One major area of interest is the role of neuregulin-ErbB signaling in neuronal and glial function.
One of the current lab interests is to define the precise molecular role that ErbB4 plays within migrating neuronal precursors.
A second focus of the lab has been the development of transgenic mouse tools useful for studying the nervous system.
We are currently evaluating multiple candidates that have emerged from this screen. Although our focus has been on its role in the nervous system, it is important to note that ErbB4 is essential for cardiac development and mammary epithelial cell differentiation.
Areas of Study:
- Neuregulen-ErbB signaling in the nervous system
- BAC-based transgenic mouse models of neural function
Research interests: Developmental neurobiology; receptor protein-tyrosine kinase signaling; neuregulin-ErbB signaling in the nervous system
- developmental neurobiology; the use of transgenic mouse models to study nervous system function
- Psychological and Brain Sciences