The two main areas of interest are disorders of cardiac function (cardiomyopathies) and structure (congenital heart disease).
Dr. Ware’s research interests include the genetic and developmental basis of disorders of cardiac structure and function. Her research laboratory has made significant contributions in the areas of congenital heart defects and cardiomyopathy.
The lab is specifically interested in developmental pathways important for normal left-right patterning and cardiac looping during embryogenesis.
Research efforts in cardiomyopathy are focused on identifying novel causes of pediatric cardiomyopathy, delineating genetic modifiers utilizing genomic technologies for functional annotation and validation of genetic variants.
As the Program Leader in Cardiovascular Genetics, Dr. Ware coordinates clinical genetic services for patients with cardiomyopathy, genetic syndromic conditions, aortopathy and vascular disorders, and inherited arrhythmias.