30 Publications (Page 1 of 2)
2022
Diagnostic Evidence GAuge of Single cells (DEGAS): a flexible deep transfer learning framework for prioritizing cells in relation to disease
Johnson, Travis S⋅Johnson, Travis S⋅Johnson, Travis S⋅Yu, Christina Y⋅Yu, Christina Y⋅Yu, Christina Y⋅Huang, Zhi⋅Huang, Zhi⋅Huang, Zhi⋅Xu, Siwen⋅Xu, Siwen⋅Xu, Siwen⋅Wang, Tongxin⋅Wang, Tongxin⋅Wang, Tongxin⋅Dong, Chuanpeng⋅Dong, Chuanpeng⋅Dong, Chuanpeng⋅Shao, Wei⋅Shao, Wei⋅Shao, Wei⋅Huang, Xiaoqing⋅Huang, Xiaoqing⋅Huang, Xiaoqing⋅Wang, Yijie⋅Wang, Yijie⋅Wang, Yijie⋅Bartlett, Christopher⋅Bartlett, Christopher⋅Bartlett, Christopher⋅Zhang, Yan⋅Zhang, Yan⋅Zhang, Yan⋅Walker, Brian A⋅Walker, Brian A⋅Walker, Brian A⋅Liu, Yunlong⋅Liu, Yunlong⋅Liu, Yunlong⋅Huang, Kun⋅Huang, Kun⋅Huang, Kun⋅Zhang, Jie⋅Zhang, Jie and Zhang, Jie
Genome Medicine, vol. 14, pp. 1-23, 2022. | Journal Article
 
Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers
Mikulasova, Aneta⋅Kent, Daniel⋅Trevisan-Herraz, Marco⋅Karataraki, Nefeli⋅Fung, Kent T⋅Ashby, Cody⋅Cieslak, Agata⋅Yaccoby, Shmuel⋅van Rhee, Frits⋅Zangari, Maurizio⋅Thanendrarajan, Sharmilan⋅Schinke, Carolina⋅Morgan, Gareth J⋅Asnafi, Vahid⋅Spicuglia, Salvatore⋅Brackley, Chris A⋅Corcoran, Anne E⋅Hambleton, Sophie⋅Walker, Brian A⋅Rico, Daniel and Russell, Lisa J
Genome Research, vol. 32, (no. 7), Jul 2022. | Journal Article
 
Improving prognostic assignment in older adults with multiple myeloma using acquired genetic features, clonal hemopoiesis and telomere length
Boyle, Eileen M⋅Williams, Louis⋅Blaney, Patrick⋅Ashby, Cody⋅Bauer, Michael⋅Walker, Brian A⋅⋅Choi, Jinyoung⋅Wang, Yubao⋅Caro, Jessica⋅Stoeckle, James H⋅Kaminetzky, David⋅Braunstein, Marc⋅Benedetto, Bruno⋅Diamond, Benjamin⋅⋅Francesco, Maura⋅⋅Litke, Rachel⋅Fegan, Christopher D⋅⋅Auclair, Daniel⋅Davies, Faith E and Morgan, Gareth J
Leukemia, vol. 36, (no. 1), pp. 221-224, Jan 2022. | Journal Article
 
Plasma cells expression from smouldering myeloma to myeloma reveals the importance of the PRC2 complex, cell cycle progression, and the divergent evolutionary pathways within the different molecular subgroups
Boyle, Eileen M⋅Rosenthal, Adam⋅Ghamlouch, Hussein⋅Wang, Yan⋅Farmer, Phillip⋅Rutherford, Michael⋅Ashby, Cody⋅Bauer, Michael⋅Johnson, Sarah K⋅Wardell, Christopher P⋅Wang, Yubao⋅Hoering, Antje⋅Schinke, Carolina⋅Thanendrarajan, Sharmilan⋅Sharmilan, Thanendrarajan⋅Zangari, Maurizio⋅Barlogie, Bart⋅Dhodapkar, Madhav V⋅Davies, Faith E⋅Morgan, Gareth J⋅van Rhee, Frits and Walker, Brian A
Leukemia, vol. 36, (no. 2), pp. 591-595, Feb 2022. | Journal Article
2021
Chromosomal 1q21 abnormalities in multiple myeloma: a review of translational, clinical research, and therapeutic strategies.
Bisht, Kamlesh⋅Walker, Brian⋅Kumar, Shaji K⋅Spicka, Ivan⋅Moreau, Philippe⋅Martin, Tom⋅Costa, Luciano J⋅Richter, Joshua⋅Fukao, Taro⋅Macé, Sandrine and van de Velde, Helgi
Expert review of hematology, September 23, 2021. | Journal Article
 
