28 Publications (Page 1 of 2)
2024
Osteoporosis treatments for intervertebral disc degeneration and back pain: a perspective
2022
Suppression of sost/sclerostin and dikkopf‐1 augment intervertebral disc structure in mice
Journal of Bone and Mineral Research. | Journal Article
2021
Raloxifene reduces sex- and age-related intervertebral disc degeneration in mice by estrogen signalingBhadouria, Neharika⋅Bhadouria, Neharika⋅Bhadouria, Neharika⋅Niziolek, Paul⋅Niziolek, Paul⋅Niziolek, Paul⋅Jordi, Omar El⋅Jordi, Omar El⋅Jordi, Omar El⋅Berman, Alicia G⋅Berman, Alicia G⋅Berman, Alicia G⋅McKinzie, David⋅McKinzie, David⋅Mc Kinzie, David⋅Wallace, Joseph M⋅Wallace, Joseph M⋅Wallace, Joseph M⋅Holguin, Nilsson⋅Holguin, Nilsson and Holguin, NilssonCold Spring Harbor Laboratory
Suppression of sost/sclerostin and dickkopf-1 promote intervertebral disc structure in miceKroon, Tori M⋅Niziolek, Paul⋅Edwards, Daniel⋅Clinkenbeard, Erica L⋅Robling, Alexander G and Holguin, NilssonCold Spring Harbor Laboratory
2020
Aging aggravates intervertebral disc degeneration by regulating transcription factors toward chondrogenesisSilva, Matthew J and Holguin, NilssonThe FASEB Journal, vol. 34, (no. 2), pp. 1982, February 2020.
| Journal Article
2019
LRP5-deficiency in OsxCreERT2 mice models intervertebral disc degeneration by aging and compressionSilva, Matthew and Holguin, NilssonCold Spring Harbor Laboratory
2018
Evaluation of loading parameters for murine axial tibial loading: Stimulating cortical bone formation while reducing loading durationSun, David⋅Brodt, Michael D⋅Zannit, Heather M⋅Holguin, Nilsson and Silva, Matthew JJournal of Orthopaedic Research, vol. 36, (no. 2), pp. 691, February 2018.
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In-Vivo Nucleus Pulposus-Specific Regulation of Adult Murine Intervertebral Disc Degeneration via Wnt/Beta-Catenin SignalingHolguin, Nilsson⋅Holguin, Nilsson⋅Silva, Matthew J and Silva, Matthew JScientific reports, vol. 8, (no. 1), pp. 14, 2018-Jul-25.
| Journal Article
2017
Early changes in the knee of healer and non‐healer mice following non‐invasive mechanical injuryDuan, Xin⋅Duan, Xin⋅Rai, Muhammad Farooq⋅Rai, Muhammad Farooq⋅Holguin, Nilsson⋅Holguin, Nilsson⋅Silva, Matthew J⋅Silva, Matthew J⋅Patra, Debabrata⋅Patra, Debabrata⋅Liao, Weiming⋅Liao, Weiming⋅Sandell, Linda J and Sandell, Linda JJournal of Orthopaedic Research, vol. 35, (no. 3), pp. 536, March 2017.
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Post-Traumatic Osteoarthritis in Mice Following Mechanical Injury to the Synovial JointRai, Muhammad Farooq⋅Rai, Muhammad⋅Duan, Xin⋅Duan, Xin⋅Quirk, James D⋅Quirk, James⋅Holguin, Nilsson⋅Holguin, Nilsson⋅Schmidt, Eric J⋅Schmidt, Eric⋅Chinzei, Nobuaki⋅Chinzei, Nobuaki⋅Silva, Matthew⋅Silva, Matthew J⋅Sandell, Linda J and Sandell, LindaScientific reports, vol. 7, (no. 1), pp. 45223, 2017-03-27.
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Therapeutic efficacy of intra-articular hyaluronan derivative and platelet-rich plasma in mice following axial tibial loadingDuan, Xin⋅Sandell, Linda J⋅Chinzei, Nobuaki⋅Holguin, Nilsson⋅Silva, Matthew J⋅Schiavinato, Antonella and Rai, Muhammad FarooqPloS one, vol. 12, (no. 4), pp. e0175682, 2017-00-00.
| Journal Article
2016
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old MiceHolguin, Nilsson⋅Brodt, Michael D and Silva, Matthew JJournal of Bone and Mineral Research, vol. 31, (no. 12), pp. 2226, December 2016.
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CORR Insights.sup.[R]: Does Sclerostin Depletion Stimulate Fracture Healing in a Mouse Model?Holguin, NilssonClinical Orthopaedics and Related Research[R], vol. 474, (no. 5), pp. 1303, 20160501.
| Journal Article
CORR Insights.sup.[R]: The NLRP3/Caspase-1/Interleukin-1[beta] Axis Is Active in Human Lumbar Cartilaginous Endplate DegenerationHolguin, NilssonClinical Orthopaedics and Related Research[R], vol. 474, (no. 8), pp. 1827, 20160801.
