128 Publications (Page 4 of 6)
2006
SME-3, a Novel Member of the Serratia marcescens SME Family of Carbapenem-Hydrolyzing β-Lactamases
Queenan, AnneShang, WenchiSchreckenberger, PaulLolans, KarenBush, Karen and Quinn, John
Antimicrobial Agents and Chemotherapy, vol. 50, (no. 10), pp. 3487, 20061001. | Journal Article
 
Synthesis and antibacterial activity of 6- O-heteroarylcarbamoyl-11,12-lactoketolides
Grant, Eugene BGuiadeen, DeodialsinghAbbanat, DarrenFoleno, Barbara DBush, Karen and Macielag, Mark J
Bioorganic & Medicinal Chemistry Letters, vol. 16, (no. 7), pp. 1933, 2006. | Journal Article
 
Synthesis and Antibacterial Activity of 6-O-Heteroarylcarbamoyl-11,12-lactoketolides
Grant, Eugene BGuiadeen, DeodialsinghAbbanat, DarrenFoleno, Barbara DBush, Karen and Macielag, Mark J
ChemInform, vol. 37, (no. 28), 2006-07-11. | Journal Article
 
Synthesis and antibacterial activity of C6-carbazate ketolides
Tennakoon, Manomi AHenninger, Todd CAbbanat, DarrenFoleno, Barbara DHilliard, Jamese JBush, Karen and Macielag, Mark J
Bioorganic and Medicinal Chemistry Letters, vol. 16, (no. 24), pp. 6231-6235, 2006. | Journal Article
 
Utility of Muropeptide Ligase for Identification of Inhibitors of the Cell Wall Biosynthesis Enzyme MurF
Baum, EllenCrespo-Carbone, StevenAbbanat, DarrenFoleno, BarbaraMaden, AmyGoldschmidt, Raul and Bush, Karen
Antimicrobial Agents and Chemotherapy, vol. 50, (no. 1), pp. 236, 20060101. | Journal Article
2005
15-Amido Erythromycins: Synthesis and in vitro Activity of a New Class of Macrolide Antibiotics
Shaw, Simon JAbbanat, DarrenAshley, Gary WBush, KarenFoleno, BarbaraMacielag, MarkZhang, Dan and Myles, David C
ChemInform, vol. 36, (no. 39), 2005-09-27. | Journal Article
 
15-Amido Erythromycins: Synthesis and in Vitro Activity of a New Class of Macrolide Antibiotics
Shaw, Simon JAbbanat, DarrenAshley, Gary WBush, KarenFoleno, BarbaraMacielag, MarkZhang, Dan and Myles, David C
The Journal of antibiotics, vol. 58, (no. 3), pp. 177, 2005-Mar. | Journal Article
 
Beta-lactamase nomenclature
Jacoby, George A and Bush, Karen
Journal of clinical microbiology, vol. 43, (no. 12), pp. 6220, 2005-Dec. | Journal Article
 
Effective Antimicrobial Regimens for Use in Humans for Therapy of Bacillus anthracis Infections and Postexposure Prophylaxis
Deziel, MarkHeine, HenryLouie, ArnoldKao, MarkByrne, WilliamBasset, JenniferMiller, LyndaBush, KarenKelly, Michael and Drusano, G.
Antimicrobial Agents and Chemotherapy, vol. 49, (no. 12), pp. 5106, 20051201. | Journal Article
 
Identification of a Dithiazoline Inhibitor of Escherichia coli l,d-Carboxypeptidase A
Baum, EllenCrespo-Carbone, StevenFoleno, BarbaraPeng, SeanHilliard, JameseAbbanat, DarrenGoldschmidt, Raul and Bush, Karen
Antimicrobial Agents and Chemotherapy, vol. 49, (no. 11), pp. 4507, 20051101. | Journal Article
 
Predominance of 23S rRNA Mutants among Non-Erm, Non-Mef Macrolide-Resistant Clinical Isolates of Streptococcus pneumoniae Collected in the United States in 1999-2000
Davies, ToddBush, KarenSahm, Daniel and Evangelista, Alan
Antimicrobial Agents and Chemotherapy, vol. 49, (no. 7), pp. 3033, 20050701. | Journal Article
2004
Effects of Inoculum and β-Lactamase Activity in AmpC- and Extended-Spectrum β-Lactamase (ESBL)-Producing Escherichia coli and Klebsiella pneumoniae Clinical Isolates Tested by Using NCCLS ESBL Methodology
Queenan, AnneFoleno, BarbaraGownley, ColleenWira, Ellyn and Bush, Karen
Journal of Clinical Microbiology, vol. 42, (no. 1), pp. 275, 20040101. | Journal Article
 
Synthesis and antibacterial activity of C-6 carbamate ketolides, a novel series of orally active ketolide antibiotics
Henninger, Todd CXu, XiaodongAbbanat, DarrenBaum, Ellen ZFoleno, Barbara DHilliard, Jamese JBush, KarenHlasta, Dennis J and Macielag, Mark J
Bioorganic & Medicinal Chemistry Letters, vol. 14, (no. 17), pp. 4499, 2004. | Journal Article
 
Synthesis and Antibacterial Activity of C-6 Carbamate Ketolides, a Novel Series of Orally Active Ketolide Antibiotics
Henninger, Todd CXu, XiaodongAbbanat, DarrenBaum, Ellen ZFoleno, Barbara DHilliard, Jamese JBush, KarenHlasta, Dennis J and Macielag, Mark J
ChemInform, vol. 35, (no. 52), 2004-12-28. | Journal Article
 
