Second, we have begun studying the role of Mdm2 and megakaryocytes in regulating tumor progression and metastasis in osteosarcoma.
To achieve this goal, her research program focuses in five areas: 1) The role of megakaryocytes, megakaryocyte growth factors and their receptors in bone homeostasis; 2) Osteoblasts and the hematopoietic stem cell niche; 3) Regulators of osteosarcoma tumor growth; 4) Translational/clinical studies examining the genetic regulation of skeletal homeostasis; and 5) The molecular mechanisms underlying bone repair/fracture healing.
Subject areas:
- Pediatric Musculoskeletal Disease
- Trauma Regeneration and Rehabilitation
Research: Cellular and Molecular Metabolism