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Suppression of NF-?B activity via nanoparticle-based siRNA delivery alters early cartilage responses to injuryYan, Huimin⋅Duan, Xin⋅Pan, Hua⋅Holguin, Nilsson⋅Rai, Muhammad⋅Akk, Antonina⋅Springer, Luke⋅Wickline, Samuel⋅Sandell, Linda and Pham, ChristineProceedings of the National Academy of Sciences of the United States of America, vol. 113, (no. 41), pp. E6199, 20161011.
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Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injuryYan, Huimin⋅Yan, Huimin⋅Duan, Xin⋅Duan, Xin⋅Pan, Hua⋅Pan, Hua⋅Holguin, Nilsson⋅Holguin, Nilsson⋅Rai, Muhammad Farooq⋅Rai, Muhammad⋅Akk, Antonina⋅Akk, Antonina⋅Springer, Luke E⋅Springer, Luke⋅Wickline, Samuel⋅Wickline, Samuel A⋅Sandell, Linda J⋅Sandell, Linda⋅Pham, Christine and Pham, Christine T NProceedings of the National Academy of Sciences of the United States of America, vol. 113, (no. 41), pp. E6208, 20161011.
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2015
mTORC2 Signaling Promotes Skeletal Growth and Bone Formation in MiceChen, Jianquan⋅Chen, Jianquan⋅Holguin, Nilsson⋅Holguin, Nilsson⋅Shi, Yu⋅Shi, Yu⋅Silva, Matthew J⋅Silva, Matthew J⋅Long, Fanxin and Long, FanxinJournal of Bone and Mineral Research, vol. 30, (no. 2), pp. 378, February 2015.
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2014
Aging diminishes lamellar and woven bone formation induced by tibial compression in adult C57BL/6Holguin, Nilsson⋅Holguin, Nilsson⋅Brodt, Michael D⋅Brodt, Michael⋅Sanchez, Michelle⋅Sanchez, Michelle E⋅Silva, Matthew and Silva, Matthew JBone, vol. 65, pp. 91, 2014.
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The aging mouse partially models the aging human spine: lumbar and coccygeal disc height, composition, mechanical properties, and Wnt signaling in young and old miceHolguin, Nilsson⋅Aguilar, Rhiannon⋅Harland, Robin A⋅Bomar, Bradley A and Silva, Matthew JJournal of applied physiology (Bethesda, Md. : 1985), vol. 116, (no. 12), pp. 1560, 2014-Jun-15.
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2013
Adaptation of Tibial Structure and Strength to Axial Compression Depends on Loading History in Both C57BL/6 and BALB/c MiceHolguin, Nilsson⋅Holguin, Nilsson⋅Brodt, Michael D⋅Brodt, Michael⋅Sanchez, Michelle⋅Sanchez, Michelle E⋅Kotiya, Akhilesh⋅Kotiya, Akhilesh A⋅Silva, Matthew J and Silva, MatthewCalcified Tissue International, vol. 93, (no. 3), pp. 221, 20130900.
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Low-intensity vibrations partially maintain intervertebral disc mechanics and spinal muscle area during deconditioningHolguin, Nilsson⋅Holguin, Nilsson⋅Martin, John T.⋅Martin, John T⋅Elliott, Dawn M⋅Elliott, Dawn M.⋅Judex, Stefan and Judex, StefanThe Spine Journal, vol. 13, pp. 428–436.
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2011
Brief daily exposure to low-intensity vibration mitigates the degradation of the intervertebral disc in a frequency-specific mannerHolguin, Nilsson⋅Holguin, Nilsson⋅Uzer, Gunes⋅Uzer, Gunes⋅Chiang, Fu-Pen⋅Chiang, Fu-Pen⋅Rubin, Clinton T⋅Rubin, Clinton⋅Judex, Stefan and Judex, StefanJournal of Applied Physiology, vol. 111, (no. 6), pp. 1853, 2011-12-01.
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2010
Rat Intervertebral Disc Health During Hindlimb Unloading: Brief Ambulation With or Without VibrationHolguin, Nilsson⋅Holguin, Nilsson⋅Judex, Stefan and Judex, StefanAviation, space, and environmental medicine, vol. 81, (no. 12), pp. 1084, 2010-Dec.
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ReplyHolguin, Nilsson⋅Muir, Jesse⋅Rubin, Clinton and Judex, StefanThe Spine Journal, vol. 10, pp. 364–365.
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2009
Short applications of very low-magnitude vibrations attenuate expansion of the intervertebral disc during extended bed restHolguin, Nilsson⋅Holguin, Nilsson⋅Muir, Jesse⋅Muir, Jesse⋅Rubin, Clinton⋅Rubin, Clinton T⋅Judex, Stefan and Judex, StefanThe Spine Journal, vol. 9, pp. 470–477.
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