137 Publications (Page 1 of 6)
2020
Multicenter phase 2 trial of nintedanib in advanced nonpancreatic neuroendocrine tumorsIyer, Renuka V⋅Konda, Bhavana⋅Fountzilas, Christos⋅Mukherjee, Sarbajit⋅Owen, Dwight⋅Attwood, Kristopher⋅Wang, Chong⋅Hicks, Karen⋅Wilton, John⋅Bies, Robert⋅Casucci, Danielle and Shah, ManishaCancer, vol. 126, (no. 16), pp. 3689-3697, Aug 2020.
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Optimal Sampling Strategies for Irinotecan (CPT-11) and its Active Metabolite (SN-38) in Cancer PatientsKaras, Spinel⋅Etheridge, Amy S⋅Tsakalozou, Eleftheria⋅Ramírez, Jacqueline⋅Cecchin, Erika⋅van Schaik, Ron H N⋅Toffoli, Giuseppe⋅Ratain, Mark J⋅Mathijssen, Ron H J⋅Forrest, Alan⋅Bies, Robert R and Innocenti, FedericoThe AAPS journal, vol. 22, (no. 3), pp. 59, 2020-03-17.
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2019
Circadian patterns of hallucinatory experiences in patients with schizophrenia: Potentials for chrono-pharmacologyKoizumi, Teruki⋅Suzuki, Takefumi⋅Pillai, Nikhil Sasidharan⋅Bies, Robert R⋅Takeuchi, Hiroyoshi⋅Yoshimura, Kimio⋅Mimura, Masaru and Uchida, HiroyukiJournal of Psychiatric Research, vol. 117, pp. 6, October 2019.
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Comment on Jaki et al., A proposal for a new PhD level curriculum on quantitative methods for drug development. Pharmaceutical Statistics 17 (5):593–606, Sep/Oct 2018, DOI: 10.1002/pst.1873Krause, Andreas⋅Kloft, Charlotte⋅Huisinga, Wilhelm⋅Karlsson, Mats⋅Pinheiro, José⋅Bies, Robert⋅Rogers, James⋅Mentré, France and Musser, Bret JPharmaceutical Statistics, vol. 18, (no. 3), pp. 281, May/June 2019.
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Estimating parameters of nonlinear dynamic systems in pharmacology using chaos synchronization and grid searchPillai, Nikhil⋅Schwartz, Sorell⋅Ho, Thang⋅Dokoumetzidis, Aris⋅Bies, Robert and Freedman, ImmanuelJournal of Pharmacokinetics and Pharmacodynamics, vol. 46, (no. 2), pp. 210, 20190401.
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Estimation of Solid Tumor Doubling Times from Progression-Free Survival Plots Using a Novel Statistical Approach.Kay, Katherine⋅Dolcy, Keith⋅Bies, Robert and Shah, Dhaval KThe AAPS journal, vol. 21, (no. 2), pp. 27, February 8, 2019.
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Model-Guided Antipsychotic Dose Reduction in Schizophrenia: A Pilot, Single-Blind Randomized Controlled TrialOzawa, Chisa⋅Bies, Robert R⋅Pillai, Nikhil⋅Suzuki, Takefumi⋅Mimura, Masaru and Uchida, HiroyukiJournal of clinical psychopharmacology, vol. 39, (no. 4), pp. 335, 2019 Jul/Aug.
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Panos Macheras: a pioneering scientist in pharmaceutical scienceEndrenyi, Laszlo and Bies, RobertJournal of Pharmacokinetics and Pharmacodynamics, vol. 46, (no. 2), pp. 109, 20190401.
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Pharmacokinetics and pharmacodynamics of ropinirole in patients with prolactinomasLiu, Sihang⋅Hu, Can⋅Peters, Jane⋅Tsang, Amanda⋅Cremers, Serge⋅Bies, Robert and Page‐Wilson, GabrielleBritish Journal of Clinical Pharmacology, vol. 85, (no. 2), pp. 376, February 2019.
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Prediction of Nephropathy in Type 2 Diabetes: An Analysis of the ACCORD Trial Applying Machine Learning TechniquesRodriguez‐Romero, Violeta⋅Bergstrom, Richard F⋅Decker, Brian S⋅Lahu, Gezim⋅Vakilynejad, Majid and Bies, Robert RClinical and Translational Science, vol. 12, (no. 5), pp. 528, September 2019.
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Preface to Special Issue for Panos MacherasBies, RobertJournal of Pharmacokinetics and Pharmacodynamics, vol. 46, (no. 2), pp. 103, 20190401.
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2018
Chaos synchronization and Nelder-Mead search for parameter estimation in nonlinear pharmacological systems: Estimating tumor antigenicity in a model of immunotherapyPillai, Nikhil⋅Pillai, Nikhil⋅Craig, Morgan⋅Craig, Morgan⋅Dokoumetzidis, Aristeidis⋅Dokoumetzidis, Aristeidis⋅Schwartz, Sorell L⋅Schwartz, Sorell L.⋅Bies, Robert⋅Bies, Robert⋅Freedman, Immanuel and Freedman, ImmanuelProgress in Biophysics and Molecular Biology, vol. 139, pp. 30, November 2018.
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Mathematical modeling of intracrine androgen metabolism in prostate cancer: Methodological aspects.Cook, Sarah F⋅Cook, Sarah F.⋅Fiandalo, Michael V⋅Fiandalo, Michael V.⋅Watt, David S⋅Watt, David S.⋅Wu, Yue⋅Wu, Yue⋅Mohler, James L⋅Mohler, James L.⋅Bies, Robert R. and Bies, Robert RThe Prostate, June 25, 2018.