Insights into high-risk multiple myeloma from an analysis of the role of PHF19 in cancer
Ghamlouch, Hussein⋅Boyle, Eileen M⋅Blaney, Patrick⋅Wang, Yubao⋅Choi, Jinyoung⋅Williams, Louis⋅Bauer, Michael⋅Auclair, Daniel⋅Benedetto, Bruno⋅Walker, Brian A⋅Davies, Faith E and Morgan, Gareth J
(pp. 1-23). 2021
 
Intron retention-induced neoantigen load correlates with unfavorable prognosis in multiple myeloma
⋅Dong, Chuanpeng⋅Dong, Chuanpeng⋅Cesarano, Annamaria⋅Cesarano, Annamaria⋅Bombaci, Giuseppe⋅Bombaci, Giuseppe⋅Reiter, Jill L⋅Reiter, Jill L⋅Reiter, Jill L⋅Yu, Christina Y⋅Yu, Christina Y⋅Yu, Christina Y⋅Wang, Yue⋅Wang, Yue⋅Wang, Yue⋅Jiang, Zhaoyang⋅Jiang, Zhaoyang⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Zaid, Mohammad A⋅Huang, Kun⋅Huang, Kun⋅Huang, Kun⋅⋅Lu, Xiongbin⋅Lu, Xiongbin⋅Walker, Brian A⋅Walker, Brian A⋅Walker, Brian A⋅Perna, Fabiana⋅⋅Perna, Fabiana⋅Liu, Yunlong⋅Liu, Yunlong and Liu, Yunlong
Oncogene, vol. 40, (no. 42), pp. 6130-6138, Oct 2021. | Journal Article
 
Monitoring treatment response and disease progression in myeloma with circulating cell‐free DNA
Deshpande, Shayu⋅Deshpande, Shayu⋅Tytarenko, Ruslana G⋅Tytarenko, Ruslana G⋅Wang, Yan⋅Wang, Yan⋅Boyle, Eileen M⋅Boyle, Eileen M⋅Ashby, Cody⋅Ashby, Cody⋅Schinke, Carolina D⋅Schinke, Carolina D⋅Thanendrarajan, Sharmilan⋅Thanendrarajan, Sharmilan⋅Zangari, Maurizio⋅Zangari, Maurizio⋅Zhan, Fenghuang⋅Zhan, Fenghuang⋅Davies, Faith E⋅Davies, Faith E⋅Morgan, Gareth J⋅Morgan, Gareth J⋅⋅⋅Walker, Brian A and Walker, Brian A
European Journal of Haematology, vol. 106, (no. 2), pp. 230-240, Feb 2021. | Journal Article
 
