Our current research focuses on mechanisms that connect lipid metabolism disorder to the systemic inflammation that leads to multiple forms of pathogenic phenotypes in multiple organs.
Lysosomal acid lipase (LAL) hydrolyzes cholesteryl esters and triglycerides to generate free fatty acid and cholesterol in the lysosomes of various cells.
Research
- Lipid metabolism controls tissue inflammation
- Direct stimulation of MDSCs on tumor proliferation
- Establishment of MDSCs-like cell lines
- Establishment of inflammation-induced tumor animal models
- Lung cancer biomarker identification
