The Sharma Lab utilized human stem cells to develop different neuronal subtypes and have a patented pressure model for studying various diseases including glaucoma and eye defects in astronauts.
Her research focuses on understanding intraocular and intracranial pressure associated pathogenesis in glaucoma and Spaceflight Associated Neuro-ocular Syndrome, generation of patient specific neuronal cells, disease modeling of central nervous system diseases, and neuroprotection/regeneration therapeutics.
My research program entails focusing on intraocular and intracranial pressure associated pathogenesis, generation of patient specific neuronal cells, disease modeling of central nervous system diseases, and neuroprotection/regeneration therapeutics. Currently I am developing a range of new glaucoma therapeutics for neuroprotection and pharmacological manipulations of degenerative pathways in glaucoma. Our current studies will identify pathways or molecules that can best be treated with drugs that are beyond intraocular pressure suppression and instead focus on survival of retinal ganglion cells.
