19 Publications
2021
Cathepsin K Regulates Intraocular Pressure by Modulating Extracellular Matrix Remodeling and Actin-Bundling in the Trabecular Meshwork Outflow Pathway
Soundararajan, AvinashSoundararajan, AvinashSai, Supriya VWang, TingPattabiraman, Padmanabhan P and Pattabiraman, Padmanabhan P
Cells, vol. 10, (no. 11), 2021. | Journal Article
2020
Outflow Facility Effects of 3 Schlemm’s Canal Microinvasive Glaucoma Surgery Devices
Toris, Carol BPattabiraman, Padmanabhan PTye, GeorgeSamuelson, Thomas W and Rhee, Douglas J
Ophthalmology Glaucoma, vol. 3, (no. 2), pp. 121, March-April 2020. | Journal Article
2018
Discovery and Preclinical Development of Netarsudil, a Novel Ocular Hypotensive Agent for the Treatment of Glaucoma
Lin, Cheng-WenLin, Cheng-WenSherman, BryanSherman, BryanMoore, Lori AMoore, Lori ALaethem, Carmen LLaethem, Carmen LLu, Da-WenLu, Da-WenPattabiraman, Padmanabhan PPattabiraman, Padmanabhan PRao, Ponugoti VasanthaRao, Ponugoti VasanthadeLong, Mitchell AdeLong, Mitchell AKopczynski, Casey C and Kopczynski, Casey C
Journal of Ocular Pharmacology and Therapeutics, vol. 34, (no. 1-2), pp. 51, 2018-03-01. | Journal Article
 
Quantitative Proteomic Analysis of Human Aqueous Humor Using iTRAQ 4plex Labeling
Trzeciecka, AnnaPattabiraman, PadmanabhanPiqueras, Maria CarmenToris, Carol and Bhattacharya, Sanjoy K
Methods in molecular biology (Clifton, N.J.), vol. 1695, pp. 95, 2018-00-00. | Journal Article
2017
Rho Kinase in Eye Disease
Okumura, NaokiNakao, ShintaroInoue, Toshihiro and Pattabiraman, Padmanabhan
Journal of Ophthalmology, vol. 2017, pp. 2, 20170827. | Journal Article
 
Role of the Rho GTPase/Rho kinase signaling pathway in pathogenesis and treatment of glaucoma: Bench to bedside research
Rao, Ponugoti VasanthaRao, Ponugoti VasanthaPattabiraman, Padmanabhan PPattabiraman, Padmanabhan PKopczynski, Casey and Kopczynski, Casey
Experimental Eye Research, vol. 158, pp. 32, May 2017. | Journal Article
2016
The exit strategy: Pharmacological modulation of extracellular matrix production and deposition for better aqueous humor drainage
Pattabiraman, Padmanabhan P and Toris, Carol B
European Journal of Pharmacology, vol. 787, pp. 42, 2016-09-15. | Journal Article
2015
Elevated intraocular pressure induces Rho GTPase mediated contractile signaling in the trabecular meshwork
Pattabiraman, Padmanabhan PPattabiraman, Padmanabhan PInoue, ToshihiroInoue, ToshihiroRao, P. Vasantha and Rao, P Vasantha
Experimental Eye Research, vol. 136, pp. 33, July 2015. | Journal Article
 
Hic-5 Regulates Actin Cytoskeletal Reorganization and Expression of Fibrogenic Markers and Myocilin in Trabecular Meshwork Cells
Pattabiraman, Padmanabhan ParanjiPattabiraman, Padmanabhan ParanjiRao, Ponugoti Vasantha and Rao, Ponugoti Vasantha
Investigative ophthalmology & visual science, vol. 56, (no. 9), pp. 5669, 2015-Aug. | Journal Article
 
