by a mechanism which involves caspase-2 activation but not Fas signaling.Perchellet, Elisabeth M⋅Wang, Yang⋅Weber, Rebeka L⋅Sperfslage, Bonnie J⋅Lou, Kaiyan⋅Crossland, Justin⋅Hua, Duy H and Perchellet, Jean Pierre HBiochemical pharmacology, vol. 67, (no. 3), pp. 523-37, 2004/Feb/1.
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Total syntheses of (+)-chloropuupehenone and (+)-chloropuupehenol and their analogues and evaluation of their bioactivities.Hua, Duy H⋅Huang, Xiaodong⋅Chen, Yi⋅Battina, Srinivas K⋅Tamura, Masafumi⋅Noh, Sang K⋅Koo, Sung I⋅Namatame, Ichiji⋅Tomoda, Hiroshi⋅Perchellet, Elisabeth M and Perchellet, Jean Pierre HThe Journal of organic chemistry, vol. 69, (no. 18), pp. 6065-78, 2004/Sep/3.
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2003
Antiprotozoal activities of symmetrical bishydroxamic acids.Hua, Duy H⋅Tamura, Masafumi⋅Egi, Masahiro⋅Werbovetz, Karl A⋅Delfín, Dawn⋅Salem, Manar and Chiang, Peter KBioorganic & medicinal chemistry, vol. 11, (no. 20), pp. 4357-61, 2003/Oct/1.
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Antitumor triptycene bisquinones: a novel synthetic class of dual inhibitors of DNA topoisomerase I and II activities.Wang, Buna⋅Perchellet, Elisabeth M⋅Wang, Yang⋅Tamura, Masafumi⋅Hua, Duy H and Perchellet, Jean Pierre HAnti-cancer drugs, vol. 14, (no. 7), pp. 503-14, 2003/Aug.
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Parallel and perpendicular stacking of ferrocene ringsHua, Duy H.⋅McGill, James W.⋅Lou, Kaiyan⋅Ueki, Akiharu⋅Helfrich, Brian⋅Desper, John⋅Zanello, Piero⋅Cinquantini, Arnaldo⋅Corsini, Maddalena and Fontani, MarcoInorganica Chimica Acta, vol. 350, pp. 265, 2003-7-00.
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Syntheses and bioactivities of tricyclic pyronesHua, Duy H⋅Huang, Xiaodong⋅Tamura, Masafumi⋅Chen, Yi⋅Woltkamp, Melissa⋅Jin, Lee-Way⋅Perchellet, Elisabeth M⋅Perchellet, Jean-Pierre⋅Chiang, Peter K⋅Namatame, Ichiji and Tomoda, HiroshiTetrahedron, vol. 59, (no. 26), pp. 4803, 2003-06-23.
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Unexpected Differences in the α-Halogenation and Related Reactivity of Sulfones with Perhaloalkanes in KOH-t-BuOHMeyers, Cal Y.⋅Chan-Yu-King, Roch⋅Hua, Duy H.⋅Kolb, Vera M.⋅Matthews, Walter S.⋅Parady, Thomas E.⋅Horii, Toyokazu⋅Sandrock, Paul B.⋅Hou, Yuqing and Xie, SongwenChemInform, vol. 34, (no. 22), pp. no, 2003-06-03.
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Unexpected Differences in the α-Halogenation and Related Reactivity of Sulfones with Perhaloalkanes in KOH−t-BuOHMeyers, Cal Y⋅Chan-Yu-King, Roch⋅Hua, Duy H⋅Kolb, Vera M⋅Matthews, Walter S⋅Parady, Thomas E⋅Horii, Toyokazu⋅Sandrock, Paul B⋅Hou, Yuqing and Xie, SongwenJournal of organic chemistry, vol. 68, (no. 2), pp. 511, 2003-01-24.
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