The research interests of the Witczak laboratory are focused on understanding the molecular and cellular factors that regulate skeletal muscle metabolism during both physiological and pathological conditions, such as exercise, type 2 diabetes, muscle wasting and menopause. We are interested in determining how genetic, nutritional and environmental factors coordinately regulate skeletal muscle substrate uptake and utilization, resulting in differential manifestations of tissue function in both pre-clinical animal models and clinical patient populations.
Subject areas:
- Muscle/Bone Crosstalk
- Mechanobiology