19 Publications
2020
Uromodulin (Tamm-Horsfall protein): guardian of urinary and systemic homeostasis
Micanovic, Radmila⋅LaFavers, Kaice⋅Garimella, Pranav S⋅Wu, Xue-Ru and El-Achkar, Tarek M
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, vol. 35, (no. 1), pp. 43, 2020-01-01. | Journal Article
2019
Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel
LaFavers, Kaice A⋅LaFavers, Kaice A⋅LaFavers, Kaice A⋅LaFavers, Kaice A.⋅LaFavers, Kaice A⋅LaFavers, Kaice A⋅Macedo, Etienne⋅Macedo, Etienne⋅Macedo, Etienne⋅Macedo, Etienne⋅Macedo, Etienne⋅Macedo, Etienne⋅Garimella, Pranav S.⋅Garimella, Pranav S⋅Garimella, Pranav S⋅Garimella, Pranav S⋅Garimella, Pranav S⋅Garimella, Pranav S⋅Lima, Camila⋅Lima, Camila⋅Lima, Camila⋅Lima, Camila⋅Lima, Camila⋅Lima, Camila⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Myslinski, Jered⋅Myslinski, Jered⋅Myslinski, Jered⋅Myslinski, Jered⋅Myslinski, Jered⋅Myslinski, Jered⋅McClintick, Jeanette⋅McClintick, Jeanette⋅McClintick, Jeanette⋅McClintick, Jeanette⋅McClintick, Jeanette⋅Mc Clintick, Jeanette⋅Witzmann, Frank A⋅Witzmann, Frank A⋅Witzmann, Frank A⋅Witzmann, Frank A⋅Witzmann, Frank A⋅Witzmann, Frank A.⋅Winfree, Seth⋅Winfree, Seth⋅Winfree, Seth⋅Winfree, Seth⋅Winfree, Seth⋅Winfree, Seth⋅Phillips, Carrie L⋅Phillips, Carrie L⋅Phillips, Carrie L⋅Phillips, Carrie L⋅Phillips, Carrie L.⋅Phillips, Carrie L⋅Hato, Takashi⋅Hato, Takashi⋅Hato, Takashi⋅Hato, Takashi⋅Hato, Takashi⋅Hato, Takashi⋅Dagher, Pierre C⋅Dagher, Pierre C.⋅Dagher, Pierre C⋅Dagher, Pierre C⋅Dagher, Pierre C⋅Dagher, Pierre C⋅Wu, Xue-Ru⋅Wu, Xue-Ru⋅Wu, Xue-Ru⋅Wu, Xue-Ru⋅Wu, Xue-Ru⋅Wu, Xue-Ru⋅El-Achkar, Tarek M⋅El-Achkar, Tarek M.⋅El-Achkar, Tarek M⋅El-Achkar, Tarek M⋅El-Achkar, Tarek M⋅El-Achkar, Tarek M⋅Micanovic, Radmila⋅Micanovic, Radmila⋅Micanovic, Radmila⋅Micanovic, Radmila⋅Micanovic, Radmila and Micanovic, Radmila
Science translational medicine, vol. 11, (no. 512), pp. eaaw3639, 2019-10-02. | Journal Article
2018
Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney
Micanovic, Radmila⋅Micanovic, Radmila⋅Micanovic, Radmila⋅Micanovic, Radmila⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Janosevic, Danielle⋅Janosevic, Danielle⋅Janosevic, Danielle⋅Janosevic, Danielle⋅Lee, Maya E⋅Lee, Maya E⋅Lee, Maya E⋅Lee, Maya E⋅Hato, Takashi⋅Hato, Takashi⋅Hato, Takashi⋅Hato, Takashi⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Winfree, Seth⋅Winfree, Seth⋅Winfree, Seth⋅Winfree, Seth⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Tong, Yan⋅Tong, Yan⋅Tong, Yan⋅Tong, Yan⋅Rice, Susan E⋅Rice, Susan E⋅Rice, Susan E⋅Rice, Susan E⋅Dagher, Pierre C⋅Dagher, Pierre C⋅Dagher, Pierre C⋅Dagher, Pierre C⋅Wu, Xue-Ru⋅Wu, Xue-Ru⋅Wu, Xue-Ru⋅Wu, Xue-Ru⋅El-Achkar, Tarek M⋅El-Achkar, Tarek M⋅El-Achkar, Tarek M and El-Achkar, Tarek M
Journal of the American Society of Nephrology : JASN, vol. 29, (no. 3), pp. 856, 2018-03-00. | Journal Article
2017
Quantitative Three-Dimensional Tissue Cytometry to Study Kidney Tissue and Resident Immune Cells
Winfree, Seth⋅Winfree, Seth⋅Winfree, Seth⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Micanovic, Radmila⋅Micanovic, Radmila⋅Micanovic, Radmila⋅Eadon, Michael T⋅Eadon, Michael T⋅Eadon, Michael T⋅Kelly, Katherine J⋅Kelly, Katherine J⋅Kelly, Katherine J⋅Sutton, Timothy A⋅Sutton, Timothy A⋅Sutton, Timothy A⋅Phillips, Carrie L⋅Phillips, Carrie L⋅Phillips, Carrie L⋅Dunn, Kenneth W⋅Dunn, Kenneth W⋅Dunn, Kenneth W⋅El-Achkar, Tarek M⋅El-Achkar, Tarek M and El-Achkar, Tarek M
Journal of the American Society of Nephrology : JASN, vol. 28, (no. 7), pp. 2118, 2017-Jul. | Journal Article
2015
Immunofluorescence laser micro-dissection of specific nephron segments in the mouse kidney allows targeted downstream proteomic analysis.
