16 Publications
2022
Analytical Validation of a Computational Method for Pharmacogenetic Genotyping from Clinical Whole Exome Sequencing
Ly, Reynold C.⋅Shugg, Tyler⋅Ratcliff, Ryan⋅Osei, Wilberforce⋅Lynnes, Ty C.⋅Pratt, Victoria M.⋅Schneider, Bryan P.⋅Radovich, Milan⋅Bray, Steven M.⋅Salisbury, Benjamin A.⋅Parikh, Baiju⋅Sahinalp, S. Cenk⋅Numanagić, Ibrahim and Skaar, Todd C.
Elsevier BV
 
Association of QT interval-prolonging drugs with clinical trial eligibility in patients with advanced cancer. Frontiers in cardiovascular medicine
Rowe, Elizabeth J⋅Rowe, Elizabeth J⋅Rowe, Elizabeth J⋅Shugg, Tyler⋅Shugg, Tyler⋅Shugg, Tyler⋅Ly, Reynold C⋅Ly, Reynold C⋅Ly, Reynold C⋅Philips, Santosh⋅Philips, Santosh⋅Philips, Santosh⋅Rosenman, Marc B⋅Rosenman, Marc B⋅Rosenman, Marc B⋅Callaghan, John T⋅Callaghan, John T⋅Callaghan, John T⋅Radovich, Milan⋅Radovich, Milan⋅Radovich, Milan⋅Overholser, Brian R⋅Overholser, Brian R⋅Overholser, Brian R⋅Schneider, Bryan P⋅Schneider, Bryan P⋅Schneider, Bryan P⋅Tisdale, James E⋅Tisdale, James E⋅Tisdale, James E⋅Skaar, Todd C⋅Skaar, Todd C and Skaar, Todd C
. | Journal Article
 
Clinical Opportunities for Germline Pharmacogenetics and Management of Drug-Drug Interactions in Patients With Advanced Solid Cancers
Shugg, Tyler⋅Shugg, Tyler⋅Shugg, Tyler⋅Ly, Reynold C.⋅Ly, Reynold C⋅Ly, Reynold C⋅Rowe, Elizabeth J⋅Rowe, Elizabeth J⋅Rowe, Elizabeth J.⋅Philips, Santosh⋅Philips, Santosh⋅Philips, Santosh⋅Hyder, Mustafa A.⋅Hyder, Mustafa A⋅Hyder, Mustafa A⋅Radovich, Milan⋅Radovich, Milan⋅Radovich, Milan⋅Rosenman, Marc B⋅Rosenman, Marc B.⋅Rosenman, Marc B⋅Pratt, Victoria M⋅Pratt, Victoria M.⋅Pratt, Victoria M⋅Callaghan, John T⋅Callaghan, John T.⋅Callaghan, John T⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Schneider, Bryan P⋅Schneider, Bryan P⋅Schneider, Bryan P.⋅Skaar, Todd C.⋅Skaar, Todd C and Skaar, Todd C
American Society of Clinical Oncology (ASCO)
 
Comparison of clinical pharmacogenetic recommendations across therapeutic areas
Shugg, Tyler⋅Pasternak, Amy L. and Luzum, Jasmine A.
(pp. 51–59). Ovid Technologies (Wolters Kluwer Health)
 
Evaluation of U.S. food and drug administration drug label recommendations for co‐administration of antivirals and acid reducing agents. Clinical Pharmacology & Therapeutics
 
Life-Threatening Docetaxel Toxicity in a Patient With Reduced-Function CYP3A Variants: A Case Report. Frontiers in Oncology
Powell, Nicholas R⋅Powell, Nicholas R.⋅Shugg, Tyler⋅Shugg, Tyler⋅Ly, Reynold C⋅Ly, Reynold C.⋅Albany, Costantine⋅Albany, Costantine⋅Radovich, Milan⋅Radovich, Milan⋅Schneider, Bryan P⋅Schneider, Bryan P.⋅Skaar, Todd C. and Skaar, Todd C
2021
CLINICAL OPPORTUNITIES FOR GERMLINE PHARMACOGENETICS AND MANAGEMENT OF DRUG-DRUG INTERACTIONS IN PATIENTS WITH ADVANCED SOLID CANCERS
Shugg, Tyler⋅Ly, Reynold C⋅Rowe, Elizabeth J⋅Philips, Santosh⋅Hyder, Mustafa A⋅Radovich, Milan⋅Rosenman, Marc B⋅Pratt, Victoria M⋅Callaghan, John T⋅Desta, Zeruesenay⋅Schneider, Bryan P and Skaar, Todd C
Cold Spring Harbor Laboratory
2020
Inhibition of Human Ether-A-Go-Go-Related Gene (hERG) Potassium Current by the Novel Sotalol Analogue, Soestalol. JACC. Clinical electrophysiology
Shugg, Tyler⋅Somberg, John C.⋅Molnar, Janos and Overholser, Brian R.
 
