Dr. Kunal Gupta is a functional neurosurgeon, specializing in the open and minimally invasive treatment of movement disorders and epilepsy.
Clinical Interests:
- Deep brain stimulation, thalamotomy, pallidotomy, laser interstitial thermal therapy, responsive neurostimulation, vagal nerve stimulation, resection of epilepsy focus, stereoelectroencephalography, microvascular decompression, radiofrequency ablation, peripheral nerve decompression, peripheral nerve transfer
Dr. Kunal Gupta is investigating the molecular mechanisms responsible for the development of temporal lobe epilepsy. He and his group are working to identify new targets to treat and prevent the development of epilepsy in high-risk groups as well as surgical recurrence. He is also studying how the human brain processes information, and is investigating how new surgical methods can be used to treat medically refractory epilepsy.
In our lab, we use mouse models of temporal lobe epilepsy to investigate pathological remodeling in the epileptogenic zone and connected seizure network, to determine the biological basis for the formation of these critical clinical regions. We do this by investigating:
- Adult hippocampal epileptogenesis
- Region-specific gene pathway dysregulation
- Therapeutic molecular pathway modulation