Micanovic, Radmila⋅Khan, Shehnaz and El-Achkar, Tarek M
Physiological reports, vol. 3, (no. 2), February 1, 2015. | Journal Article
 
Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.
Micanovic, Radmila⋅Micanovic, Radmila⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R⋅Dagher, Pierre C⋅Dagher, Pierre C⋅Srour, Edward F⋅Srour, Edward F⋅Khan, Shehnaz⋅Khan, Shehnaz⋅Hato, Takashi⋅Hato, Takashi⋅Lyle, Allison⋅Lyle, Allison⋅Tong, Yan⋅Tong, Yan⋅Wu, Xue-Ru⋅Wu, Xue-Ru⋅El-Achkar, Tarek M and El-Achkar, Tarek M
Journal of the American Society of Nephrology : JASN, vol. 26, (no. 9), pp. 2172-2182, September 2015. | Journal Article
2014
An intricate network of conserved DNA upstream motifs and associated transcription factors regulate the expression of uromodulin gene.
Srivastava, Rajneesh⋅Micanovic, Radmila⋅El Achkar, Tarek M and Janga, Sarath C
The Journal of urology, vol. 192, (no. 3), pp. 981-9, 2014/Sep. | Journal Article
 
The Role of Tumor Necrosis Factor Alpha in Regulating the Expression of Tamm-Horsfall Protein (Uromodulin) in Thick Ascending Limbs during Kidney Injury
Heitmeier, Monique⋅McCracken, Ruth⋅Micanovic, Radmila⋅Khan, Shehnaz and El-Achkar, Tarek M
American Journal of Nephrology, vol. 40, (no. 5), pp. 467, 20141200. | Journal Article
2013
Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319.
Kharitonenkov, Alexei⋅Beals, John M⋅Micanovic, Radmila⋅Strifler, Beth A⋅Rathnachalam, Radhakrishnan⋅Wroblewski, Victor J⋅Li, Shun⋅Koester, Anja⋅Ford, Amy M⋅Coskun, Tamer⋅Dunbar, James D⋅Cheng, Christine C⋅Frye, Christopher C⋅Bumol, Thomas F and Moller, David E
PloS one, vol. 8, (no. 3), pp. e58575, 2013. | Journal Article
2012
Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo
Adams, Andrew⋅Coskun, Tamer⋅Irizarry Rovira, Armando⋅Schneider, Michael⋅Raches, David⋅Micanovic, Radmila⋅Bina, Holly⋅Dunbar, James and Kharitonenkov, Alexei
PLoS One, vol. 7, (no. 5), May 2012. | Journal Article
2009
Different roles of N‐ and C‐ termini in the functional activity of FGF21
Micanovic, Radmila⋅Raches, David W⋅Dunbar, James D⋅Driver, David A⋅Bina, Holly A⋅Dickinson, Craig D and Kharitonenkov, Alexei
Journal of Cellular Physiology, vol. 219, (no. 2), pp. 234, May 2009. | Journal Article
2008
FGF-21/FGF-21 receptor interaction and activation is determined by betaKlotho
Kharitonenkov, Alexei⋅Dunbar, James D⋅Bina, Holly A⋅Bright, Stuart⋅Moyers, Julie S⋅Zhang, Chen⋅Ding, Liyun⋅Micanovic, Radmila⋅Mehrbod, Sean F⋅Knierman, Michael D⋅Hale, John E⋅Coskun, Tamer and Shanafelt, Armen B
Journal of cellular physiology, vol. 215, (no. 1), pp. 1, 2008-Apr. | Journal Article
 
FGF‐21/FGF‐21 receptor interaction and activation is determined by βKlotho
