54 Publications (Page 1 of 3)
2021
Arginine glycosylation enhances methylglyoxal detoxification
El Qaidi, Samir⋅Scott, Nichollas E⋅Scott, Nichollas E⋅Hardwidge, Philip R and Hardwidge, Philip R
Scientific Reports (Nature Publisher Group), vol. 11, (no. 1), 2021. | Journal Article
 
The Role of Innate Immunity in Pulmonary Infections
Zhang, Huihui⋅He, Fang⋅Pan, Li⋅Hardwidge, Philip R⋅Li, Nengzhang and Peng, Yuanyi
BioMed Research International, vol. 2021, 2021. | Journal Article
2020
An intra-bacterial activity for a T3SS effector
El Qaidi, Samir⋅Scott, Nichollas E⋅Scott, Nichollas E⋅Scott, Nichollas E⋅Hays, Michael P⋅Hays, Michael P⋅Hays, Michael P⋅Geisbrecht, Brian V⋅Geisbrecht, Brian V⋅Geisbrecht, Brian V⋅Watkins, Shelby⋅Watkins, Shelby⋅Watkins, Shelby⋅Hardwidge, Philip R⋅Hardwidge, Philip R and Hardwidge, Philip R
Scientific Reports (Nature Publisher Group), vol. 10, (no. 1), 2020. | Journal Article
2018
Isolation and Characterization of N-acyl Homoserine Lactone-Producing Bacteria From Cattle Rumen and Swine Intestines.
Yang, Yang⋅Zhou, Mingxu⋅Hardwidge, Philip R⋅Cui, Hengmi and Zhu, Guoqiang
Frontiers in cellular and infection microbiology, vol. 8, pp. 155, 2018. | Journal Article
2016
Construction and sequencing of an infectious clone of the goose embryo-adapted Muscovy duck parvovirus vaccine strain FZ91-30
Wang, Jianye⋅Wang, Jianye⋅Huang, Yu⋅Huang, Yu⋅Zhou, Mingxu⋅Zhou, Mingxu⋅Hardwidge, Philip R⋅Hardwidge, Philip R⋅Zhu, Guoqiang and Zhu, Guoqiang
Virology Journal, vol. 13, 2016. | Journal Article
2015
More than a locomotive organelle: flagella in Escherichia coli
Zhou, Mingxu⋅Yang, Yang⋅Chen, Panlin⋅Hu, Huijie⋅Hardwidge, Philip R and Zhu, Guoqiang
(pp. 8883-8890). Nov 2015
 
Protective Enterotoxigenic Escherichia coli Antigens in a Murine Intranasal Challenge Model.
Kumar, Amit⋅Hays, Mike⋅Lim, Francis⋅Foster, Leonard J⋅Zhou, Mingxu⋅Zhu, Guoqiang⋅Miesner, Tracy and Hardwidge, Philip R
PLoS neglected tropical diseases, vol. 9, (no. 8), pp. e0003924, 2015. | Journal Article
2014
'Drugs from bugs': bacterial effector proteins as promising biological (immune-) therapeutics.
Rüter, Christian and Hardwidge, Philip R
FEMS microbiology letters, vol. 351, (no. 2), pp. 126-132, February 2014. | Journal Article
 
Enterotoxigenic Escherichia coli infection induces intestinal epithelial cell autophagy.
Tang, Yulong⋅Li, Fengna⋅Tan, Bie⋅Liu, Gang⋅Kong, Xiangfeng⋅Hardwidge, Philip R and Yin, Yulong
Veterinary microbiology, vol. 171, (no. 1-2), pp. 160-4, 2014/Jun/25. | Journal Article
 
Influence of NleH effector expression, host genetics, and inflammation on Citrobacter rodentium colonization of mice.
Feuerbacher, Leigh Ann and Hardwidge, Philip R
Microbes and infection, vol. 16, (no. 5), pp. 429-433, May 2014. | Journal Article
2013
Escherichia coli virulence protein NleH1 interaction with the v-Crk sarcoma virus CT10 oncogene-like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/nuclear factor κB (NF-κB) pathway.
Pham, Thanh H⋅Gao, Xiaofei⋅Singh, Gyanendra and Hardwidge, Philip R
The Journal of biological chemistry, vol. 288, (no. 48), pp. 34567-74, 2013/Nov/29. | Journal Article
 
NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NF-κB activation.
Gao, Xiaofei⋅Wang, Xiaogang⋅Pham, Thanh H⋅Feuerbacher, Leigh A⋅Lubos, Marie-Luise⋅Huang, Minzhao⋅Olsen, Rachel⋅Mushegian, Arcady⋅Slawson, Chad and Hardwidge, Philip R
Cell host & microbe, vol. 13, (no. 1), pp. 87-99, 2013/Jan/16. | Journal Article
 
