61 Publications (Page 1 of 3)
2020
H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes
Kwon, MinjungPark, KihyunHyun, KwangbeomLee, Jeong-HeonZhou, LinjiaoCho, Young-WookGe, KaiSkalnik, David GMuir, Tom W and Kim, Jaehoon
Nucleic acids research, 2020-May-04. | Journal Article
2018
Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2.
Higgs, Martin RSato, KoichiReynolds, John JBegum, ShabanaBayley, RachelGoula, AmaliaVernet, AudreyPaquin, Karissa LSkalnik, David GKobayashi, WataruTakata, MinoruHowlett, Niall GKurumizaka, HitoshiKimura, Hiroshi and Stewart, Grant S
Molecular cell, June 7, 2018. | Journal Article
 
Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a
Kim, Kun-YongKun-Yong, KimKun-Yong, KimTanaka, YoshiakiTanaka, YoshiakiTanaka, YoshiakiSu, JuanSu, JuanSu, JuanCakir, BilalCakir, BilalCakir, BilalXiang, YangfeiPatterson, BenjaminPatterson, BenjaminPatterson, BenjaminDing, JunjunDing, JunjunDing, JunjunJung, Yong-WookJi-Hyun, KimJi-Hyun, KimKim, Ji-HyunHysolli, ErionaHysolli, ErionaHysolli, ErionaLee, HaelimLee, HaelimLee, HaelimDajani, RanaDajani, RanaDajani, RanaKim, JonghwanKim, JonghwanKim, JonghwanZhong, MeiZhong, MeiZhong, MeiLee, Jeong-HeonJeong-Heon, LeeJeong-Heon, LeeSkalnik, DavidSkalnik, DavidSkalnik, DavidLim, Jeong MookLim, Jeong MLim, Jeong MSullivan, Gareth JSullivan, Gareth JSullivan, Gareth JWang, JianlongWang, JianlongWang, JianlongPark, In-HyunPark, In-Hyun and Park, In-Hyun
Nature communications, vol. 9, (no. 1), pp. 13, 2018-07-03. | Journal Article
2016
Efficient differentiation of murine embryonic stem cells requires the binding of CXXC finger protein 1 to DNA or methylated histone H3-Lys4
Mahadevan, Jyothi and Skalnik, David G
Gene, vol. 594, (no. 1), pp. 9, 2016-12-05. | Journal Article
 
H3K4 Methyltransferase Set1a Is A Key Oct4 Coactivator Essential for Generation of Oct4 Positive Inner Cell Mass
Fang, LanZhang, JunZhang, HuiYang, XiaoqinJin, XuelingZhang, LingSkalnik, David GJin, YingZhang, YongHuang, XingxuLi, Jiwen and Wong, Jiemin
STEM CELLS, vol. 34, (no. 3), pp. 580, March 2016. | Journal Article
 
Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes
Alicea-Velázquez, Nilda LAlicea-Velázquez, Nilda LShinsky, Stephen AShinsky, Stephen ALoh, Daniel MLoh, Daniel MLee, Jeong-HeonLee, Jeong-HeonSkalnik, David GSkalnik, David GCosgrove, Michael S and Cosgrove, Michael S
The Journal of biological chemistry, vol. 291, (no. 43), pp. 22372, 2016-Oct-21. | Journal Article
2014
The Epigenetic Regulator CXXC Finger Protein 1 is Essential for Murine Hematopoiesis
Chun, Kristin TChun, Kristin TLi, BinghuiLi, BinghuiDobrota, ErikaDobrota, ErikaTate, CourtneyTate, CourtneyLee, Jeong-HeonLee, Jeong-HeonKhan, ShehnazKhan, ShehnazHaneline, LauraHaneline, LauraHogenEsch, HarmHogenEsch, HarmSkalnik, David G and Skalnik, David G
PloS one, vol. 9, (no. 12), pp. e113745, 2014-00-00. | Journal Article
2012
Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells
Clouaire, ThomasWebb, ShaunSkene, PeteIllingworth, RobertKerr, AlastairAndrews, RobertLee, Jeong-HeonSkalnik, David and Bird, Adrian
Genes & development, vol. 26, (no. 15), pp. 1728, 2012-Aug-01. | Journal Article
 
Dynamic Loss of H2B Ubiquitylation without Corresponding Changes in H3K4 Trimethylation during Myogenic Differentiation
Vethantham, VasupradhaVethantham, VasupradhaYang, YanYang, YanBowman, ChristopherBowman, ChristopherAsp, PatrikAsp, PatrikLee, Jeong-HeonLee, Jeong-HeonSkalnik, David GSkalnik, DavidDynlacht, Brian and Dynlacht, Brian D
Molecular and Cellular Biology, vol. 32, (no. 6), pp. 1055, 20120315. | Journal Article
 
Rbm15-Mkl1 Interacts with the Setd1b Histone H3-Lys4 Methyltransferase via a SPOC Domain That Is Required for Cytokine-Independent Proliferation
Lee, Jeong-Heon and Skalnik, David G
PloS one, vol. 7, (no. 8), pp. e42965, 2012-00-00. | Journal Article
 
Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases
Dharmarajan, VenkatasubramanianDharmarajan, VenkatasubramanianLee, Jeong-HeonLee, Jeong-HeonPatel, AnamikaPatel, AnamikaSkalnik, David GSkalnik, David GCosgrove, Michael S and Cosgrove, Michael S
The Journal of biological chemistry, vol. 287, (no. 33), pp. 27289, 2012-Aug-10. | Journal Article
2011
The Human Immunodeficiency Virus Protease Inhibitor Ritonavir Inhibits Lung Cancer Cells, in Part, by Inhibition of Survivin
Srirangam, AnjaiahSrirangam, AnjaiahSrirangam, AnjaiahSrirangam, AnjaiahMilani, MonicaMilani, MonicaMilani, MonicaMilani, MonicaMitra, RanjanaMitra, RanjanaMitra, RanjanaMitra, RanjanaGuo, ZhijunGuo, ZhijunGuo, ZhijunGuo, ZhijunRodriguez, MariangellysRodriguez, MariangellysRodriguez, MariangellysRodriguez, MariangellysKathuria, HiteshKathuria, HiteshKathuria, HiteshKathuria, HiteshFukuda, SeijiFukuda, SeijiFukuda, SeijiFukuda, SeijiRizzardi, AnthonyRizzardi, AnthonyRizzardi, AnthonyRizzardi, AnthonySchmechel, StephenSchmechel, StephenSchmechel, StephenSchmechel, StephenSkalnik, David GSkalnik, David GSkalnik, David GSkalnik, David GPelus, Louis MPelus, Louis MPelus, Louis MPelus, Louis MPotter, David APotter, David APotter, David A and Potter, David A
Journal of Thoracic Oncology, vol. 6, (no. 4), pp. 670, April 2011. | Journal Article
2010
CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin.
Tate, Courtney MLee, Jeong-Heon and Skalnik, David G
The FEBS journal, vol. 277, (no. 1), pp. 210-23, 2010/Jan. | Journal Article
 
Identification and characterization of a novel human PP1 phosphatase complex.
Lee, Jeong-HeonYou, JinsamDobrota, Erika and Skalnik, David G
The Journal of biological chemistry, vol. 285, (no. 32), pp. 24466-76, 2010/Aug/6. | Journal Article
 
The epigenetic regulator Cfp1
Skalnik, David G
Biomolecular concepts, vol. 1, (no. 5), pp. 334, 2010-12-01. | Journal Article
2009
CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation.
Tate, Courtney MLee, Jeong-Heon and Skalnik, David G
Molecular and cellular biology, vol. 29, (no. 14), pp. 3817-31, 2009/Jul. | Journal Article
 
DNA Methyltransferase Protein Synthesis Is Reduced in CXXC Finger Protein 1-Deficient Embryonic Stem Cells
Butler, JSButler, Jill SPalam, LRPalam, Lakshmi RTate, CMTate, Courtney MSanford, JeremySanford, Jeremy RWek, RonaldWek, Ronald CSkalnik, David G and Skalnik, David G
DNA and Cell Biology, vol. 28, (no. 5), pp. 223-231, 2009. | Journal Article
 
Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity
Tate, Courtney MTate, Courtney MFishel, Melissa LFishel, Melissa LHolleran, Julianne LHolleran, Julianne LEgorin, Merrill JEgorin, Merrill JSkalnik, David G and Skalnik, David G
DNA Repair, vol. 8, (no. 12), pp. 1423, 2009. | Journal Article
 
Identification of a minimal cis-element and cognate trans-factor(s) required for induction of Rac2 gene expression during K562 cell differentiation.
Muthukrishnan, Rajarajeswari and Skalnik, David G
Gene, vol. 440, (no. 1-2), pp. 63-72, 2009/Jul/1. | Journal Article
 
Methyl group acceptance assay for the determination of global DNA methylation levels
Nephew, Kenneth PNephew, KenBalch, CurtBalch, CurtSkalnik, David G and Skalnik, David G
Methods in molecular biology (Clifton, N.J.), vol. 507, pp. 35, 2009-00-00. | Journal Article
2008
CFP1 Interacts with DNMT1 Independently of Association with the Setd1 Histone H3K4 Methyltransferase Complexes
Butler, JSLee, J-H and Skalnik, David G
DNA and Cell Biology, vol. 27, (no. 10), pp. 533-543, 2008. | Journal Article
 
Wdr82 Is a C-Terminal Domain-Binding Protein That Recruits the Setd1A Histone H3-Lys4 Methyltransferase Complex to Transcription Start Sites of Transcribed Human Genes
Lee, Jeong-Heon and Skalnik, David
Molecular and Cellular Biology, vol. 28, (no. 2), pp. 618, 20080115. | Journal Article
2007
CXXC Finger Protein 1 Is Required for Normal Proliferation and Differentiation of the PLB-985 Myeloid Cell Line
Young, SRL and Skalnik, David G
DNA and Cell Biology, vol. 26, (no. 2), pp. 80-90, 2007. | Journal Article
 
Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex.
Lee, Jeong-HeonTate, Courtney MYou, Jin-Sam and Skalnik, David G
The Journal of biological chemistry, vol. 282, (no. 18), pp. 13419-28, 2007/May/4. | Journal Article
 
Identification and Characterization of the Human Set1B Histone H3-Lys⁴ Methyltransferase Complex
Lee, Jeong-HeonTate, Courtney MYou, Jin-Sam and Skalnik, David G
Journal of biological chemistry., vol. 282, (no. 18), pp. 13419-13428, 2007. | Journal Article