The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
Boyle, Eileen M⋅Boyle, Eileen M⋅Boyle, Eileen M⋅Deshpande, Shayu⋅Tytarenko, Ruslana⋅Ashby, Cody⋅Ashby, Cody⋅Ashby, Cody⋅Wang, Yan⋅Wang, Yan⋅Wang, Yan⋅Bauer, Michael A⋅Bauer, Michael A⋅Bauer, Michael A⋅Johnson, Sarah K⋅Johnson, Sarah K⋅Johnson, Sarah K⋅Wardell, Christopher P⋅Wardell, Christopher P⋅Wardell, Christopher P⋅Sharmilan, Thanendrarajan⋅Thanendrarajan, Sharmilan⋅Zangari, Maurizio⋅Facon, Thierry⋅Dumontet, Charles⋅Dumontet, Charles⋅Dumontet, Charles⋅Barlogie, Bart⋅Arbini, Arnaldo⋅Rustad, Even H⋅Rustad, Even H⋅Rustad, Even H⋅Maura, Francesco⋅Francesco, Maura⋅⋅Landgren, Ola⋅Zhan, Fenghuang⋅van Rhee, Frits⋅Schinke, Carolina⋅Schinke, Carolina⋅Schinke, Carolina⋅Davies, Faith E⋅Davies, Faith E⋅Davies, Faith E⋅Morgan, Gareth J⋅Morgan, Gareth J⋅Morgan, Gareth J⋅Walker, Brian A⋅Walker, Brian A and Walker, Brian A
Nature Communications, vol. 12, (no. 1), 2021. | Journal Article
 
Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities
Oben, Bénedith⋅Oben, Bénedith⋅Froyen, Guy⋅Froyen, Guy⋅⋅⋅Maclachlan, Kylee H⋅Maclachlan, Kylee H⋅Maclachlan, Kylee H⋅Maclachlan, Kylee H⋅Leongamornlert, Daniel⋅Leongamornlert, Daniel⋅Leongamornlert, Daniel⋅Leongamornlert, Daniel⋅⋅⋅Abascal, Federico⋅Abascal, Federico⋅Zheng-Lin, Binbin⋅Zheng-Lin, Binbin⋅Zheng-Lin, Binbin⋅Zheng-Lin, Binbin⋅Yellapantula, Venkata⋅Yellapantula, Venkata⋅Derkach, Andriy⋅Derkach, Andriy⋅Geerdens, Ellen⋅Geerdens, Ellen⋅Diamond, Benjamin T⋅Diamond, Benjamin T⋅Diamond, Benjamin T⋅Diamond, Benjamin T⋅⋅⋅Arijs, Ingrid⋅Arijs, Ingrid⋅Maes, Brigitte⋅Maes, Brigitte⋅Maes, Brigitte⋅Maes, Brigitte⋅Vanhees, Kimberly⋅Vanhees, Kimberly⋅Vanhees, Kimberly⋅Vanhees, Kimberly⋅⋅Hultcrantz, Malin⋅⋅Hultcrantz, Malin⋅Manasanch, Elisabet E⋅Manasanch, Elisabet E⋅Manasanch, Elisabet E⋅Manasanch, Elisabet E⋅Kazandjian, Dickran⋅Kazandjian, Dickran⋅Lesokhin, Alexander⋅Lesokhin, Alexander⋅Dogan, Ahmet⋅⋅⋅Dogan, Ahmet⋅Zhang, Yanming⋅Zhang, Yanming⋅Zhang, Yanming⋅Zhang, Yanming⋅Mikulasova, Aneta⋅Mikulasova, Aneta⋅Walker, Brian⋅Walker, Brian⋅Walker, Brian⋅Walker, Brian⋅Morgan, Gareth⋅Morgan, Gareth⋅Morgan, Gareth⋅Morgan, Gareth⋅Campbell, Peter J⋅Campbell, Peter J⋅Campbell, Peter J⋅Campbell, Peter J⋅Landgren, Ola⋅⋅Landgren, Ola⋅⋅Rummens, Jean-Luc⋅Rummens, Jean-Luc⋅Bolli, Niccolò⋅Bolli, Niccolò⋅Maura, Francesco⋅Maura, Francesco⋅Francesco, Maura and Francesco, Maura
Nature Communications, vol. 12, (no. 1), 2021. | Journal Article
2020
Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns
Schinke, Carolina⋅Boyle, Eileen M⋅Ashby, Cody⋅Wang, Yan⋅Wardell, Christopher⋅Ryan, Katie⋅Sharmilan, Thanendrarajan⋅Mohan, Meera⋅Khan, Maliha⋅Choudhury, Samrat R⋅Davies, Faith⋅Morgan, Gareth and Walker, Brian A
Blood Cancer Journal, vol. 10, (no. 6), Jun 2020. | Journal Article
 
