267 Publications (Page 5 of 11)
2010
Systemic Delivery of an Oncolytic Adenovirus Expressing Soluble Transforming Growth Factor-β Receptor II–Fc Fusion Protein Can Inhibit Breast Cancer Bone Metastasis in a Mouse ModelHu, Zebin⋅Zhang, Zhenwei⋅Guise, Theresa and Seth, PremHuman gene therapy, vol. 21, (no. 11), pp. 1629, 2010-Nov.
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Tgf-Beta pathway as a therapeutic target in bone metastases.Juárez, Patricia and Guise, Theresa ACurrent pharmaceutical design, vol. 16, (no. 11), pp. 1301-1312, 2010.
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TGF-β Pathway as a Therapeutic Target in Bone MetastasesJuarez, Patricia and Guise, TheresaCurrent Pharmaceutical Design, vol. 16, (no. 11), pp. 1312, 2010-April.
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Understanding and optimizing bone health in breast cancer.Guise, Theresa A⋅Brufsky, Adam and Coleman, Robert ECurrent medical research and opinion, vol. 26 Suppl 3, pp. 3-20, 2010/Dec.
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Breaking down bone: new insight into site-specific mechanisms of breast cancer osteolysis mediated by metalloproteinases.Guise, Theresa AGenes & development, vol. 23, (no. 18), pp. 2117-23, 2009/Sep/15.
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Cancer treatment-related bone diseaseBrown, Sue A and Guise, Theresa ACritical reviews in eukaryotic gene expression, vol. 19, (no. 1), pp. 60, 2009-00-00.
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Cancer treatment-related bone disease.Brown, Sue A and Guise, Theresa ACritical reviews in eukaryotic gene expression, vol. 19, (no. 1), pp. 47-60, 2009.
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Cancer Treatment-Related Bone DiseaseBrown, Sue A and Guise, Theresa ACritical Reviews™ in Eukaryotic Gene Expression, vol. 19, (no. 1), pp. 60, 2009-00-00.
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Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment.Dunn, Lauren K⋅Mohammad, Khalid S⋅Fournier, Pierrick G⋅McKenna, C R⋅Davis, Holly W⋅Niewolna, Maria⋅Peng, Xiang H⋅Chirgwin, John C and Guise, Theresa APloS one, vol. 4, (no. 9), pp. e6896, 2009.
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Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone MicroenvironmentDunn, Lauren⋅Mohammad, Khalid⋅Fournier, Pierrick⋅Davis, Holly⋅Niewolna, Maria⋅Hong, Xiang⋅Chirgwin, John and Guise, TheresaPLoS One, vol. 4, (no. 9), Sep 2009.
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Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone.Mohammad, Khalid S⋅Chen, Carol G⋅Balooch, Guive⋅Stebbins, Elizabeth⋅McKenna, C R⋅Davis, Holly⋅Niewolna, Maria⋅Peng, Xiang H⋅Nguyen, Daniel H⋅Ionova-Martin, Sophi S⋅Bracey, John W⋅Hogue, William R⋅Wong, Darren H⋅Ritchie, Robert O⋅Suva, Larry J⋅Derynck, Rik⋅Guise, Theresa A and Alliston, TamaraPLoS ONE, vol. 4, (no. 4), pp. e5275, 2009.
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Pharmacologic Inhibition of the TGF-β Type I Receptor Kinase Has Anabolic and Anti-Catabolic Effects on BoneMohammad, K.S.⋅Mohammad, Khalid⋅Mohammad, K.S.⋅Chen, C.G.⋅Chen, C.G.⋅Chen, Carol⋅Balooch, G.⋅Balooch, G.⋅Balooch, Guive⋅Stebbins, E.⋅Stebbins, Elizabeth⋅Stebbins, E.⋅McKenna, C.R.⋅McKenna, C.R.⋅McKenna, C.R.⋅McKenna, C.R.⋅McKenna, C.R.⋅McKenna, C.R.⋅McKenna, C.R.⋅McKenna, C.R.⋅McKenna, C.R.⋅McKenna, C.R.⋅McKenna, C.R.⋅Davis, H.⋅Davis, H.⋅Davis, Holly⋅Niewolna, Maria⋅Niewolna, M.⋅Niewolna, M.⋅Peng, X.H.⋅Hong, Xiang⋅Peng, X.H.⋅Peng, X.H.⋅Peng, X.H.⋅Peng, X.H.⋅Peng, X.H.⋅Peng, X.H.⋅Peng, X.H.⋅Peng, X.H.⋅Peng, X.H.⋅Peng, X.H.⋅Nguyen, Daniel⋅Nguyen, D.H.N.⋅Nguyen, D.H.N.⋅Ionova-Martin, S.S.⋅Ionova-Martin, S.S.⋅Ionova-Martin, Sophi⋅Bracey, J.W.⋅Bracey, John⋅Bracey, J.W.⋅Hogue, William⋅Hogue, W.R.⋅Hogue, W.R.⋅Wong, D.H.⋅Wong, Darren⋅Wong, D.H.⋅Ritchie, R.O.⋅Ritchie, R.O.⋅Ritchie, Robert⋅Suva, L.J.⋅Suva, Larry⋅Suva, L.J.⋅Derynck, Rik⋅Derynck, R.⋅Derynck, R.⋅Guise, T.A.⋅Guise, T.A.⋅Guise, Theresa⋅Alliston, T.⋅Alliston, T. and Alliston, TamaraPLoS One, vol. 4, (no. 4), Apr 2009.