Letrozole targets the human ether-a-go-go-related gene potassium current in glioblastoma. Basic & clinical pharmacology & toxicology
Shugg, Tyler⋅Dave, Nimita⋅Amarh, Enoch⋅Assiri, Abdullah A.⋅Pollok, Karen E. and Overholser, Brian R.
 
Neurohormonal Regulation of IKs in Heart Failure: Implications for Ventricular Arrhythmogenesis and Sudden Cardiac Death. Journal of the American Heart Association
 
Prevalence and types of inconsistencies in clinical pharmacogenetic recommendations among major U.S. sources. NPJ genomic medicine
2019
Association of Regulatory Genetic Variants for Protein Kinase Cα with Mortality and Drug Efficacy in Patients with Heart Failure. Cardiovascular drugs and therapy
 
Progesterone Metabolites Inhibit the Human Ether-a-go-go-Related Gene and Predict QT Interval Length. Journal of clinical pharmacology
Shugg, Tyler⋅Shugg, Tyler⋅Egly, Christian⋅Egly, Christian⋅Stamatkin, Chris W.⋅Stamatkin, Chris W.⋅Patil, Avinash S.⋅Patil, Avinash S.⋅Tisdale, James E.⋅Tisdale, James E.⋅Overholser, Brian R. and Overholser, Brian R.
2018
Calcium/calmodulin-dependent protein kinase II regulation of IKs during sustained β-adrenergic receptor stimulation. Heart rhythm
Shugg, Tyler⋅Shugg, Tyler⋅Shugg, Tyler⋅Shugg, Tyler⋅Johnson, Derrick E⋅Johnson, Derrick⋅Johnson, Derrick E⋅Johnson, Derrick E⋅Shao, Minghai⋅Shao, Minghai⋅Shao, Minghai⋅Shao, Minghai⋅Lai, Xianyin⋅Lai, Xianyin⋅Lai, Xianyin⋅Lai, Xianyin⋅Witzmann, Frank⋅Witzmann, Frank⋅Witzmann, Frank⋅Witzmann, Frank⋅Cummins, Theodore R⋅Cummins, Theodore R⋅Cummins, Theodore R⋅Cummins, Theodore⋅Rubart-Von-der Lohe, Michael⋅Rubart-Von-der Lohe, Michael⋅Rubart-Von-der Lohe, Michael⋅Rubart-Von-der Lohe, Michael⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Overholser, Brian⋅Overholser, Brian R⋅Overholser, Brian R and Overholser, Brian R
2016
Efavirenz Inhibits the Human Ether-A-Go-Go Related Current (hERG) and Induces QT Interval Prolongation in CYP2B6*6*6 Allele Carriers. Journal of cardiovascular electrophysiology
ABDELHADY, AHMED M.⋅Abdelhady, Ahmed M⋅SHUGG, TYLER⋅Shugg, Tyler⋅THONG, NANCY⋅Thong, Nancy⋅Lu, Jessica Bo Li⋅LU, JESSICA BO LI⋅KREUTZ, YVONNE⋅Kreutz, Yvonne⋅JAYNES, HEATHER A.⋅Jaynes, Heather A⋅Robarge, Jason D⋅ROBARGE, JASON D.⋅TISDALE, JAMES E.⋅Tisdale, James E⋅DESTA, ZERUESENAY⋅Desta, Zeruesenay⋅Overholser, Brian R. and Overholser, Brian R
2010
Zwitterionic chitosan derivatives for pH-sensitive stealth coating. Biomacromolecules
Xu, Peisheng⋅Bajaj, Gaurav⋅Shugg, Tyler⋅Van Alstine, William G and Yeo, Yoon