Kharitonenkov, Alexei⋅Dunbar, James D⋅Bina, Holly A⋅Bright, Stuart⋅Moyers, Julie S⋅Zhang, Chen⋅Ding, Liyun⋅Micanovic, Radmila⋅Mehrbod, Sean F⋅Knierman, Michael D⋅Hale, John E⋅Coskun, Tamer and Shanafelt, Armen B
Journal of Cellular Physiology, vol. 215, (no. 1), pp. 7, April 2008. | Journal Article
2005
FGF-21 as a novel metabolic regulator
Kharitonenkov, Alexei⋅Kharitonenkov, Alexei⋅Shiyanova, Tatiyana L⋅Shiyanova, Tatiyana L⋅Koester, Anja⋅Koester, Anja⋅Ford, Amy M⋅Ford, Amy M⋅Micanovic, Radmila⋅Micanovic, Radmila⋅Galbreath, Elizabeth J⋅Galbreath, Elizabeth J⋅Sandusky, George E⋅Sandusky, George E⋅Hammond, Lisa J⋅Hammond, Lisa J⋅Moyers, Julie S⋅Moyers, Julie S⋅Owens, Rebecca A⋅Owens, Rebecca A⋅Gromada, Jesper⋅Gromada, Jesper⋅Brozinick, Joseph T⋅Brozinick, Joseph T⋅Hawkins, Eric D⋅Hawkins, Eric D⋅Wroblewski, Victor J⋅Wroblewski, Victor J⋅Li, De-Shan⋅Li, De-Shan⋅Mehrbod, Farrokh⋅Mehrbod, Farrokh⋅Jaskunas, S Richard⋅Jaskunas, S Richard⋅Shanafelt, Armen B and Shanafelt, Armen B
The Journal of clinical investigation, vol. 115, (no. 6), pp. 1635, 2005-Jun. | Journal Article
 
LY2116419 Has Extended Time-Action and near Native Affinity for IGF-1 Receptor
Micanovic, Radmila⋅Kohn, Wayne⋅Myers, Sharon and Vick, Andrew
Diabetes, vol. 54, pp. A512, 20050601. | Journal Article
2003
Decoy receptor 3 (DcR3) is proteolytically processed to a metabolic fragment having differential activities against Fas ligand and LIGHT
Wroblewski, Victor J⋅Witcher, Derrick R⋅Becker, Gerald W⋅Davis, Kelly A⋅Dou, Shenshen⋅Micanovic, Radmila⋅Newton, Christy M⋅Noblitt, Timothy W⋅Richardson, John M⋅Song, Ho Yeong and Hale, John E
Biochemical Pharmacology, vol. 65, (no. 4), pp. 667, 2003. | Journal Article
2002
Glycosylation of Erythropoietin Affects Receptor Binding Kinetics:  Role of Electrostatic Interactions
Darling, Ryan J⋅Kuchibhotla, Uma⋅Glaesner, Wolfgang⋅Micanovic, Radmila⋅Witcher, Derrick R and Beals, John M
Biochemistry, vol. 41, (no. 49), pp. 14531, 20021210. | Journal Article
1991
Structural requirements of a nascent protein for processing to a PI-G anchored form: Studies in intact cells and cell-free systems
Udenfriend, Sidney⋅Micanovic, Radmila and Kodukula, Krishna
Cell Biology International Reports, vol. 15, (no. 9), pp. 759, 1991. | Journal Article
1990
Selectivity of the Cleavage/Attachment Site of Phosphatidylinositol-Glycan- Anchored Membrane Proteins Determined by Site-Specific Mutagenesis at Asp- 484 of Placental Alkaline Phosphatase
Micanovic, Radmila⋅Gerber, Louise⋅Berger, Joel⋅Kodukula, Krishna and Udenfriend, Sidney
Proceedings of the National Academy of Sciences of the United States of America, vol. 87, (no. 1), pp. 161, 19900101. | Journal Article