Expertise

Dr. Mendonca is an internationally known researcher with extensive expertise in X-ray and proton radiation biology related to the clinical uses of radiation. Dr. Mendonca’s research investigations are focused on gaining a better understanding of radiation’s ability to both heal and harm. His research can be generally separated into two main areas: 1) Understanding the mechanism of radiation-induced cancer and its prevention by natural antioxidants, and 2) Increasing the effectiveness of radiation as a treatment for lung and pancreatic cancers by biological (alteration of NF-kB activity and Warburg metabolism) and physical approaches (protons, nanoparticles, and FLASH) to improve tumor control and minimize damage to normal tissues.

Affiliations

Associate Vice Chancellor for Research, Indiana University-Purdue University Indianapolis

Professor, Department of Radiation Oncology, Indiana University School of Medicine

Adjunct Professor, Department of Medical and Molecular Genetics, Indiana University School of Medicine

Adjunct Assistant Professor, School of Health Sciences, College of Health and Human Sciences, Purdue University

Director, Radiation & Cancer Biology

Past Affiliations

Associate Professor, Department of Radiation Oncology, Indiana University School of Medicine

Adjunct Associate Professor, Department of Medical and Molecular Genetics, Indiana University School of Medicine

Member, Experimental Therapeutics Group

Associate Professor, Department of Radiation Oncology, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Associate Professor, Department of Medical and Molecular Genetics, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Melvin and Bren Simon Cancer Center, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Adjunct Assistant Professor, RadiationTherapy Option

Adjunct Assistant Professor, Medical and Molecular Genetics

Director, Department of Radiation Oncology, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Assistant Researcher I, Radiation Oncology

Post Graduate Researcher, Radiation Oncology

Graduate Student Research Assistant, Biophysics, University of California, Berkeley (past)

Teaching Associate, Physics and Biophysics, University of California, Berkeley (past)

Teaching Assistant, Physics and Biophysics, University of California, Berkeley (past)

Communities
Human Genetics, Radiation Oncology, Biomedical Science, Allied Health
Degrees
PhD, University of California, Berkeley, Biophysics, 1987
BA, College of the Holy Cross, Biology, 1978
Keywords
pancreatic cancer united states usa, midwest cancer biology cancer or carcinogenesis lung cancer biological response modifiers chemopreventive agents chemotherapeutic agents chemoprevention biological markers & sensor mechanisms biomedical research resources biological resources biomedical research resources, other cell lines biophysics beams (radiation) microgravity or reduced gravity experiments
Languages
German
Associations
Radiation Research Society
American Society of Therapeutic Radiology
American Association for Cancer Research
American Board of Radiology (ABR) Radiation Biology Task Force
Committee on Residency Training in Radiation Oncology, Education Commission, American College of Rad
American Association for the Advancement of Science
Sigma Xi