The enterohemorrhagic Escherichia coli effector protein NleF binds mammalian Tmp21.
Olsen, Rachel L⋅Echtenkamp, Frank⋅Cheranova, Dilyara⋅Deng, Wanyin⋅Finlay, B B and Hardwidge, Philip R
Veterinary microbiology, vol. 164, (no. 1-2), pp. 164-70, 2013/May/31. | Journal Article
2012
Enterotoxigenic Escherichia coli prevents host NF-κB activation by targeting IκBα polyubiquitination.
Wang, Xiaogang and Hardwidge, Philip R
Infection and immunity, vol. 80, (no. 12), pp. 4417-25, 2012/Dec. | Journal Article
 
Functional Differences and Interactions between the Escherichia coli Type III Secretion System Effectors NleH1 and NleH2
Pham, Thanh H⋅Pham, Thanh H⋅Gao, Xiaofei⋅Gao, Xiaofei⋅Tsai, Karen⋅Tsai, Karen⋅Olsen, Rachel⋅Olsen, Rachel⋅Wan, Fengyi⋅Wan, Fengyi⋅Hardwidge, Philip R and Hardwidge, Philip R
Infection and Immunity, vol. 80, (no. 6), pp. 2133-2140, 2012. | Journal Article
 
Heat-labile enterotoxin-induced activation of NF-κB and MAPK pathways in intestinal epithelial cells impacts enterotoxigenic Escherichia coli (ETEC) adherence.
Wang, Xiaogang⋅Gao, Xiaofei and Hardwidge, Philip R
Cellular microbiology, vol. 14, (no. 8), pp. 1231-41, 2012/Aug. | Journal Article
2011
Application of a split luciferase complementation assay for the detection of viral protein-protein interactions
Deng, Qiji⋅Wang, Dan⋅Xiang, Xiaoxiao⋅Gao, Xiaofei⋅Hardwidge, Philip R⋅Kaushik, Radhey S⋅Wolff, Thorsten⋅Chakravarty, Suvobrata and Li, Feng
Journal of Virological Methods, vol. 176, (no. 1-2), pp. 108-111, 2011. | Journal Article
 
IKK beta phosphorylation regulates RPS3 nuclear translocation and NF- Kappa B function during infection with Escherichia coli strain O157:H7
Wan, Fengyi⋅Weaver, Amanda⋅Gao, Xiaofei⋅Bern, Michael⋅Hardwidge, Philip R and Lenardo, Michael J
Nature Immunology, vol. 12, (no. 4), pp. 335-343, 2011. | Journal Article
 
IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7.
Wan, Fengyi⋅Weaver, Amanda⋅Gao, Xiaofei⋅Bern, Michael⋅Hardwidge, Philip R and Lenardo, Michael J
Nature immunology, vol. 12, (no. 4), pp. 335-43, 2011/Apr. | Journal Article
 
Nuclear localization of influenza B polymerase proteins and their binary complexes
Deng, Qiji⋅Wang, Dan⋅Xiang, Xiaoxiao⋅Gao, Xiaofei⋅Hardwidge, Philip R⋅Kaushik, Radhey⋅Wolff, Thorsten⋅Chakravarty, Suvobrata and Li, Feng
Virus Research, vol. 156, (no. 1-2), pp. 49-53, 2011. | Journal Article
 
Ribosomal protein s3: a multifunctional target of attaching/effacing bacterial pathogens.
Gao, Xiaofei and Hardwidge, Philip R
Frontiers in microbiology, vol. 2, pp. 137, 2011. | Journal Article
2010
Disruption of transepithelial resistance by enterotoxigenic Escherichia coli.
Johnson, Amber M⋅Kaushik, Radhey S and Hardwidge, Philip R
Veterinary microbiology, vol. 141, (no. 1-2), pp. 115-9, 2010/Feb/24. | Journal Article
 
Molecular mechanisms of enterotoxigenic Escherichia coli infection.
Fleckenstein, James M⋅Hardwidge, Philip R⋅Munson, George P⋅Rasko, David A⋅Sommerfelt, Halvor and Steinsland, Hans
Microbes and infection / Institut Pasteur, vol. 12, (no. 2), pp. 89-98, 2010/Feb. | Journal Article
 
The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling.
Shames, Stephanie R⋅Deng, Wanyin⋅Guttman, Julian⋅de Hoog, Carmen L⋅Li, Yuling⋅Hardwidge, Philip R⋅Sham, Ho P⋅Vallance, Bruce⋅Foster, Leonard and Finlay, B B
Cellular microbiology, vol. 12, (no. 9), pp. 1322-39, 2010/Sep/1. | Journal Article
2009
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function.
Gao, Xiaofei⋅Gao, Xiaofei⋅Wan, Fengyi⋅Wan, Fengyi⋅Mateo, Kristina⋅Mateo, Kristina⋅Callegari, Eduardo⋅Callegari, Eduardo⋅Wang, Dan⋅Wang, Dan⋅Deng, Wanyin⋅Deng, Wanyin⋅Puente, Jose⋅Puente, Jose⋅Li, Feng⋅Li, Feng⋅Chaussee, Michael S⋅Chaussee, Michael S⋅Finlay, B B⋅Finlay, B Brett⋅Lenardo, Michael J⋅Lenardo, Michael J⋅Hardwidge, Philip R and Hardwidge, Philip R
PLoS pathogens, vol. 5, (no. 12), pp. e1000708, 2009/Dec. | Journal Article