Inactivating NF1 Mutations Are Enriched in Advanced Breast Cancer and Contribute to Endocrine Therapy Resistance
Pearson, Alex⋅Proszek, Paula⋅Pascual, Javier⋅Fribbens, Charlotte⋅Shamsher, Monee K⋅Kingston, Belinda⋅O'Leary, Ben⋅Herrera-Abreu, Maria T⋅Cutts, Rosalind J⋅Garcia-Murillas, Isaac⋅Bye, Hannah⋅Walker, Brian A⋅Gonzalez De Castro, David⋅Yuan, Lina⋅Jamal, Sabri⋅Hubank, Mike⋅Lopez-Knowles, Elena⋅Schuster, Eugene F⋅Dowsett, Mitch⋅Osin, Peter⋅Nerurkar, Ashutosh⋅Parton, Marina⋅Okines, Alicia F C⋅Johnston, Stephen R D⋅Ring, Alistair and Turner, Nicholas C
Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 26, (no. 3), pp. 622, 2020-Feb-01. | Journal Article
 
TarPan: an easily adaptable targeted sequencing panel viewer for research and clinical use
Ashby, Cody⋅Rutherford, Michael⋅Bauer, Michael A⋅Peterson, Erich A⋅Wang, Yan⋅Boyle, Eileen M⋅Wardell, Christopher P and Walker, Brian A
BMC Bioinformatics , vol. 21, pp. 1-12, 2020. | Journal Article
 
The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma
Ashby, Cody⋅Tytarenko, Ruslana⋅Bauer, Michael⋅Wang, Yan⋅Deshpande, Shayu⋅Den, Judith⋅Schinke, Carolina⋅Zangari, Maurizio⋅Thanendrarajan, Sharmilan⋅Davies, Faith E⋅Morgan, Gareth J and Walker, Brian A
Journal of Hematology & Oncology, vol. 13, pp. 1-15, 2020. | Journal Article
2019
A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
Walker, Brian A⋅Mavrommatis, Konstantinos⋅Wardell, Christopher P⋅Ashby, T Cody⋅Bauer, Michael⋅Davies, Faith⋅Rosenthal, Adam⋅Wang, Hongwei⋅Qu, Pingping⋅Hoering, Antje⋅Samur, Mehmet⋅Towfic, Fadi⋅Ortiz, Maria⋅Flynt, Erin⋅Yu, Zhinuan⋅Yang, Zhihong⋅Rozelle, Dan⋅Obenauer, John⋅Trotter, Matthew⋅Auclair, Daniel⋅Keats, Jonathan⋅Bolli, Niccolo⋅Fulciniti, Mariateresa⋅Szalat, Raphael⋅Moreau, Phillipe⋅Durie, Brian⋅Stewart, A Keith⋅Goldschmidt, Hartmut⋅Raab, Marc S⋅Einsele, Hermann⋅Sonneveld, Pieter⋅San Miguel, Jesus⋅Lonial, Sagar⋅Jackson, Graham H⋅Anderson, Kenneth C⋅Avet-Loiseau, Herve⋅Munshi, Nikhil⋅Thakurta, Anjan and Morgan, Gareth
Leukemia, vol. 33, (no. 1), pp. 170, 2019-Jan. | Journal Article
 
An acquired high-risk chromosome instability phenotype in multiple myeloma: Jumping 1q Syndrome
Sawyer, Jeffrey R⋅Tian, Erming⋅Walker, Brian A⋅Wardell, Christopher⋅Lukacs, Janet L⋅Sammartino, Gael⋅Bailey, Clyde⋅Schinke, Carolina D⋅Thanendrarajan, Sharmilan⋅Davies, Faith E⋅Morgan, Gareth J⋅Barlogie, Bart⋅Zangari, Maurizio and van Rhee, Frits
Blood cancer journal, vol. 9, (no. 8), pp. 12, 2019-08-09. | Journal Article
 