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Physiologically‐based pharmacokinetic model of vaginally administered dapivirine ring and film formulationsKay, Katherine⋅Shah, Dhaval K⋅Rohan, Lisa and Bies, RobertBritish Journal of Clinical Pharmacology, vol. 84, (no. 9), pp. 1969, September 2018.
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The clinical utility of pharmacometric modelsKumar, Shaun S⋅Biltaji, Eman⋅Bies, Robert and Sherwin, Catherine MBritish Journal of Clinical Pharmacology, vol. 84, (no. 7), pp. 1414, July 2018.
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2017
Population Pharmacokinetic Modeling To Estimate the Contributions of Genetic and Nongenetic Factors to Efavirenz DispositionRobarge, Jason D⋅Robarge, Jason D⋅Robarge, Jason D⋅Metzger, Ingrid F⋅Metzger, Ingrid F⋅Metzger, Ingrid F⋅Lu, Jessica⋅Lu, Jessica⋅Lu, Jessica⋅Thong, Nancy⋅Thong, Nancy⋅Thong, Nancy⋅Skaar, Todd C⋅Skaar, Todd C⋅Skaar, Todd C⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Bies, Robert R⋅Bies, Robert R and Bies, Robert RAntimicrobial agents and chemotherapy, vol. 61, (no. 1), 2017-01-00.
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2016
A population pharmacokinetic model for R- and S-citalopram and desmethylcitalopram in Alzheimer's disease patients with agitation.Akil, Ayman⋅Bies, Robert R⋅Pollock, Bruce G⋅Avramopoulos, Dimitrios⋅Devanand, D P⋅Mintzer, Jacobo E⋅Porsteinsson, Anton P⋅Schneider, Lon S⋅Weintraub, Daniel⋅Yesavage, Jerome⋅Shade, David M and Lyketsos, Constantine GJournal of pharmacokinetics and pharmacodynamics, vol. 43, (no. 1), pp. 99-109, February 2016.
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A Uridine Glucuronosyltransferase 2B7 Polymorphism Predicts Epirubicin Clearance and Outcomes in Early-Stage Breast Cancer.Sawyer, Michael B⋅Pituskin, Edith⋅Damaraju, Sambasivarao⋅Bies, Robert R⋅Vos, Larissa J⋅Prado, Carla M M⋅Kuzma, Michelle⋅Scarfe, Andrew G⋅Clemons, Mark⋅Tonkin, Katia⋅Au, Heather-Jane⋅Koski, Sheryl⋅Joy, Anil A⋅Smylie, Michael⋅King, Karen⋅Carandang, Diana⋅Damaraju, Vijaya L⋅Hanson, John⋅Cass, Carol E and Mackey, John RClinical breast cancer, vol. 16, (no. 2), pp. 139-44.e1-3, April 2016.
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Big Data: Challenges and opportunities for clinical pharmacology.Flockhart, David⋅Bies, Robert R⋅Gastonguay, Marc R and Schwartz, Sorell L(pp. 804-806). May 2016
Comparative Effects of CT Imaging Measurement on RECIST End Points and Tumor Growth Kinetics Modeling.Li, C H⋅Bies, R R⋅Wang, Y⋅Sharma, M R⋅Karovic, S⋅Werk, L⋅Edelman, M J⋅Miller, A A⋅Vokes, E E⋅Oto, A⋅Ratain, M J⋅Schwartz, L H and Maitland, M LClinical and translational science, vol. 9, (no. 1), pp. 43-50, February 2016.
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Disease Progression Modeling: Key Concepts and Recent Developments.Cook, Sarah F and Bies, Robert RCurrent pharmacology reports, vol. 2, (no. 5), pp. 221-230, October 2016.
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Dopamine D2/3 Receptor Occupancy Following Dose Reduction Is Predictable With Minimal Plasma Antipsychotic Concentrations: An Open-Label Clinical Trial.Nakajima, Shinichiro⋅Uchida, Hiroyuki⋅Bies, Robert R⋅Caravaggio, Fernando⋅Suzuki, Takefumi⋅Plitman, Eric⋅Mar, Wanna⋅Gerretsen, Philip⋅Pollock, Bruce G⋅Mulsant, Benoit H⋅Mamo, David C and Graff-Guerrero, ArielSchizophrenia bulletin, vol. 42, (no. 1), pp. 212-219, January 2016.
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Increasing Versus Maintaining the Dose of Olanzapine or Risperidone in Schizophrenia Patients Who Did Not Respond to a Modest Dosage: A Double-Blind Randomized Controlled Trial.Sakurai, Hitoshi⋅Suzuki, Takefumi⋅Bies, Robert R⋅Pollock, Bruce G⋅Mimura, Masaru⋅Kapur, Shitij and Uchida, HiroyukiThe Journal of clinical psychiatry, vol. 77, (no. 10), pp. 1381-1390, October 2016.
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Obituary: David Alastair Flockhart , MD, PhD.Bies, Robert⋅McDonald, Christine and Desta, ZeruesenayBritish journal of clinical pharmacology, vol. 81, (no. 2), pp. 393-394, February 2016.
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Organised crime against the academic peer review system.Gilchrist, Annette⋅Cohen, Adam⋅Pattanaik, Smita⋅Kumar, Praveen⋅Bies, Robert R⋅de Boer, Anthonius⋅Ferro, Albert⋅Gilchrist, Annette⋅Isbister, Geoffrey K⋅Ross, Sarah and Webb, Andrew J(pp. 1012-1017). June 2016