Dr. Min You's researches are focused on the molecular mechanisms underlying the development of alcoholic fatty liver, especially in two areas: the effects of ethanol on the signaling pathways of lipid metabolism regulations in the liver, and ethanol regulation of adiponectin, a hormone derived from adipocytes, and its hepatic signaling. Since the effects of ethanol, either directly on signaling molecules in liver or indirectly on adiponectin synthesis in adipose, can be manipulated by dietary fatty acids or pharmacological agents, these studies may lead to novel therapeutic strategies for the treatment of alcoholic fatty liver diseases and possibly steatohepatitis.