RhoA GTPase-Induced Ocular Hypertension in a Rodent Model Is Associated with Increased Fibrogenic Activity in the Trabecular Meshwork
Pattabiraman, Padmanabhan PPattabiraman, PadmanabhanRinkoski, TommyRinkoski, TommyPoeschla, EricPoeschla, EricProia, AlanProia, AlanChalla, PratapChalla, PratapRao, Ponugoti and Rao, Ponugoti V
American Journal of Pathology, The, vol. 185, (no. 2), pp. 512, 2015. | Journal Article
2014
Regulation of Plasticity and Fibrogenic Activity of Trabecular Meshwork Cells by Rho GTPase Signaling
Pattabiraman, Padmanabhan PPattabiraman, Padmanabhan PPattabiraman, Padmanabhan PMaddala, RupalathaMaddala, RupalathaMaddala, RupalathaRao, Ponugoti VasanthaRao, Ponugoti Vasantha and Rao, Vasanth
Journal of Cellular Physiology, vol. 229, (no. 7), pp. 942, July 2014. | Journal Article
2013
MRP4-Mediated Regulation of Intracellular cAMP and cGMP Levels in Trabecular Meshwork Cells and Homeostasis of Intraocular Pressure
Pattabiraman, Padmanabhan PPattabiraman, Padmanabhan PPecen, Paula EPecen, Paula ERao, Ponugoti Vasantha and Rao, Vasanth
Investigative ophthalmology & visual science, vol. 54, (no. 3), pp. 1649, 2013-Mar-05. | Journal Article
 
Regulation of Adherens Junctions in Trabecular Meshwork Cells by Rac GTPase and their influence on Intraocular Pressure
Pattabiraman, Padmanabhan PPattabiraman, Padmanabhan PEpstein, David LEpstein, David LRao, Ponugoti Vasantha and Rao, Ponugoti Vasantha
Journal of ocular biology, vol. 1, (no. 1), 2013-Jun-05. | Journal Article
2012
Connective Tissue Growth Factor–Mediated Upregulation of Neuromedin U Expression in Trabecular Meshwork Cells and its Role in Homeostasis of Aqueous Humor Outflow
Iyer, PadmaIyer, PadmaIyer, PadmaMaddala, RupalathaMaddala, RupalathaMaddala, RupalathaPattabiraman, Padmanabhan PPattabiraman, Padmanabhan PPattabiraman, Padmanabhan PRao, Ponugoti VasanthaRao, Ponugoti Vasantha and Rao, Vasanth
Investigative ophthalmology & visual science, vol. 53, (no. 8), pp. 4962, 2012-Jul-26. | Journal Article
 
The role of calcium-independent phospholipase A2γ in modulation of aqueous humor drainage and Ca2+ sensitization of trabecular meshwork contraction
Pattabiraman, Padmanabhan PPattabiraman, PadmanabhanLih, FredLih, Fred BTomer, Kenneth BTomer, KennethRao, Vasanth and Rao, Ponugoti
American Journal of Physiology - Cell Physiology, vol. 302, (no. 7), pp. 991, 2012-04-01. | Journal Article
2010
Characterization of Cytoskeleton-Enriched Protein Fraction of the Trabecular Meshwork and Ciliary Muscle Cells
Inoue, ToshihiroInoue, ToshihiroInoue, ToshihiroPecen, PaulaPecen, PaulaPecen, PaulaMaddala, RupalathaMaddala, RupalathaMaddala, RupalathaSkiba, Nikolai PSkiba, Nikolai PSkiba, NikolaiPattabiraman, Padmanabhan PPattabiraman, Padmanabhan PPattabiraman, Padmanabhan PEpstein, David LEpstein, David LEpstein, David LRao, P VRao, P Vasantha and Rao, P Vasantha
Investigative ophthalmology & visual science, vol. 51, (no. 12), pp. 6471, 2010-Dec. | Journal Article
 
Effects of chemical inhibition of N-WASP, a critical regulator of actin polymerization on aqueous humor outflow through the conventional pathway
Inoue, ToshihiroInoue, ToshihiroPattabiraman, Padmanabhan PPattabiraman, Padmanabhan PEpstein, David LEpstein, David LVasantha Rao, P and Vasantha Rao, P
Experimental Eye Research, vol. 90, (no. 2), pp. 367, 2010. | Journal Article
 
Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells
Pattabiraman, Padmanabhan PPattabiraman, PadmanabhanRao, Ponugoti and Rao, Vasanth
American Journal of Physiology - Cell Physiology, vol. 298, (no. 3), pp. 763, 2010-03-01. | Journal Article
2005
Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo
Pattabiraman, Padmanabhan PPattabiraman, Padmanabhan ParanjiTropea, DanielaTropea, DanielaChiaruttini, CristinaChiaruttini, CristinaTongiorgi, EnricoTongiorgi, EnricoCattaneo, AntoninoCattaneo, AntoninoDomenici, Luciano and Domenici, Luciano
Molecular and Cellular Neuroscience, vol. 28, (no. 3), pp. 570, 2005. | Journal Article