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RANKL: Targeting bone and cancer to treat skeletal complications of malignancyCrook, Margaret K and Guise, Theresa AIBMS BoneKEy, vol. 6, (no. 9), pp. 338, 2009-09-00.
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The critical role of the bone microenvironment in cancer metastases.Casimiro, Sandra⋅Casimiro, Sandra⋅Guise, Theresa A⋅Guise, Theresa A⋅Chirgwin, John and Chirgwin, JohnMolecular and cellular endocrinology, vol. 310, (no. 1-2), pp. 71-81, 2009/Oct/30.
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2008
Advancing treatment for metastatic bone cancer: consensus recommendations from the Second Cambridge Conference.Coleman, Robert E⋅Coleman, R.E.⋅Guise, Theresa A⋅Guise, T.A.⋅Lipton, A.⋅Lipton, Allan⋅Roodman, G D⋅Roodman, G.D.⋅Berenson, James R⋅Berenson, J.R.⋅Body, J.-J.⋅Body, Jean-Jacques⋅Boyce, B.F.⋅Boyce, Brendan F⋅Calvi, Laura M⋅Calvi, L.M.⋅Hadji, P.⋅Hadji, Peyman⋅McCloskey, Eugene V⋅McCloskey, E.V.⋅Saad, Fred⋅Saad, F.⋅Smith, M.R.⋅Smith, Matthew R⋅Suva, L.J.⋅Suva, Larry J⋅Taichman, R.S.⋅Taichman, Russell S⋅Vessella, R.L.⋅Vessella, Robert L⋅Weilbaecher, K.N. and Weilbaecher, Katherine NClinical cancer research : an official journal of the American Association for Cancer Research, vol. 14, (no. 20), pp. 6387-95, 2008/Oct/15.
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Antitumor effects of bisphosphonates: promising preclinical evidence.Guise, Theresa ACancer treatment reviews, vol. 34 Suppl 1, pp. S19-24, 2008.
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Molecular mechanisms and treatment of bone metastasisClines, Gregory and Guise, TheresaExpert Reviews in Molecular Medicine, vol. 10, (no. 7), pp. e7, Mar 2008.
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OC12. Specific inhibition of the VEGF homolog placental growth factor is protective against osteolytic bone metastasis in miceCoenegrachts, Lieve⋅Maes, Christa⋅Torrekens, Sophie⋅Van Looveren, Riet⋅Mazzone, Massimiliano⋅Guise, Theresa⋅Bouillon, Roger⋅Carmeliet, Peter and Carmeliet, GeertCancer Treatment Reviews, vol. 34, pp. 11, 2008.
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P16. Hypoxia and breast cancer bone metastasis: HIF-1α enhances TGF-β signaling and expression of prometastatic factors CXCR4 and VEGFKingsley, Lauren⋅Kingsley, Lauren⋅Fournier, Pierrick⋅Fournier, Pierrick⋅Chirgwin, John⋅Chirgwin, John⋅Guise, Theresa and Guise, TheresaCancer Treatment Reviews, vol. 34, pp. 18, 2008.
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P32. Transforming growth factor-β (TGF-β) promotes prostate cancer bone metastases: Increased expression of pro-osteolytic genes and of PMEPA1, a new TGF-β signalling regulatorFournier, Pierrick⋅Fournier, Pierrick⋅Clines, Gregory⋅Clines, Gregory⋅Chirgwin, John⋅Chirgwin, John⋅Guise, Theresa and Guise, TheresaCancer Treatment Reviews, vol. 34, pp. 25, 2008.
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P38. RANKL plays a role in migration and invasion of the bone-seeking cell line MDA-MB-231-BO2 and regulates MMP1 and MMP9 expressionCasimiro, Sandra⋅Alho, Irina⋅Fernandes, Afonso⋅Lipton, Allan⋅Guise, Theresa and Costa, LuisCancer Treatment Reviews, vol. 34, pp. 28, 2008.
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P48. Transforming growth factor β receptor I kinase inhibitor and bisphosphonates are additive to reduce breast cancer bone metastasesMohammad, Khalid⋅Mohammad, Khalid⋅Stebbins, Elizabeth⋅Stebbins, Elizabeth⋅Kingsley, Lauren⋅Kingsley, Lauren⋅Fournier, Pierrick⋅Fournier, Pierrick⋅Niewolna, Maria⋅Niewolna, Maria⋅McKenna, Christopher⋅McKenna, Christopher⋅Peng, Xianhong⋅Peng, Xianhong⋅Higgins, Linda⋅Higgins, Linda⋅Wong, Darren⋅Wong, Darren⋅Guise, Theresa and Guise, TheresaCancer Treatment Reviews, vol. 34, pp. 38, 2008.
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