9 Publications
2017
Directed Differentiation of Mouse Embryonic Stem Cells Into Inner Ear Sensory Epithelia in 3D Culture.
Nie, Jing⋅Nie, Jing⋅Koehler, Karl R⋅Koehler, Karl R⋅Hashino, Eri and Hashino, Eri
Methods in molecular biology (Clifton, N.J.), vol. 1597, pp. 67-83, 2017. | Journal Article
 
Generation of inner ear organoids containing functional hair cells from human pluripotent stem cells
Koehler, Karl⋅Koehler, Karl R⋅Koehler, Karl R⋅Koehler, Karl R⋅Nie, Jing⋅Nie, Jing⋅Nie, Jing⋅Longworth-Mills, Emma⋅Longworth-mills, Emma⋅Longworth-Mills, Emma⋅Longworth-Mills, Emma⋅Liu, Xiao-Ping⋅Liu, Xiao-Ping⋅Liu, Xiao-Ping⋅Liu, Xiao-ping⋅Lee, Jiyoon⋅Lee, Jiyoon⋅Lee, Jiyoon⋅Lee, Jiyoon⋅Holt, Jeffrey⋅Holt, Jeffrey R⋅Holt, Jeffrey R⋅Holt, Jeffrey R⋅Hashino, Eri⋅Hashino, Eri and Hashino, Eri
Nature Biotechnology, vol. 35, (no. 6), pp. 583-589, Jun 2017. | Journal Article
2016
Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells.
Liu, Xiao-Ping⋅Koehler, Karl R⋅Mikosz, Andrew M⋅Hashino, Eri and Holt, Jeffrey R
Nature communications, vol. 7, pp. 11508, May 24, 2016. | Journal Article
 
Generating Inner Ear Organoids from Mouse Embryonic Stem Cells.
Longworth-Mills, Emma⋅Koehler, Karl R and Hashino, Eri
Methods in molecular biology (Clifton, N.J.), vol. 1341, pp. 391-406, 2016. | Journal Article
 
Modulation of Wnt Signaling Enhances Inner Ear Organoid Development in 3D Culture
DeJonge, Rachel E⋅DeJonge, Rachel E⋅Liu, Xiao-Ping⋅Liu, Xiao-Ping⋅Deig, Christopher R⋅Deig, Christopher R⋅Heller, Stefan⋅Heller, Stefan⋅Koehler, Karl R⋅Koehler, Karl R⋅Hashino, Eri and Hashino, Eri
PLoS One, vol. 11, (no. 9), Sep 2016. | Journal Article
2015
Tlx3 promotes glutamatergic neuronal subtype specification through direct interactions with the chromatin modifier CBP.
Shimomura, Atsushi⋅Patel, Dharmeshkumar⋅Wilson, Sarah M⋅Koehler, Karl R⋅Khanna, Rajesh and Hashino, Eri
PloS one, vol. 10, (no. 8), pp. e0135060, 2015. | Journal Article
2014
3D mouse embryonic stem cell culture for generating inner ear organoids.
Koehler, Karl R⋅Koehler, Karl R⋅Hashino, Eri and Hashino, Eri
Nature protocols, vol. 9, (no. 6), pp. 1229-1244, 2014. | Journal Article
2013
Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture.
Koehler, Karl R⋅Koehler, Karl R⋅Mikosz, Andrew M⋅Mikosz, Andrew M⋅Molosh, Andrei I⋅Molosh, Andrei I⋅Patel, Dharmeshkumar⋅Patel, Dharmeshkumar⋅Hashino, Eri and Hashino, Eri
Nature, vol. 500, (no. 7461), pp. 217-221, August 8, 2013. | Journal Article
2011
Extended passaging increases the efficiency of neural differentiation from induced pluripotent stem cells.
Koehler, Karl R⋅Tropel, Philippe⋅Theile, Jonathan W⋅Kondo, Takako⋅Cummins, Theodore R⋅Viville, Stéphane and Hashino, Eri
BMC neuroscience, vol. 12, pp. 82, 2011. | Journal Article