Molecular Biology/Biochemistry of the DNA synthetic apparatus of malignant and non-malignant cells. Proteomic genomic analysis of the components of the DNA synthetic apparatus of malignant and non-malignant cells. Exploring the biochemical basis for the induction of the malignant phenotype by carcinogenic metal ions. Role of DNA synthetic mediating aspects of the DNA damage repair process and reductions in DNA synthetic fidelity in malignant cells.
