61 Publications (Page 1 of 3)
2020
H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes
Kwon, Minjung⋅Park, Kihyun⋅Hyun, Kwangbeom⋅Lee, Jeong-Heon⋅Zhou, Linjiao⋅Cho, Young-Wook⋅Ge, Kai⋅Skalnik, David G⋅Muir, Tom W and Kim, Jaehoon
Nucleic acids research, 2020-May-04. | Journal Article
2018
Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2.
Higgs, Martin R⋅Sato, Koichi⋅Reynolds, John J⋅Begum, Shabana⋅Bayley, Rachel⋅Goula, Amalia⋅Vernet, Audrey⋅Paquin, Karissa L⋅Skalnik, David G⋅Kobayashi, Wataru⋅Takata, Minoru⋅Howlett, Niall G⋅Kurumizaka, Hitoshi⋅Kimura, Hiroshi and Stewart, Grant S
Molecular cell, June 7, 2018. | Journal Article
 
Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a
Kim, Kun-Yong⋅Kun-Yong, Kim⋅Kun-Yong, Kim⋅Tanaka, Yoshiaki⋅Tanaka, Yoshiaki⋅Tanaka, Yoshiaki⋅Su, Juan⋅Su, Juan⋅Su, Juan⋅Cakir, Bilal⋅Cakir, Bilal⋅Cakir, Bilal⋅Xiang, Yangfei⋅Patterson, Benjamin⋅Patterson, Benjamin⋅Patterson, Benjamin⋅Ding, Junjun⋅Ding, Junjun⋅Ding, Junjun⋅Jung, Yong-Wook⋅Ji-Hyun, Kim⋅Ji-Hyun, Kim⋅Kim, Ji-Hyun⋅Hysolli, Eriona⋅Hysolli, Eriona⋅Hysolli, Eriona⋅Lee, Haelim⋅Lee, Haelim⋅Lee, Haelim⋅Dajani, Rana⋅Dajani, Rana⋅Dajani, Rana⋅Kim, Jonghwan⋅Kim, Jonghwan⋅Kim, Jonghwan⋅Zhong, Mei⋅Zhong, Mei⋅Zhong, Mei⋅Lee, Jeong-Heon⋅Jeong-Heon, Lee⋅Jeong-Heon, Lee⋅Skalnik, David⋅Skalnik, David⋅Skalnik, David⋅Lim, Jeong Mook⋅Lim, Jeong M⋅Lim, Jeong M⋅Sullivan, Gareth J⋅Sullivan, Gareth J⋅Sullivan, Gareth J⋅Wang, Jianlong⋅Wang, Jianlong⋅Wang, Jianlong⋅Park, In-Hyun⋅Park, In-Hyun and Park, In-Hyun
Nature communications, vol. 9, (no. 1), pp. 13, 2018-07-03. | Journal Article
2016
Efficient differentiation of murine embryonic stem cells requires the binding of CXXC finger protein 1 to DNA or methylated histone H3-Lys4
Mahadevan, Jyothi and Skalnik, David G
Gene, vol. 594, (no. 1), pp. 9, 2016-12-05. | Journal Article
 
H3K4 Methyltransferase Set1a Is A Key Oct4 Coactivator Essential for Generation of Oct4 Positive Inner Cell Mass
Fang, Lan⋅Zhang, Jun⋅Zhang, Hui⋅Yang, Xiaoqin⋅Jin, Xueling⋅Zhang, Ling⋅Skalnik, David G⋅Jin, Ying⋅Zhang, Yong⋅Huang, Xingxu⋅Li, Jiwen and Wong, Jiemin
STEM CELLS, vol. 34, (no. 3), pp. 580, March 2016. | Journal Article
 
Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes
Alicea-Velázquez, Nilda L⋅Alicea-Velázquez, Nilda L⋅Shinsky, Stephen A⋅Shinsky, Stephen A⋅Loh, Daniel M⋅Loh, Daniel M⋅Lee, Jeong-Heon⋅Lee, Jeong-Heon⋅Skalnik, David G⋅Skalnik, David G⋅Cosgrove, Michael S and Cosgrove, Michael S
The Journal of biological chemistry, vol. 291, (no. 43), pp. 22372, 2016-Oct-21. | Journal Article
2014
The Epigenetic Regulator CXXC Finger Protein 1 is Essential for Murine Hematopoiesis
Chun, Kristin T⋅Chun, Kristin T⋅Li, Binghui⋅Li, Binghui⋅Dobrota, Erika⋅Dobrota, Erika⋅Tate, Courtney⋅Tate, Courtney⋅Lee, Jeong-Heon⋅Lee, Jeong-Heon⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Haneline, Laura⋅Haneline, Laura⋅HogenEsch, Harm⋅HogenEsch, Harm⋅Skalnik, David G and Skalnik, David G
PloS one, vol. 9, (no. 12), pp. e113745, 2014-00-00. | Journal Article
2012
Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells
Clouaire, Thomas⋅Webb, Shaun⋅Skene, Pete⋅Illingworth, Robert⋅Kerr, Alastair⋅Andrews, Robert⋅Lee, Jeong-Heon⋅Skalnik, David and Bird, Adrian
Genes & development, vol. 26, (no. 15), pp. 1728, 2012-Aug-01. | Journal Article
 
Dynamic Loss of H2B Ubiquitylation without Corresponding Changes in H3K4 Trimethylation during Myogenic Differentiation
Vethantham, Vasupradha⋅Vethantham, Vasupradha⋅Yang, Yan⋅Yang, Yan⋅Bowman, Christopher⋅Bowman, Christopher⋅Asp, Patrik⋅Asp, Patrik⋅Lee, Jeong-Heon⋅Lee, Jeong-Heon⋅Skalnik, David G⋅Skalnik, David⋅Dynlacht, Brian and Dynlacht, Brian D
Molecular and Cellular Biology, vol. 32, (no. 6), pp. 1055, 20120315. | Journal Article
 
Rbm15-Mkl1 Interacts with the Setd1b Histone H3-Lys4 Methyltransferase via a SPOC Domain That Is Required for Cytokine-Independent Proliferation
Lee, Jeong-Heon and Skalnik, David G
PloS one, vol. 7, (no. 8), pp. e42965, 2012-00-00. | Journal Article
 
Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases
Dharmarajan, Venkatasubramanian⋅Dharmarajan, Venkatasubramanian⋅Lee, Jeong-Heon⋅Lee, Jeong-Heon⋅Patel, Anamika⋅Patel, Anamika⋅Skalnik, David G⋅Skalnik, David G⋅Cosgrove, Michael S and Cosgrove, Michael S
The Journal of biological chemistry, vol. 287, (no. 33), pp. 27289, 2012-Aug-10. | Journal Article
2011
The Human Immunodeficiency Virus Protease Inhibitor Ritonavir Inhibits Lung Cancer Cells, in Part, by Inhibition of Survivin
Srirangam, Anjaiah⋅Srirangam, Anjaiah⋅Srirangam, Anjaiah⋅Srirangam, Anjaiah⋅Milani, Monica⋅Milani, Monica⋅Milani, Monica⋅Milani, Monica⋅Mitra, Ranjana⋅Mitra, Ranjana⋅Mitra, Ranjana⋅Mitra, Ranjana⋅Guo, Zhijun⋅Guo, Zhijun⋅Guo, Zhijun⋅Guo, Zhijun⋅Rodriguez, Mariangellys⋅Rodriguez, Mariangellys⋅Rodriguez, Mariangellys⋅Rodriguez, Mariangellys⋅Kathuria, Hitesh⋅Kathuria, Hitesh⋅Kathuria, Hitesh⋅Kathuria, Hitesh⋅Fukuda, Seiji⋅Fukuda, Seiji⋅Fukuda, Seiji⋅Fukuda, Seiji⋅Rizzardi, Anthony⋅Rizzardi, Anthony⋅Rizzardi, Anthony⋅Rizzardi, Anthony⋅Schmechel, Stephen⋅Schmechel, Stephen⋅Schmechel, Stephen⋅Schmechel, Stephen⋅Skalnik, David G⋅Skalnik, David G⋅Skalnik, David G⋅Skalnik, David G⋅Pelus, Louis M⋅Pelus, Louis M⋅Pelus, Louis M⋅Pelus, Louis M⋅Potter, David A⋅Potter, David A⋅Potter, David A and Potter, David A
Journal of Thoracic Oncology, vol. 6, (no. 4), pp. 670, April 2011. | Journal Article
2010
CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin.
Tate, Courtney M⋅Lee, Jeong-Heon and Skalnik, David G
The FEBS journal, vol. 277, (no. 1), pp. 210-23, 2010/Jan. | Journal Article
 