A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations
George, Sally L⋅Izquierdo, Elisa⋅Campbell, James⋅Koutroumanidou, Eleni⋅Proszek, Paula⋅Jamal, Sabri⋅Hughes, Deborah⋅Yuan, Lina⋅Marshall, Lynley V⋅Carceller, Fernando⋅Chisholm, Julia C⋅Vaidya, Sucheta⋅Mandeville, Henry⋅Angelini, Paola⋅Wasti, Ajla⋅Bexelius, Tomas⋅Thway, Khin⋅Gatz, Susanne A⋅Clarke, Matthew⋅Al-Lazikani, Bissan⋅Barone, Giuseppe⋅Anderson, John⋅Tweddle, Deborah A⋅Gonzalez, David⋅Walker, Brian A⋅Barton, Jack⋅Depani, Sarita⋅Eze, Jessica⋅Ahmed, Saira W⋅Moreno, Lucas⋅Pearson, Andrew⋅Shipley, Janet⋅Jones, Chris⋅Hargrave, Darren⋅Jacques, Thomas S⋅Hubank, Michael and Chesler, Louis
European Journal of Cancer, vol. 121, pp. 235, November 2019. | Journal Article
 
Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients
Jones, John R⋅Weinhold, Niels⋅Ashby, Cody⋅Walker, Brian A⋅Wardell, Chris⋅Pawlyn, Charlotte⋅Rasche, Leo⋅Melchor, Lorenzo⋅Cairns, David A⋅Gregory, Walter M⋅Johnson, David⋅Begum, Dil B⋅Ellis, Sidra⋅Sherborne, Amy L⋅Cook, Gordon⋅Kaiser, Martin F⋅Drayson, Mark T⋅Owen, Roger G⋅Jackson, Graham H⋅Davies, Faith E⋅Greaves, Mel and Morgan, Gareth J
Haematologica, vol. 104, (no. 7), pp. 1450, 2019-07-00. | Journal Article
 
Daratumumab and dexamethasone is safe and effective for triple refractory myeloma patients: final results of the IFM 2014‐04 (Etoile du Nord) trial
Boyle, Eileen M⋅Leleu, Xavier⋅Petillon, Marie‐Odile⋅Karlin, Lionel⋅Doyen, Chantal⋅Demarquette, Hélène⋅Royer, Bruno⋅Macro, Margaret⋅Moreau, Philippe⋅Fostier, Karel⋅Marie‐Lorraine, Chretien⋅Zarnitsky, Charles⋅Perrot, Aurore⋅Herbaux, Charles⋅Poulain, Stephanie⋅Manier, Salomon⋅Beauvais, David⋅Walker, Brian A⋅Wardell, Christopher P⋅Vincent, Laure⋅Frenzel, Laurent⋅Caillon, Hélène⋅Susanna, Schraen⋅Dejoie, Thomas⋅Avet‐Loiseau, Hervé⋅Mohty, Mohamad⋅Facon, Thierry⋅Arnulf, Bertrand⋅Dib, Mamoun⋅Brechignac‐Bureau, Sabine⋅Godmer, Pascal⋅Tempescul, Adrian⋅Fohrer, Cecile⋅Benboubker, Lotfi⋅Voillat, Laurent⋅Malfuson, Jean Valère⋅Mariette, Clara⋅Tiab, Mourad⋅Rigaudeau, Sophie⋅Jaccard, Arnaud⋅Stoppa, Anne‐Marie⋅Eisenmann, Jean‐Claude⋅Rodon, Philippe⋅Kolb, Brigitte⋅Decaux, Olivier⋅Onraed, Brigitte⋅Attal, Michel and Hulin, Cyrille
British Journal of Haematology, vol. 187, (no. 3), pp. 327, November 2019. | Journal Article
 
