I study mechanisms underlying central nervous system damage resulting from severe malaria; identifying biomarkers of acute brain injury to prevent long-term neurodisability and poor health-related quality of life in childhood survivors of acute infectious or physical injury to the brain.
Specialties: Prognostic biomarkers of acute brain injury associated with long-term neurodisability in pediatric severe malaria; health-related quality of life after severe disease; SARS-CoV-2 prevalence & immunity
I am interested in establishing reliable, non-invasive prognostic biomarkers of acute brain injury in order to prevent long-term neurodisability in children in low- and middle-income countries because of what I see as a critical gap in research priorities in these settings.
I have supervised clinical research labs focused on immuno-epidemiology, pathogenesis and long-term outcomes in pediatric severe malaria in the United States, Kenya, and Uganda, and managed clinical trials of hydroxyurea therapy and zinc for infection prevention in sickle cell anemia in Uganda.
Her research also focuses on SARS-CoV-2 immunity and prevalence of asymptomatic infection in Indiana among children and adults.