16 Publications
2014
Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated α-synuclein.
Oh, MisookLee, Ji HWang, WeiLee, Hui SLee, Woo SBurlak, ChristopherIm, WonpilHoang, Quyen Q and Lim, Hyun Suk
Proceedings of the National Academy of Sciences of the United States of America, vol. 111, (no. 30), pp. 11007-12, 2014/Jul/29. | Journal Article
2013
Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth.
Adler, Jacob JHeller, Brigitte LBringman, Lauren RRanahan, WilliamCocklin, Ross RGoebl, Mark GOh, MisookLim, Hyun SukIngham, Robert and Wells, Clark D
The Journal of biological chemistry, vol. 288, (no. 21), pp. 15181-93, 2013/May/24. | Journal Article
2012
Application of Binding Free Energy Calculations to Prediction of Binding Modes and Affinities of MDM2 and MDMX Inhibitors
Lee, Hui SJo, SunhwanLim, Hyun Suk and Im, Wonpil
Journal of Chemical Information and Modeling, vol. 52, (no. 7), Jul 23, 2012. | Journal Article
 
Solid-phase synthesis of tetrasubstituted pyrrolo[2,3-d]pyrimidines.
Lee, Ji H and Lim, Hyun Suk
Organic & biomolecular chemistry, vol. 10, (no. 21), pp. 4229-35, 2012/Jun/7. | Journal Article
2011
Design and facile solid-phase synthesis of conformationally constrained bicyclic peptoids.
Lee, Ji HKim, Han-Sung and Lim, Hyun Suk
Organic letters, vol. 13, (no. 19), pp. 5012-5, 2011/Oct/7. | Journal Article
 
Novel pyrrolopyrimidine-based α-helix mimetics: cell-permeable inhibitors of protein−protein interactions.
Lee, Ji HZhang, QiJo, SunhwanChai, Sergio COh, MisookIm, WonpilLu, Hua and Lim, Hyun Suk
Journal of the American Chemical Society, vol. 133, (no. 4), pp. 676-9, 2011/Feb/2. | Journal Article
 
Reductively degradable polyester-based block copolymers prepared by facile polycondensation and ATRP: synthesis, degradation, and aqueous micellization
Nelson-Mendez, AndrewAleksanian, SamuelOh, MisookLim, Hyun Suk and Oh, Jung K
Soft Matter, vol. 7, (no. 16), pp. 7441-7452, 2011. | Journal Article
2010
A simple strategy for the construction of combinatorial cyclic peptoid libraries.
Lee, Ji HMeyer, Amanda M and Lim, Hyun Suk
Chemical communications (Cambridge, England), vol. 46, (no. 45), pp. 8615-7, 2010/Dec/7. | Journal Article
 
Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates.
Lee, JiyongLee, JiyongLee, J.Udugamasooriya, D.G.Udugamasooriya, D. GUdugamasooriya, D GomikaLim, Hyun SukLim, Hyun-SukLim, H.-S.Kodadek, T.Kodadek, Thomas J and Kodadek, Thomas
Nature chemical biology, vol. 6, (no. 4), pp. 258-60, 2010/Apr. | Journal Article
2009
Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator.promoter complex by the proteasomal ATPases.
Kim, Young-ChanKim, Young-ChanWu, Shwu-YuanWu, Shwu-YuanLim, Hyun SukLim, Hyun-SukChiang, Cheng-MingChiang, Cheng-MingKodadek, Thomas J and Kodadek, Thomas
The Journal of biological chemistry, vol. 284, (no. 50), pp. 34522-30, 2009/Dec/11. | Journal Article
 
Rapid identification of improved protein ligands using peptoid microarrays.
Lim, Hyun SukLim, H.-S.Reddy, M MMuralidhar Reddy, M.Xiao, XiangshuXiao, X.Wilson, JohnnieWilson, J.Wilson, RosemaryWilson, R.Connell, StevenConnell, S.Kodadek, Thomas J and Kodadek, T.
Bioorganic & medicinal chemistry letters, vol. 19, (no. 14), pp. 3866-9, 2009/Jul/15. | Journal Article
2008
Rapid identification of the pharmacophore in a peptoid inhibitor of the proteasome regulatory particle.
Lim, Hyun SukLim, H.-S.Archer, Chase TArcher, C.T.Kim, Young-ChanKim, Y.-C.Hutchens, T.Hutchens, TroyKodadek, Thomas J and Kodadek, T.
Chemical communications (Cambridge, England), (no. 9), pp. 1064-6, 2008/Mar/7. | Journal Article
2007
A Cell-Permeable Synthetic Transcription Factor Mimic
Xiao, XiangshuXiao, X.Yu, P.Yu, PengLim, Hyun SukLim, H.-S.Sikder, DevanjanSikder, D.Kodadek, Thomas J and Kodadek, T.
Angewandte Chemie (International Edition), vol. 46, (no. 16), pp. 2865-2868, 2007. | Journal Article
 
Design and synthesis of a cell-permeable synthetic transcription factor mimic.
Xiao, XiangshuYu, PengLim, Hyun SukSikder, Devanjan and Kodadek, Thomas
Journal of combinatorial chemistry, vol. 9, (no. 4), pp. 592-600, 2007 Jul-Aug. | Journal Article
 
Identification of a peptoid inhibitor of the proteasome 19S regulatory particle.
Lim, Hyun SukArcher, Chase T and Kodadek, Thomas J
Journal of the American Chemical Society, vol. 129, (no. 25), pp. 7750-1, 2007/Jun/27. | Journal Article
 
Periodate-Triggered Cross-Linking Reveals Sug2/Rpt4 as the Molecular Target of a Peptoid Inhibitor of the 19S Proteasome Regulatory Particle
Lim, Hyun SukLim, Hyun-SukCai, DiCai, DiArcher, Chase TArcher, Chase TKodadek, Thomas J and Kodadek, Thomas
Journal of the American Chemical Society, vol. 129, (no. 43), pp. 12936-12937, 2007. | Journal Article