Poor overall survival in hyperhaploid multiple myeloma is defined by double-hit bi-allelic inactivation of TP53
Ashby, Cody⋅Tytarenko, Ruslana G⋅Wang, Yan⋅Weinhold, Niels⋅Johnson, Sarah K⋅Bauer, Michael⋅Wardell, Christopher P⋅Schinke, Carolina⋅Thanendrarajan, Sharmilan⋅Zangari, Mauricio⋅van Rhee, Frits⋅Davies, Faith E⋅Sawyer, Jeffrey R⋅Morgan, Gareth J and Walker, Brian A
Oncotarget, vol. 10, (no. 7), pp. 737, 2019-Jan-22. | Journal Article
2018
An Acquired High-Risk Chromosome Instability Phenotype in Multiple Myeloma: Jumping 1q Syndrome
Sawyer, Jeffery R⋅Tian, Erming⋅Walker, Brian A⋅Wardell, Christopher P⋅Epstein, Joshua⋅Lukacs, Janet L⋅Sammartino, Gael M⋅Bailey, Clyde⋅Schinke, Carolina D⋅Thanendrarajan, Sharmilan⋅Zangari, Maurizio⋅Davies, Faith E⋅van Rhee, Frits and Morgan, Gareth
Blood, vol. 132, (no. Supplement 1), pp. 4489, 2018-11-29. | Journal Article
 
Combination of Flow Cytometry and Functional Imaging for Monitoring of Residual Disease in Myeloma
Rasche, Leo⋅Alapat, Daisy⋅Kumar, Manoj⋅Gershner, Grant⋅McDonald, James E⋅Wardell, Christopher P⋅Roy Choudhury, Samrat⋅Van Hemert, Rudy L⋅Epstein, Joshua⋅Williams, Amy F⋅Thanendrarajan, Sharmilan⋅Schinke, Carolina D⋅Bauer, Michael A⋅Ashby, Cody⋅Tytarenko, Ruslana G⋅van Rhee, Frits⋅Walker, Brian A⋅Zangari, Maurizio⋅Barlogie, Bart⋅Davies, Faith E⋅Morgan, Gareth and Weinhold, Niels
Blood, vol. 132, (no. Supplement 1), pp. 3185, 2018-11-29. | Journal Article
 
Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
Walker, Brian A⋅Mavrommatis, Konstantinos⋅Wardell, Christopher P⋅Ashby, T Cody⋅Bauer, Michael⋅Davies, Faith E⋅Rosenthal, Adam⋅Wang, Hongwei⋅Qu, Pingping⋅Hoering, Antje⋅Samur, Mehmet⋅Towfic, Fadi⋅Ortiz, Maria⋅Flynt, Erin⋅Yu, Zhinuan⋅Yang, Zhihong⋅Rozelle, Dan⋅Obenauer, John⋅Trotter, Matthew⋅Auclair, Daniel⋅Keats, Jonathan⋅Bolli, Niccolo⋅Fulciniti, Mariateresa⋅Szalat, Raphael⋅Moreau, Philippe⋅Durie, Brian⋅Stewart, A Keith⋅Goldschmidt, Hartmut⋅Raab, Marc S⋅Einsele, Hermann⋅Sonneveld, Pieter⋅San Miguel, Jesus⋅Lonial, Sagar⋅Jackson, Graham H⋅Anderson, Kenneth C⋅Avet-Loiseau, Herve⋅Munshi, Nikhil⋅Thakurta, Anjan and Morgan, Gareth J
Blood, vol. 132, (no. 6), pp. 597, 2018-08-09. | Journal Article
 
MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma
Ya-Wei, Qiang⋅Ye, Shiqiao⋅Huang, Yuhua⋅Chen, Yu⋅Epstein, Joshua⋅Walker, Brian A⋅Morgan, Gareth J and Davies, Faith E
BMC Cancer, vol. 18, 2018. | Journal Article
 
Poor Overall Survival in Hyperhaploid Multiple Myeloma Is Defined By Double-Hit Bi-Allelic Inactivation of TP53
Ashby, Cody⋅Wang, Yan⋅Tytarenko, Ruslana G⋅Schinke, Carolina D⋅Thanendrarajan, Sharmilan⋅Zangari, Maurizio⋅van Rhee, Frits⋅Davies, Faith E⋅Sawyer, Jeffery R⋅Morgan, Gareth and Walker, Brian A
Blood, vol. 132, (no. Supplement 1), pp. 4441, 2018-11-29. | Journal Article