1. The role of homeodomain transcription factors, basic helix-loop-helix transcription factors, and PPAR-gamma during the development of islets and the pathogenesis of islet dysfunction in type 1 and type 2 diabetes,
  2. The interrelationships between chromatin structure and gene transcription in the mature islet, and
  3. The role of post-transcriptional mechanisms in cytokine-mediated islet dysfunction.

Diabetes, islet biology, insulin action, islet inflammation, islet autoimmunity, diabetes biomarkers, B cell development, obesity, insulin resistance

Endocrinology, Pediatrics
MD, University of Chicago, 1993
PhD, University of Chicago, 1991
BA, University of Chicago, 1986