The principal focus of our research is to use organic synthesis to study problems of biological and medicinal interest. Several of the templates for our work are found in the vast array of unique substances provided by Nature. Natural products offer the opportunity to advance the art of organic synthesis and enhance our knowledge of chemical reactivity while, at the same time, positioning one to have a significant impact on emerging fields of biology and medicine. We have active and ongoing research efforts in each of the areas described below:
- Synthesis, Design, and Study of Peptide Antibiotics that Inhibit Bacterial Cell Wall Biosynthesis
- Peptidoglycan Synthesis and Bacterial Cell Morphology
- Development of HBV Capsid-binding Probes and Assembly-directed Antivirals
Subject areas:
- Bio-Organic Chemistry
- Organic
- Life
- Synthesis