Our laboratory is interested in studying the genetics of metabolic function and disease through the manipulation of genetic model systems, particularly the mouse and the fruit fly, Drosophila melanogaster. Specifically, we are interested in the function of the mitochondrion in normal cellular biology and disease. By taking advantage of the strengths of each model system, we intend to dissect the pathophysiology of mitochondrial dysfunction to progress towards the ultimate goal of developing novel therapeutic strategies for diseases that exhibit mitochondrial dysfunction.
Clinical Interests:
- Mitochondrial Disorders; Inborn Errors of Metabolism; Clinical Genetics