The synthesis and antimicrobial evaluation of a new series of isoxazolinyl oxazolidinones
Weidner-Wells, Michele AWerblood, Harvey MGoldschmidt, RaulBush, KarenFoleno, Barbara DHilliard, Jamese JMelton, JohnWira, Ellyn and Macielag, Mark J
Bioorganic & Medicinal Chemistry Letters, vol. 14, (no. 12), pp. 3072, 2004. | Journal Article
 
The Synthesis and Antimicrobial Evaluation of a New Series of isoxazolinyl Oxazolidinones
Weidner-Wells, Michele AWerblood, Harvey MGoldschmidt, RaulBush, KarenFoleno, Barbara DHilliard, Jamese JMelton, JohnWira, Ellyn and Macielag, Mark J
ChemInform, vol. 35, (no. 40), 2004-10-05. | Journal Article
2003
Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy
Jumbe, NelsonJumbe, NelsonLouie, ArnoldLouie, ArnoldLeary, RobertLeary, RobertLiu, WeiguoLiu, WeiguoDeziel, Mark RDeziel, Mark RTam, Vincent HTam, Vincent HBachhawat, ReetuBachhawat, ReetuFreeman, ChristopherFreeman, ChristopherKahn, James BKahn, James BBush, KarenBush, KarenDudley, Michael NDudley, Michael NMiller, Michael HMiller, Michael HDrusano, George L and Drusano, George L
The Journal of clinical investigation, vol. 112, (no. 2), pp. 285, 2003-Jul. | Journal Article
 
Carbapenem-Resistant Strain of Klebsiella oxytoca Harboring Carbapenem-Hydrolyzingβ -Lactamase KPC-2
Yigit, H.Yigit, HesnaQueenan, AMQueenan, AnneRasheed, JKRasheed, J.Biddle, JWBiddle, JamesDomenech-Sanchez, AntonioDomenech-Sanchez, A.Alberti, SebastianAlberti, S.Bush, KarenBush, K.Tenover, Fred and Tenover, Fred
Antimicrobial Agents and Chemotherapy, vol. 47, (no. 12), pp. 3889, 20031201. | Journal Article
 
Cross-resistance, relatedness and allele analysis of fluoroquinolone-resistant US clinical isolates of Streptococcus pneumoniae (1998-2000)
Davies, Todd AGoldschmidt, RaulPfleger, SharonLoeloff, MikeBush, KarenSahm, Daniel F and Evangelista, Alan
The Journal of antimicrobial chemotherapy, vol. 52, (no. 2), pp. 175, 2003-Aug. | Journal Article
 
Novel antibacterial agents for the treatment of serious Gram-positive infections
Abbanat, DarrenMacielag, Mark and Bush, Karen
Expert Opinion on Investigational Drugs, vol. 12, (no. 3), pp. 399, 2003-00-00. | Journal Article
2002
CAU-1, a Subclass B3 Metallo-β-Lactamase of Low Substrate Affinity Encoded by an Ortholog Present in the Caulobacter crescentus Chromosome
Docquier, Jean-DenisDocquier, J.Pantanella, FabrizioPantanella, F.Giuliani, FrancescoGiuliani, F.Thaller, MariaThaller, MCAmicosante, GianfrancoAmicosante, G.Galleni, M.Galleni, MorenoFrere, J.Frère, Jean-MarieBush, KarenBush, K.Rossolini, Gian and Rossolini, Gian M
Antimicrobial Agents and Chemotherapy, vol. 46, (no. 6), pp. 1830, 20020601. | Journal Article
 
ChemInform Abstract: Novel Piperidinyloxy Oxazolidinone Antibacterial Agents. Diversification of the N-Substituent
Weidner-Wells, Michele ABoggs, Christine MFoleno, Barbara DMelton, JohnBush, KarenGoldschmidt, Raul M and Hlasta, Dennis J
ChemInform, vol. 33, (no. 37), pp. no, 2002-09-17. | Journal Article
 
Molecular Correlation for the Treatment Outcomes in Bloodstream Infections Caused by Escherichia coli and Klebsiella pneumoniae with Reduced Susceptibility to Ceftazidime
Wong-Beringer, AnnieHindler, JanetLoeloff, MichaelQueenan, AnneLee, NancyPegues, DavidQuinn, John and Bush, Karen
Clinical Infectious Diseases, vol. 34, (no. 2), pp. 146, 20020115. | Journal Article
 
Novel piperidinyloxy oxazolidinone antibacterial agents. Diversification of the N-Substituent
Weidner-Wells, Michele ABoggs, Christine MFoleno, Barbara DMelton, JohnBush, KarenGoldschmidt, Raul M and Hlasta, Dennis J
Bioorganic & Medicinal Chemistry, vol. 10, (no. 7), pp. 2351, July 2002. | Journal Article
 
Prevalence of Single Mutations in Topoisomerase Type II Genes among Levofloxacin-Susceptible Clinical Strains of Streptococcus pneumoniae Isolated in the United States in 1992 to 1996 and 1999 to 2000
Davies, ToddEvangelista, AlanPfleger, SharonBush, KarenSahm, Daniel and Goldschmidt, Raul
Antimicrobial Agents and Chemotherapy, vol. 46, (no. 1), pp. 124, 20020101. | Journal Article