Identification and characterization of a novel human PP1 phosphatase complex.
Lee, Jeong-Heon⋅You, Jinsam⋅Dobrota, Erika and Skalnik, David G
The Journal of biological chemistry, vol. 285, (no. 32), pp. 24466-76, 2010/Aug/6. | Journal Article
 
The epigenetic regulator Cfp1
Skalnik, David G
Biomolecular concepts, vol. 1, (no. 5), pp. 334, 2010-12-01. | Journal Article
2009
CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation.
Tate, Courtney M⋅Lee, Jeong-Heon and Skalnik, David G
Molecular and cellular biology, vol. 29, (no. 14), pp. 3817-31, 2009/Jul. | Journal Article
 
DNA Methyltransferase Protein Synthesis Is Reduced in CXXC Finger Protein 1-Deficient Embryonic Stem Cells
Butler, JS⋅Butler, Jill S⋅Palam, LR⋅Palam, Lakshmi R⋅Tate, CM⋅Tate, Courtney M⋅Sanford, Jeremy⋅Sanford, Jeremy R⋅Wek, Ronald⋅Wek, Ronald C⋅Skalnik, David G and Skalnik, David G
DNA and Cell Biology, vol. 28, (no. 5), pp. 223-231, 2009. | Journal Article
 
Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity
Tate, Courtney M⋅Tate, Courtney M⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Holleran, Julianne L⋅Holleran, Julianne L⋅Egorin, Merrill J⋅Egorin, Merrill J⋅Skalnik, David G and Skalnik, David G
DNA Repair, vol. 8, (no. 12), pp. 1423, 2009. | Journal Article
 
Identification of a minimal cis-element and cognate trans-factor(s) required for induction of Rac2 gene expression during K562 cell differentiation.
Muthukrishnan, Rajarajeswari and Skalnik, David G
Gene, vol. 440, (no. 1-2), pp. 63-72, 2009/Jul/1. | Journal Article
 
Methyl group acceptance assay for the determination of global DNA methylation levels
Nephew, Kenneth P⋅Nephew, Ken⋅Balch, Curt⋅Balch, Curt⋅Skalnik, David G and Skalnik, David G
Methods in molecular biology (Clifton, N.J.), vol. 507, pp. 35, 2009-00-00. | Journal Article
2008
CFP1 Interacts with DNMT1 Independently of Association with the Setd1 Histone H3K4 Methyltransferase Complexes
Butler, JS⋅Lee, J-H and Skalnik, David G
DNA and Cell Biology, vol. 27, (no. 10), pp. 533-543, 2008. | Journal Article
 
Wdr82 Is a C-Terminal Domain-Binding Protein That Recruits the Setd1A Histone H3-Lys4 Methyltransferase Complex to Transcription Start Sites of Transcribed Human Genes
Lee, Jeong-Heon and Skalnik, David
Molecular and Cellular Biology, vol. 28, (no. 2), pp. 618, 20080115. | Journal Article
2007
CXXC Finger Protein 1 Is Required for Normal Proliferation and Differentiation of the PLB-985 Myeloid Cell Line
Young, SRL and Skalnik, David G
DNA and Cell Biology, vol. 26, (no. 2), pp. 80-90, 2007. | Journal Article
 
Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex.
Lee, Jeong-Heon⋅Tate, Courtney M⋅You, Jin-Sam and Skalnik, David G
The Journal of biological chemistry, vol. 282, (no. 18), pp. 13419-28, 2007/May/4. | Journal Article
 
Identification and Characterization of the Human Set1B Histone H3-Lys⁴ Methyltransferase Complex
Lee, Jeong-Heon⋅Tate, Courtney M⋅You, Jin-Sam and Skalnik, David G
Journal of biological chemistry., vol. 282, (no. 18), pp. 13419-13428, 2007. | Journal Article