Expertise

Research Interests

  • Epithelial cell organization
  • Epithelial plasma membranes
  • Virtual tissue computer simulations
  • Kidney disease, ischemia
  • 3D imaging and informatics

My scientific focus has centered on the question as to how epithelial cells organize toform a functioning epithelium.

We have studied how this organization is achieved by examining processes that disrupt thepolarized features of epithelial. Ischemic injury has been shown to cause profoundderangements in epithelial organization and this is an area of intensive investigation inmy laboratory.


Expertise: Computational Biomedicine

Affiliations

Professor, Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine

Professor, Division of Nephrology, Department of Medicine, Indiana University School of Medicine

Weldon School of Biomedical Engineering, College of Engineering, Purdue University

Past Affiliations

Assistant Professor of Medicine, Nephrology

Assistant Professor of Medicine, Nephrology

Research Post-doctoral fellow, Cell Biology Program, European Molecular Biology Laboratory (EMBL) (past)

Instructor in Medicine, Nephrology

Adjunct Faculty, Department of Anatomy and Cell Biology, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Associate Professor, Department of Anatomy and Cell Biology, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Associate Professor, Anatomy and Cell Biology, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Communities
Nephrology, Biomedical Engineering, Human Anatomy, Cell Biology
Degrees
MD, University of Chicago, 1980
BS, Northwestern University, 1976
Keywords
traumatology, accidents & injury kidney disease gene cloning genetic manipulation molecular cloning molecular probes nucleic acid sequencing internal medicine nephrology cell & developmental biology biochemistry & molecular biology genetics microscopy
Languages
English
Honors

Scientific Advisory Board of the Polycystic Kidney Disease Research Foundation (Polycystic Kidney Disease), Polycystic Kidney Disease Research Founcation, 2000-2003

Central Society for Clinical Research (Medical Research), Central Society for Clinical Research, 1999

Clinician Scientist Award (Nephrology), National Kidney Foundation, 1995-1998

Distinguished Faculty Award, Northwestern University, 1995

Woods Hole Cell Physiology Course (Cellular Physiology), Woods Hole Marine Biology Laboratory, 1990

Burrough Wellcome National Kidney Foundation Fellowship, National Kidney Foundation, 1985-1987

Tau Beta Pi (Engineering Honor Society), Northwestern University, 1975

Associations
American Association for the Advancement of Science
American Society for Cell Biology
American Society of Nephrology
Central Society for Clinical Research